Exercise Metabolism
nasrin ramezani; mahshid dezhan; Seyed Amirhossein Mortazavi; Mozhgan Baghaee Borzabadi; zahra ahadi; Saeideh Sadat Khalili
Abstract
Diabetes is the most common endocrine disease in the world, and various methods such as exercise and physical activity are used to treat it. the aim of this study was to determine the effect of high-intensity interval training on serum glucose, insulin ,irisin and its gene expression in subcutaneous ...
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Diabetes is the most common endocrine disease in the world, and various methods such as exercise and physical activity are used to treat it. the aim of this study was to determine the effect of high-intensity interval training on serum glucose, insulin ,irisin and its gene expression in subcutaneous adipose tissue in type 2 diabetic rats. For this study, 20 males of the wistar male rat (8-10 weeks with a weight of 250-270 g) were selected and randomly divided into two groups of diabetic control and diabetic exercise. After the introductory course, the experimental group performed high-intensity exercise for 4 weeks, 5 days a week for 10 minutes as 1-minute interval at a speed of 30-40 meters per second. 48 hours after the last training session and after 12 hours of fasting, glucose and insulin values serum values and expression of irisin gene were measured in subcutaneous adipose tissue. Data were analyzed using independent t-test. The results showed that 4 weeks of high-intensity interval training reduced serum glucose levels and insulin resistance index (p = 0.001), significantly increased serum values (p = 0.001) and expressed irisin gene (P = 0.004) in subcutaneous adipose tissue was controlled in the exercise group compared to the group.High-intensity interval training can reduce serum glucose levels and insulin resistance index in type 2 diabetic rats and increase serum levels and irisin gene expression in adipose tissue. it is suggested to use this type of exercises to reduce the problems caused by type 2 diabetes.
Exercise Physiology
Ameneh Pourrahim Ghouroghchi; Nayyer Ghayyem Alaee; Sajjad Anoushiravani
Abstract
Aim: Exercise reduces weight and prevents obesity. The aim was to evaluate the effect of eight weeks of aerobic-yoga training on serum irisin, lipid profile and body composition of obese women.Method: Subjects were 16 obese female volunteers (age: 33.82±3.91 years, weight: 78.2±2.72 kg, ...
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Aim: Exercise reduces weight and prevents obesity. The aim was to evaluate the effect of eight weeks of aerobic-yoga training on serum irisin, lipid profile and body composition of obese women.Method: Subjects were 16 obese female volunteers (age: 33.82±3.91 years, weight: 78.2±2.72 kg, BMI: 30.22±1.03 kg/m2) who were randomly divided into two groups of exercise (n = 8) and control (n = 8). The experimental group performed eight weeks of aerobic-yoga training, three sessions per week, 60 minutes per session, and with an intensity of 65-75% of the reserve heart rate. Blood samples were taken 24 hours before and 48 hours after exercise, and serum Irisin, lipid profile and body composition were measured. Independent t-test and ANCOVA were used to evaluate the mean difference before and after eight weeks of aerobic-yoga training. Significance level was considered P <0.05.Results: Serum irisin levels (P<0.0001) and HDL (P=0.003) significantly increased after eight weeks of aerobic-yoga training. Meanwhile, weight (P<0.001), WHR (P<0.001), BMI (P<0.0001), fat percentage (P<0.0001), fat mass (P<0.0001), LDL (P<0.001), VLDL (P<0.0001), TG (P=0.027) and cholesterol (P=0.002) significantly reduced after 8 weeks of aerobic-yoga training compared. LBM (P = 0.579) had no significant difference after eight weeks of aerobic-yoga training.Conclusion: Aerobic-yoga exercise reduces weight and improves irisin, body composition and blood lipid profile in obese women.
Maryam Mostafavian; Ahmad Abdi; Javad Mehrabani; Alireza Barari
Abstract
Aim: Converting white adipose tissue (WAT) to brown adipose tissue (BAT) is therapeutic potential to combat obesity. The purpose of this study was to investigate the effects of aerobic training and capsaicin (Cap) on FNDC5 gene expression and irisin protein level of visceral adipose tissue in rat fed ...
