University of Guilan Metabolism and Exercise 2322-2867 5 1 2015 05 22 Action of L-Arginin on oxidative- nitrosative stress induced by acute exercise in liver of rats Action of L-Arginin on oxidative- nitrosative stress induced by acute exercise in liver of rats 1 9 1690 FA Masume Kazemi Sayad Mohmmad Marandi Associate professor, University of Isfahan Ahmand Movahedian Attar professor, Isfahan University.of Medical Sciences Hosin Mohammadian PhD student in Pharmaceutical Biotechnology Hamid Reza Sharifi Jebeli Veterinary Technician Journal Article 2015 04 05 Aim: The aim of the present investigation is evaluate the effect of L- Arginine supplements on the oxidative and nitrosative stress in liver of rats following acute exercise on a treadmill. Method: Thirty two male Vistar rats (160-210 g) were randomly divided into four groups: control (C); L-Arg treatment (Arg); exhaustive exercise (E); and exhaustive exercise with L-Arg treatment (E + Arg). E and E+Arg groups performed a 1 hour acute running test, or until exhaustion on a treadmill (16-26 m/min) and Arg and E+Arg groups treated orally with the L-Arg (2% diet, for 30 days). Sampling was performed 1 hour after exercise. Nitric oxide production was evaluated by measuring nitrite formation, using Griess reagent. oxidant-Antioxidant’s ratio was measured as TOS/ TAC levels. Results: According to the means of the oxidant-antioxidant’s balance (E)=0.91±0.12, (SC+Arg)=0.92 0.04 and (E+Arg)=0.91±0.09, TOS/TAC decreased in (E), (SC+Arg) and (E+Arg) groups compared with control group (SC); however, this decrease was not significant. And the results showed nitric oxide in (SC) group (mean=9.01 6.31 ) was more than other groups, but there was no significant change in there. Conclusion: The results of the present study didn’t show existence of oxidative-nitrosative stress and supplementation effect in muscle 1 h after acute exercise. Aim: The aim of the present investigation is evaluate the effect of L- Arginine supplements on the oxidative and nitrosative stress in liver of rats following acute exercise on a treadmill. Method: Thirty two male Vistar rats (160-210 g) were randomly divided into four groups: control (C); L-Arg treatment (Arg); exhaustive exercise (E); and exhaustive exercise with L-Arg treatment (E + Arg). E and E+Arg groups performed a 1 hour acute running test, or until exhaustion on a treadmill (16-26 m/min) and Arg and E+Arg groups treated orally with the L-Arg (2% diet, for 30 days). Sampling was performed 1 hour after exercise. Nitric oxide production was evaluated by measuring nitrite formation, using Griess reagent. oxidant-Antioxidant’s ratio was measured as TOS/ TAC levels. Results: According to the means of the oxidant-antioxidant’s balance (E)=0.91±0.12, (SC+Arg)=0.92 0.04 and (E+Arg)=0.91±0.09, TOS/TAC decreased in (E), (SC+Arg) and (E+Arg) groups compared with control group (SC); however, this decrease was not significant. And the results showed nitric oxide in (SC) group (mean=9.01 6.31 ) was more than other groups, but there was no significant change in there. Conclusion: The results of the present study didn’t show existence of oxidative-nitrosative stress and supplementation effect in muscle 1 h after acute exercise.

