Investigation of the Effect of Interval Training on the Expression of Humanin and MOTS-c Genes in Obese Diabetic Mice
Investigation of the Effect of Interval Training on the Expression of Humanin and MOTS-c Genes in Obese Diabetic Mice

Marziye Khatibzadeh; Sadegh Cheragh Birjandi; Najmeh Rezaeian; Vahid Rezaei

Volume 15, Issue 2 , October 2025, , Pages 92-107

https://doi.org/10.22124/jme.2025.31668.427

Abstract
  Introduction: Obesity and overweight are major global public health concerns. Obesity-related diabetes leads to mitochondrial dysfunction in adipocytes and promotes inflammation. The ...  Read More
Effect of two types of intense training on the levels of thioredoxin reductase-1 enzyme and malondialdehyde in testicular tissue of male wistar rats
Effect of two types of intense training on the levels of thioredoxin reductase-1 enzyme and malondialdehyde in testicular tissue of male wistar rats

mehran hashemi; Agha Ali Ghasemnyian; akram karimi asl; samaneh hadi

Volume 13, Issue 1 , April 2023, , Pages 101-115

https://doi.org/10.22124/jme.2023.24158.286

Abstract
  Background and Aim:The aim of the present study was to investigate the effect of two types of intense training on the levels of thioredoxin reductase-1 enzyme and malondialdehyde in ...  Read More
Investigation of Excessive Autophagy in Visceral Adipose Tissue of Type 2 Diabetic Rats Following Eight Weeks of High-Intensity Interval Training and Moderate-Intensity Continuous Training
Investigation of Excessive Autophagy in Visceral Adipose Tissue of Type 2 Diabetic Rats Following Eight Weeks of High-Intensity Interval Training and Moderate-Intensity Continuous Training

Hadi Golpasandi; Mohammad Rahman Rahimi; Peyman Ghasemi; Slahadin Ahmadi; Siamand Abdollahpour

Volume 15, Issue 1 , August 2025, , Pages 103-120

https://doi.org/10.22124/jme.2025.30622.408

Abstract
  Introduction: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance and hyperglycemia, often accompanied by dysregulation of lipid metabolism ...  Read More
Effects of L-Arginine supplementation on fat and carbohydrate metabolism during high intensity interval exercise in overweight individuals
Effects of L-Arginine supplementation on fat and carbohydrate metabolism during high intensity interval exercise in overweight individuals

Minoo Bassami; Banipal Tataroo; Sajad Ahmadizad

Volume 9, Issue 2 , November 2020, , Pages 105-116

https://doi.org/10.22124/jme.2020.14066.165

Abstract
  Purpose: The present study was designed to investigate the effects of L-Arginine supplementation on fat and carbohydrate metabolism during high intensity interval exercise (HIIE) in ...  Read More
The effect of aerobic training with resveratrol on the inflammatory and antioxidant indices of the hippocampus of rats with Alzheimer's disease
The effect of aerobic training with resveratrol on the inflammatory and antioxidant indices of the hippocampus of rats with Alzheimer's disease

Ammar Rashet; Ahmad Abdi; alireza barari

Volume 14, Issue 2 , December 2024, , Pages 105-125

https://doi.org/10.22124/jme.2024.26320.342

Abstract
  Introduction: To date, there is no cure or effective treatment for Alzheimer’s disease (AD). Promoting regular exercise and a diet containing polyphenols are effective non-pharmacological ...  Read More
Response of Liver Tissue Oxidative Indices to Bisphenol-A intoxicated Rats to Eight Weeks of Aerobic Training with and without Zinc Supplementation (Zinc Nanoparticles and Nanoparticles)
Response of Liver Tissue Oxidative Indices to Bisphenol-A intoxicated Rats to Eight Weeks of Aerobic Training with and without Zinc Supplementation (Zinc Nanoparticles and Nanoparticles)

Mohammad Salmasi; Asghar Tofighi; Siamak Asri; Javad Tolouei Azar

Volume 12, Issue 2 , March 2022, , Pages 106-129

https://doi.org/10.22124/jme.2023.24007.270

Abstract
  Aims: The purpose of this study was to investigate the effect of moderate-intensity aerobic exercise with and without supplementation of nanoparticles and zinc oxide salts on hepatocyte ...  Read More
The Effect of Progressive and Constant Load Resistance Training on Serum and Hepatic Levels of ANGPTL4 in Sucrose-Fed Rats
The Effect of Progressive and Constant Load Resistance Training on Serum and Hepatic Levels of ANGPTL4 in Sucrose-Fed Rats

