Exercise Metabolism
ABAZAR Teimoori; Alireza Ruzbahani; ZAhra Karimi mehr; abuzar jorbonian
Abstract
Aim:. The purpose of this study was to investigate The effect of eight weeks of increasing resistance training and BCAA nanoliposome supplementation on MiR-200a, HSP60, soleus muscle mitochondrial gene expression and serum IGF-1 in aged male rats.
Methods: 32 old male were randomly divided into 4 groups: ...
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Aim:. The purpose of this study was to investigate The effect of eight weeks of increasing resistance training and BCAA nanoliposome supplementation on MiR-200a, HSP60, soleus muscle mitochondrial gene expression and serum IGF-1 in aged male rats.
Methods: 32 old male were randomly divided into 4 groups: control, supplement (BCAA), combined (resistant training + BCAA) and exercise. Resistance training consisted of eight weeks of ladder training with moderate intensity (70% of MVCC) and five days a week. Rats in the supplement and combined groups received BCAA nanoliposome supplement at the rate of 600 mg per kilogram of body weight by gavage 5 days a week for 8 weeks. MiR200a and HSP60 were obtained using real-time PCR method and serum IGF-1 was obtained using ELISA method. Statistical analysis was performed with two-way, one-way analysis of variance and Tukey's post hoc test.
Finding: significant decrease in MiR-200a and a increase in the expression of the HSP60 gene and serum IGF-1 of rats in the combination and exercise group compared to the supplement and control groups (p=0.001)., No significant difference was observed between the control and supplement groups (p=0.105).
Conclusion: The direct effect of miR-200a and HSP60 on IGF-1 signal has an important effect on muscle growth and atrophy. The increase of IGF-1 as a result of strength training and BCAA supplementation causes hypertrophy and creates an anabolic environment and can affect age-related muscle growth factors and can bring benefits in this regard for the elderly.
Keywords: Resistance training, BCAA, micro RNA, HSP60.
Elham Motamedi; Maryam Ebrahimi; Abuzar Jorbonian
Abstract
Background: This study aimed to investigate the effect of caffeine and carbohydrate co-ingestion on anaerobic performance and muscular strength of female wushu athletes. Methods: 7 female wushu athletes with 22.00 ± 6.11 years of age, 52.96 ± 4.87 kg weight and 161.29 ± 5.28 cm height ...
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Background: This study aimed to investigate the effect of caffeine and carbohydrate co-ingestion on anaerobic performance and muscular strength of female wushu athletes. Methods: 7 female wushu athletes with 22.00 ± 6.11 years of age, 52.96 ± 4.87 kg weight and 161.29 ± 5.28 cm height participated in 1RM leg and bench press and RAST tests on 4 occasions separated by 1-week washout after accidental consumption of caffeine (6 mg/kg in 250 mL water), 8% carbohydrate (21 g in 250 mL water), caffeine+carbohydrate and placebo. Data were analyzed by repeated measure ANOVA and Bonferroni tests in SPSS26, α = 0.05).Results: caffeine alone did not affect variables (P ≥ 0.05). Carbohydrate consumption increased 1RM bench press ⁓7% (P = 0.010) and 1RM leg press ⁓16% (P = 0.033). co-ingestion of carbohydrate and caffeine improved mean power ⁓15% (P = 0.027), 1RM bench press ⁓26% (P = 0.005) and leg press ⁓39% (P = 0.027). Conclusion: it seems, that carbohydrate has more effect on strength than caffeine, but combined with caffeine it may improve mean power besides the muscular strength in female wushu athletes due to effects on the central nervous system and increasing carbohydrate effect.