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Aim: Converting white adipose tissue (WAT) to brown adipose tissue (BAT) is therapeutic potential to combat obesity. The purpose of this study was to investigate the effects of aerobic training and capsaicin (Cap) on FNDC5 gene expression and irisin protein level of visceral adipose tissue in rat fed a high-fat diet (HFD).Methods: 40 male Wistar rats were fed a normal diet (ND, n = 8) or HFD (n = 32) for 8 weeks. After 8 weeks, all rats were divided into 5 groups: ND, HFD, high-fat diet-training (HFDT), high-fat diet-capsaicin (HFDCap), high-fat diet-training-capsaicin (HFDTCap). Training groups have performed a progressive aerobic running program (at 15-25 m/min, 30-60 min/day, and 5 days/week) on a motor-driven treadmill for eight weeks. Capsaicin (4 mg/kg/day) were administered orally, by gavage, once a day. Results: The results of this study showed that FNDC5 expression (p=0.001) and irisin (p=0.000) was decreased in HFD group compared to ND group. Also, the expression of FNDC5 and irisin in HFDT (Respectively p=0.006, p=0.020), HFDCap (Respectively p=0.005, p=0.021) and HFDTCap (Respectively p=0.000, p=0.000) groups was significantly increased compared to HFD. The expression of FNDC5 and irisin in HFDTCap was also significantly increased compared to HFDT (Respectively p=0.037, p=0.035) and HFDCap (Respectively p=0.044, p=0.033) groups.Conclusions: Aerobic training combination with capsaicin with increased FNDC5 and irisin in visceral adipose tissue, had Interactive effects on factors affecting browning of adipose tissue.
Z Rostami Hashjin; R Amirsasan; S Nikoukheslat; V Sari-Sarraf
Abstract
Aim: Irisin is one of the factors that mediate beneficial effects of exercise on adipose tissue conversion, uncoupling protein1 (UCP1) and metabolism. Therefore, the aim of this study was to determine the effect of six weeks high intensity interval training (HIIT) with Turmeric supplementation on Irisin, ...
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Aim: Irisin is one of the factors that mediate beneficial effects of exercise on adipose tissue conversion, uncoupling protein1 (UCP1) and metabolism. Therefore, the aim of this study was to determine the effect of six weeks high intensity interval training (HIIT) with Turmeric supplementation on Irisin, UCP1 and body composition in obese females. Method: Thirty obese women (BMI=33.08±1.78 kg.m-2) age range of 20-25 years in quasi-experimental study with pre-post testing design, were selected purposefully and were randomly divided into two homogeneous groups of 15 participants: HIIT+placebo, and HIIT+Turmeric supplementation (3 milligram curcumin per kilogram body weight per day). Preparation period performed for 3 weeks and HIIT performed for six weeks (4 sessions per week). Blood samples were taken, before and 24 hours after last exercise session in the follicular phase. Serum irisin and UCP1 were measured by ELISA method. Results: In both groups, irisin levels, subcutaneous fat and BMI significantly decreased (P<0.05), and UCP1 levels and VO2max significantly increased after nine weeks intervention (P<0.05). There was no significant difference between groups for irisin, UCP1, total subcutaneous fat, BMI and VO2max values. Conclusion: Six weeks high intensity interval training with turmeric supplementation probably could improve body composition by decreasing Irisin and increasing UCP1 levels.
Parvin Khodadadi; Hamid Mohebbi
Volume 5, Issue 2 , February 2016, , Pages 99-108
Abstract
Aim: Irisin mediate the beneficial effects of exercise on energy metabolism. However, irisin response to resistance exercise and its related training variables has been less discussing. The purpose of this study was to determine the effect of resistance exercise order on serum irisin and blood lactate ...
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Aim: Irisin mediate the beneficial effects of exercise on energy metabolism. However, irisin response to resistance exercise and its related training variables has been less discussing. The purpose of this study was to determine the effect of resistance exercise order on serum irisin and blood lactate concentration in overweight women. Method: Eight overweight women (age, 41.6±4.5 years; height, 161±0.1 cm; weight, 73.8±4.5 kg; BMI, 28.6±1 kg/m2) performed 2 exercise sessions separated by one week using a randomized cross-over design. The two sessions were composed of the same exercises performed in the opposite exercise order including: exercise order from large to small muscles (leg press, chest press, rows, leg extension, overhead press, leg curl, biceps curl, triceps extension) or small to large muscles (reverse sequence from large to small muscles). All exercises were performed with %80 1RM in 3 sets with 10 repetitions and 2 minutes of rest between the sets and exercises. Blood samples were collected before and immediately after exercise at each session. Data were analyzed using paired t-test and Pearson̕ s correlation coefficient. Results: A significant increase was observed in the serum irisin and blood lactate immediately after both resistance exercise orders (P≤0.05). Blood lactate concentration after exercise order from large to small muscles significantly higher than exercise order from small to large muscles (P≤0.05), while, serum irisin changes were no significant between exercise orders. As well as, there was positive and significant correlation between lactate and irisin in both resistance exercise orders (P≤0.05). Conclusion: Resistance exercise can lead to increase serum irisin in overweight women, that this enhancement is independent of exercise order.