Elham Khorrami; Alireza Safarzade; Elahe Talebi-Garakani

Volume 15, Issue 2 , October 2025, , Pages 108-123

https://doi.org/10.22124/jme.2025.30602.407

Abstract
  Background and Purpose: Hepatokines are key regulators of metabolism, and the angiopoietin-like protein 4 (ANGPTL4) plays an important role in lipid metabolism. This study aimed to ...  Read More
The Effect of Hatha Yoga Training on Nesfatine-1, Appetite and Obesity indices in Overweight Women
The Effect of Hatha Yoga Training on Nesfatine-1, Appetite and Obesity indices in Overweight Women

Soniya Fateh; Azam Zarneshan; Bahloul Ghorbanian

Volume 12, Issue 1 , March 2022, , Pages 109-126

https://doi.org/10.22124/jme.2023.23946.245

Abstract
  Aim: The effect of exercises that consist of a set of mental and physical exercise has received less attention on reducing appetite and obesity. The aim of this study was to investigate ...  Read More
Effect of  elastic-band resistance training on myostatin, follistatin levels in elderly women with osteosarcopenic obesity
Effect of elastic-band resistance training on myostatin, follistatin levels in elderly women with osteosarcopenic obesity

Negin Kazemipour; Mohammad Faramarzi; Ebrahim Banitalebi

Volume 9, Issue 2 , November 2020, , Pages 117-136

https://doi.org/10.22124/jme.2020.16235.191

Abstract
  Purpose: Myostatin, its inhibitor follistatin have been proposed as factors that could potentially modify biological aging. The purpose of this study was to investigate the effect of ...  Read More
Effect of ischemic preconditioning and beetroot supplementation on anaerobic performance of man cyclists
Effect of ischemic preconditioning and beetroot supplementation on anaerobic performance of man cyclists

nazanin khosravaniyan; zahra mosallanezhad; mehrzad moghadasi; hadi bashafaat

Volume 13, Issue 1 , April 2023, , Pages 117-131

https://doi.org/10.22124/jme.2023.23947.248

Abstract
  purpose: One of the new training methods to increase the performance of athletes is ischemic preconditioning (IPC). the aim of the present study was the effect of ischemic preconditioning ...  Read More
The effect of aerobic exercise on liver enzymes and insulin resistance in people with type 2 diabetes: A systematic review and meta-analysis
The effect of aerobic exercise on liver enzymes and insulin resistance in people with type 2 diabetes: A systematic review and meta-analysis

Khadijeh Molaei; Omid Zafarmand; Mehdi Mogharnasi

Volume 15, Issue 1 , August 2025, , Pages 121-144

https://doi.org/10.22124/jme.2025.29671.390

Abstract
  Introduction: Diabetes is associated with many pathological changes, and liver damage is one of the most important consequences of diabetes. The aim of the present study was to investigate ...  Read More
Interaction effect of Aerobic Training and Berberine Chloride intake on the Expression of TGF-β and Smad4 of Heart Tissue in Streptozotocin-Induced Diabetic Rats
Interaction effect of Aerobic Training and Berberine Chloride intake on the Expression of TGF-β and Smad4 of Heart Tissue in Streptozotocin-Induced Diabetic Rats

Ghasem Torabi Palat Kaleh; Mostafa Kazemi; Soraya Saeidi

Volume 11, Issue 1 , March 2022, , Pages 123-137

https://doi.org/10.22124/jme.2022.22257.229

Abstract
  Aim: Diabetes leads to extensive cardiac fibrosis, which worsens as disease progresses, culminating in diabetic cardiomyopathy. In this study, we investigated the effect of aerobic ...  Read More
The effect of aerobic exercise and resveratrol on hippocampal mitochondrial fusion in rats with Alzheimer's disease
The effect of aerobic exercise and resveratrol on hippocampal mitochondrial fusion in rats with Alzheimer's disease

