Exercise Metabolism
ABAZAR Teimoori; Alireza Ruzbahani; ZAhra Karimi mehr
Abstract
Aim:. The purpose of this study was to investigate The effect of eight weeks of increasing resistance training and BCAA nanoliposome supplementation on MiR-200a, HSP60, soleus muscle mitochondrial gene expression and serum IGF-1 in aged male rats.Methods: 32 old male were randomly divided into 4 groups: ...
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Aim:. The purpose of this study was to investigate The effect of eight weeks of increasing resistance training and BCAA nanoliposome supplementation on MiR-200a, HSP60, soleus muscle mitochondrial gene expression and serum IGF-1 in aged male rats.Methods: 32 old male were randomly divided into 4 groups: control, supplement (BCAA), combined (resistant training + BCAA) and exercise. Resistance training consisted of eight weeks of ladder training with moderate intensity (70% of MVCC) and five days a week. Rats in the supplement and combined groups received BCAA nanoliposome supplement at the rate of 600 mg per kilogram of body weight by gavage 5 days a week for 8 weeks. MiR200a and HSP60 were obtained using real-time PCR method and serum IGF-1 was obtained using ELISA method. Statistical analysis was performed with two-way, one-way analysis of variance and Tukey's post hoc test.Finding: significant decrease in MiR-200a and a increase in the expression of the HSP60 gene and serum IGF-1 of rats in the combination and exercise group compared to the supplement and control groups (p=0.001)., No significant difference was observed between the control and supplement groups (p=0.105).Conclusion: The direct effect of miR-200a and HSP60 on IGF-1 signal has an important effect on muscle growth and atrophy. The increase of IGF-1 as a result of strength training and BCAA supplementation causes hypertrophy and creates an anabolic environment and can affect age-related muscle growth factors and can bring benefits in this regard for the elderly.Keywords: Resistance training, BCAA, micro RNA, HSP60.
Exercise Metabolism
Masoud Rahnama; Hamid Mohebi; Hamid Rajabi
Abstract
Purpose: The aim of this study was to compare the metabolic profile of elite male karate athletes based on their physical fitness level during different phases of six competitions in one day, similar to real karate competitions.Study method: Ten young elite karateka participated in this research. Based ...
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Purpose: The aim of this study was to compare the metabolic profile of elite male karate athletes based on their physical fitness level during different phases of six competitions in one day, similar to real karate competitions.Study method: Ten young elite karateka participated in this research. Based on the Z scores obtained from physical fitness tests, including aerobic power (Bruce test), anaerobic power (30 s Wingate test), vertical jump, 30 m sprint, and agility (9×4 m), they were divided into two groups of high (n=5) and low (n=5) physical fitness. Each karateka performed six simulated committee competitions with the same rest interval as official tournaments and according to the rules of the World Federation. Venous blood samples were collected before and after the first and sixth competition. Repeated measures ANOVA was used to investigate differences at p<0.05.Results: Decreases in pH (p<0.001), increases in tryptophan (p=0.034), lactate (p<0.001), and malondialdehyde (p=0.007), and changes in glucose (p=0.003) were significant in total measured time points. Moreover, by examining time×group interaction, a significant difference was observed between the groups in plasma lactate (p=0.014), so that it was significantly higher after the sixth competition in the low physical fitness group than the other group (5 ± 0.1 vs. 3.9 ± 0.2 mmol/L, p=0.002).Conclusion: Karate athletes with low physical fitness seem to provide a larger portion of ATP needed during the sixth competition than the first competition from the anaerobic glycolysis pathway and by consuming extracellular carbohydrate sources such as plasma glucose.
Exercise Metabolism
nasrin ramezani; mahshid dezhan; Seyed Amirhossein Mortazavi; Mozhgan Baghaee Borzabadi; zahra ahadi; Saeideh Sadat Khalili
Abstract
Diabetes is the most common endocrine disease in the world, and various methods such as exercise and physical activity are used to treat it. the aim of this study was to determine the effect of high-intensity interval training on serum glucose, insulin ,irisin and its gene expression in subcutaneous ...
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Diabetes is the most common endocrine disease in the world, and various methods such as exercise and physical activity are used to treat it. the aim of this study was to determine the effect of high-intensity interval training on serum glucose, insulin ,irisin and its gene expression in subcutaneous adipose tissue in type 2 diabetic rats. For this study, 20 males of the wistar male rat (8-10 weeks with a weight of 250-270 g) were selected and randomly divided into two groups of diabetic control and diabetic exercise. After the introductory course, the experimental group performed high-intensity exercise for 4 weeks, 5 days a week for 10 minutes as 1-minute interval at a speed of 30-40 meters per second. 48 hours after the last training session and after 12 hours of fasting, glucose and insulin values serum values and expression of irisin gene were measured in subcutaneous adipose tissue. Data were analyzed using independent t-test. The results showed that 4 weeks of high-intensity interval training reduced serum glucose levels and insulin resistance index (p = 0.001), significantly increased serum values (p = 0.001) and expressed irisin gene (P = 0.004) in subcutaneous adipose tissue was controlled in the exercise group compared to the group.High-intensity interval training can reduce serum glucose levels and insulin resistance index in type 2 diabetic rats and increase serum levels and irisin gene expression in adipose tissue. it is suggested to use this type of exercises to reduce the problems caused by type 2 diabetes.