Saqqa Farajtabar Behrestaq; Mahla Hosseini Tabatabaei

Volume 15, Issue 2 , October 2025, , Pages 124-139

https://doi.org/10.22124/jme.2025.31445.422

Abstract
  Introduction: Alzheimer's disease (AD) is the most common neurodegenerative disease affecting more than 50 million people worldwide. The aim of the present study was to determine the ...  Read More
The effect of eight weeks of high-intensity intermittent aerobic training on the levels of SERCA2 and Akt proteins Cardiomyocytes of rats with type 2 diabetes
The effect of eight weeks of high-intensity intermittent aerobic training on the levels of SERCA2 and Akt proteins Cardiomyocytes of rats with type 2 diabetes

Ali Shabani Fard; Mohsen Ghanbarzadeh; Aliakbar Alizadeh; Rouhollah Ranjbar

Volume 14, Issue 2 , December 2024, , Pages 125-144

https://doi.org/10.22124/jme.2024.27067.354

Abstract
  Introduction: The purpose of this study was to investigate the effect of eight weeks of high intensity interval training (HIIT) on the levels of SERCA2a and Akt proteins in the heart ...  Read More
The effect of two months of combined exercise training on IRE1α and PERK gene expression in the vastus lateralis muscle of male Wistar rats.
The effect of two months of combined exercise training on IRE1α and PERK gene expression in the vastus lateralis muscle of male Wistar rats.

Zahra Esmaeili; Farzad Zehsaz; Alireza Nourazar

Volume 12, Issue 1 , March 2022, , Pages 127-140

https://doi.org/10.22124/jme.2023.23967.262

Abstract
  Purpose: The present study aimed to determine 2 months of combined exercise training on the expression of PERK and IRE1α genes in Wistar male rats' Vastus lateralis muscle.Method: ...  Read More
Effect of supplementation of L-arginine on platelet indices in response to a high intensity interval exercise in overweight men
Effect of supplementation of L-arginine on platelet indices in response to a high intensity interval exercise in overweight men

Siamak Rahbar; Sajad Ahmadizad; Hiwa Rahmani

Volume 12, Issue 2 , March 2022, , Pages 130-142

https://doi.org/10.22124/jme.2023.24036.276

Abstract
  Objective: To investigate the effect of L-arginine supplementation on platelet indices in response to a high intensity interval exercise.Methods: Ten healthy overweight young men (BMI=27 ...  Read More
Interactive effect of aerobic training with Saffron extract on BAX and Bcl2 proteins of cardiac tissue in trained rats following an aerobic exercise until exhaustion
Interactive effect of aerobic training with Saffron extract on BAX and Bcl2 proteins of cardiac tissue in trained rats following an aerobic exercise until exhaustion

amir khosravi

Volume 13, Issue 1 , April 2023, , Pages 132-156

https://doi.org/10.22124/jme.2023.23954.252

Abstract
  Objective: Aerobic training and Saffron has decreasing effects on apoptosis induced by exercise to exhaustion. The present study aims to investigate the Interactive effect of aerobic ...  Read More
The effect of eight weeks moderate-intensity endurance training on hypocampic brain-derived neurotrophic factor and tyrosine kinase B receptor gene expression in the rats with hippocampal degeneration model
The effect of eight weeks moderate-intensity endurance training on hypocampic brain-derived neurotrophic factor and tyrosine kinase B receptor gene expression in the rats with hippocampal degeneration model

Fatemeh Akbari; mehrzad moghadasi; Sirus Farsi Farsi; Mohammad Amin Edalatmanesh

Volume 9, Issue 2 , November 2020, , Pages 137-147

https://doi.org/10.22124/jme.2020.15180.172

Abstract
  The purpose of the present study was to examine the effect of eight weeks moderate-intensity endurance training on hypocampic brain-derived neurotrophic factor (BDNF) and tyrosine kinase ...  Read More
The effect of 10 weeks aerobic exercise and consumption of safflower seed extract on PIK3R1 gene expression and kidney function after consumption of dexamethasone in male rats
The effect of 10 weeks aerobic exercise and consumption of safflower seed extract on PIK3R1 gene expression and kidney function after consumption of dexamethasone in male rats

Hannaneh khalili ateni; Rozita Fathi; khadijeh Nasiri; Abolfazl Akbari

Volume 11, Issue 1 , March 2022, , Pages 139-159

https://doi.org/10.22124/jme.2022.21872.227

Abstract
  Aim: The aim of present study is to evaluate the effects of ten weeks of aerobic exercise and consumption of safflower seed extract on PIK3R1gene expression and serum creatinine levels ...  Read More
The effect of six weeks of aerobic training and consumption of pineapple extract on HSP70 and CD147 gene expression in tumor tissues of mice with melanoma cancer
The effect of six weeks of aerobic training and consumption of pineapple extract on HSP70 and CD147 gene expression in tumor tissues of mice with melanoma cancer

Maryam Movassagh; Hossein Abednatanzi; mandana gholami; Farshad Ghazalian

Volume 15, Issue 2 , October 2025, , Pages 140-160

https://doi.org/10.22124/jme.2025.31148.417

Abstract
  Introduction and Objective: Targeted therapy of growth and immune factors may lead to more effective inhibition of tumor proliferation and progression in melanoma cancer. The aim of ...  Read More
Changes in Angiopoietin-like 4 Protein Level and Insulin Resistance in Rats with Non-Alcoholic Fatty Liver Disease: Effect of High Intensity Interval Training and Portulaca Oleracea extract
Changes in Angiopoietin-like 4 Protein Level and Insulin Resistance in Rats with Non-Alcoholic Fatty Liver Disease: Effect of High Intensity Interval Training and Portulaca Oleracea extract

Somayeh Kazemi-Esfahani; Ali Yaghoubi

Volume 12, Issue 1 , March 2022, , Pages 141-158

https://doi.org/10.22124/jme.2023.24110.284

Abstract
  Introduction: The aim of this study was to investigate the effect of eight weeks of high intensity interval training (HIIT) and Portulaca Oleracea extract on Angiopoietin-like 4 Protein ...  Read More
The effect of simulating staying at moderate altitude with thyme consumption on cardiomyopathy and liver enzymes in Rats  with type 2 diabetes
The effect of simulating staying at moderate altitude with thyme consumption on cardiomyopathy and liver enzymes in Rats with type 2 diabetes

mahdi faramoushi; Ramin Amirsasan; Vahid sari sarraf

Volume 12, Issue 2 , March 2022, , Pages 143-162

https://doi.org/10.22124/jme.2023.24199.288

Abstract
  the aim of study was to investigate the effect of simulating staying at medium altitude along with consumption of thyme on the cardiomyopathy rate of type 2 diabetic rats and their ...  Read More
The effect of a two-week supplementation of pomegranate seed powder on the biomarkers of oxidative stress and physical performance in female volleyball players following a volleyball tournament
The effect of a two-week supplementation of pomegranate seed powder on the biomarkers of oxidative stress and physical performance in female volleyball players following a volleyball tournament

Elaheh Piralaiy; Ramin Amirsasan; zeinab ali bakhsi fard; Siamak Rahbar

Volume 14, Issue 2 , December 2024, , Pages 145-168

https://doi.org/10.22124/jme.2024.27337.361

Abstract
  Introduction: Strenuous sports activities increase oxidative stress. This study aimed to determine the impact of a two-week supplementation of pomegranate seed powder on the biomarkers ...  Read More
The effect of resistance training and omega-3
supplementation on some factors involved in muscle
hypertrophy in young female
The effect of resistance training and omega-3 supplementation on some factors involved in muscle hypertrophy in young female

Farnaz Alibabaeiyan Qazvini; Abbas Sadeghi; Hassan Pourrazi

Volume 15, Issue 1 , August 2025, , Pages 145-158

https://doi.org/10.22124/jme.2025.25762.329

Abstract
  Research Aim: Resistance exercise training (RET) is potential stimulus to induce hypertrophy and it can be increased through processes related to myokines which can be synthesized by ...  Read More
The effect of 8 weeks resistance exercise on cardaic apoptosis biomarkers in diabetic rats
The effect of 8 weeks resistance exercise on cardaic apoptosis biomarkers in diabetic rats

hamideh montazery taleghani; nader shakeri; khosrow ebrahim; rahman soori; M Gholami

Volume 9, Issue 2 , November 2020, , Pages 149-161

https://doi.org/10.22124/jme.2020.15392.177

Abstract
  Background: A main reason of death in diabetes is cardiovascular diseases, which apoptosis plays a critical role through the progress. As known, body exercises can avoid damaging effects ...  Read More