https://jme.guilan.ac.ir/article_1690_752fccb5a81865a93c60f004e69579af.pdf

University of Guilan Metabolism and Exercise 2322-2867 5 1 2015 05 22 Plasma visfatin response to acute endurance exercise pre and post 8-weeks training in obese healthy men Plasma visfatin response to acute endurance exercise pre and post 8-weeks training in obese healthy men 11 21 1691 FA Nahid Bijeh Associate professor, Ferdowsi University of Mashhad Hasan Faraji Instructor, Department of Physical Education and Sport Sciences, Marivan Branch, Islamic Azad University Babisan Askari PhD student in Exercise Physiology Asra Askari Instructor, Department of Physical Education and Sport Sciences, Gorgan Branch, Islamic Azad University Saeid Ramezani Instructor, Department of Physical Education and Sport Sciences, Payame Noor University Journal Article 2015 07 29 Aim: The purpose of this study was to examine the response of the visfatin to acute endurance exercise pre and post 8-weeks trainingin untrained obese healthy men. Method: Twenty two subjects (age 29.06±3.83 years, weight 90.96±4.68 kg, height 171.3±4.88 cm, and BMI 30.76±1.8 kg/m2) were volunteered to participate in the current study. The subjects were divided randomly into two experimental (n=11) and control (n=11) groups. Experimental group participated in 8-week endurance training program three times per week. Exercise intensity increased from 60 percent of maximum heart rate to 65 to 70 percent after 4thweeks until the end of training program. Acute exercise test (cycle ergometer exercise, 30 min at 60 percent of maximum heart rate) were employed before and after training period. Blood samples were collected before, immediately, and 30 min after acute exercise at before and after endurance training period to measure plasma visfatin variations. Results: The results by two-way Anova with analysis showed before training period, visfation levels changes were not sigificant after acute exercise , immediately and 30 min aftery in both groups. Conclusion: These data indicate that endurance training is associated with decrease in resting plasma visfatin and body fat in obese men. Moreover, one bout of endurance training can decrease the plasma visfatin in response to acute exercise. Aim: The purpose of this study was to examine the response of the visfatin to acute endurance exercise pre and post 8-weeks trainingin untrained obese healthy men. Method: Twenty two subjects (age 29.06±3.83 years, weight 90.96±4.68 kg, height 171.3±4.88 cm, and BMI 30.76±1.8 kg/m2) were volunteered to participate in the current study. The subjects were divided randomly into two experimental (n=11) and control (n=11) groups. Experimental group participated in 8-week endurance training program three times per week. Exercise intensity increased from 60 percent of maximum heart rate to 65 to 70 percent after 4thweeks until the end of training program. Acute exercise test (cycle ergometer exercise, 30 min at 60 percent of maximum heart rate) were employed before and after training period. Blood samples were collected before, immediately, and 30 min after acute exercise at before and after endurance training period to measure plasma visfatin variations. Results: The results by two-way Anova with analysis showed before training period, visfation levels changes were not sigificant after acute exercise , immediately and 30 min aftery in both groups. Conclusion: These data indicate that endurance training is associated with decrease in resting plasma visfatin and body fat in obese men. Moreover, one bout of endurance training can decrease the plasma visfatin in response to acute exercise.

https://jme.guilan.ac.ir/article_1691_4c51baed6aaed97a7aeabdbd1e6e2da1.pdf

University of Guilan Metabolism and Exercise 2322-2867 5 1 2015 05 22 Effects of 12 weeks high intensity interval training on plasma Adiponectin, Leptin and insulin resistance in obese males with non-alcoholic fatty liver Effects of 12 weeks high intensity interval training on plasma Adiponectin, Leptin and insulin resistance in obese males with non-alcoholic fatty liver 23 34 1692 FA Reza Rezaee Shirazi Assistant Professor, Islamic Azad University, Aliabad Katoul Branch Journal Article 2015 09 27 Aim: The main objective of the study was to consider the impact of 12 weeks high intensity interval training on plasma Adiponectin, Leptin and insulin resistance in 20-35 years old obese males with non-alcoholic fatty liver. Method: In this study researchers used of thirty eight participants with means of age 28.5±6.2 yrs, weight 95.4±11.8 kg and height 178.6±14.7 cm were randomly divided into two groups including experimental (N=18) and control (N=20) groups. The experimental group performed high intensity interval training for 36 sessions and 3 days per week. Intensity of training in the first session was determined with 90% of peak power output in subjects and 115% of peak power output in last session. The protocol training was 10 sets of 60 seconds repetitions of pedaling a bicycle ergometer with 60 seconds rest to 15% peak power output during exercise. Once normal distribution of collected data has been analyzed by K-S test, the pre and post mean difference significant has been analyzed by using t-paired test (p≤0.05). Results: After 12 weeks high intensity interval training in obese males with fatty liver, the results have shown a significant decrease in Leptin level, and a significant decrease in Insulin resistance level (p<0.05). However, the Adiponectin level had shown a significant increase between pre-test and post-test (p≤0.05). Conclusion: : Finally, the results have shown that12 weeks high intensity interval training in obese males with fatty liver could change Adiponectin, Leptin and Insulin resistance levels. Also, any decrease in body mass index and weight, resulted in disorder improvement. Aim: The main objective of the study was to consider the impact of 12 weeks high intensity interval training on plasma Adiponectin, Leptin and insulin resistance in 20-35 years old obese males with non-alcoholic fatty liver. Method: In this study researchers used of thirty eight participants with means of age 28.5±6.2 yrs, weight 95.4±11.8 kg and height 178.6±14.7 cm were randomly divided into two groups including experimental (N=18) and control (N=20) groups. The experimental group performed high intensity interval training for 36 sessions and 3 days per week. Intensity of training in the first session was determined with 90% of peak power output in subjects and 115% of peak power output in last session. The protocol training was 10 sets of 60 seconds repetitions of pedaling a bicycle ergometer with 60 seconds rest to 15% peak power output during exercise. Once normal distribution of collected data has been analyzed by K-S test, the pre and post mean difference significant has been analyzed by using t-paired test (p≤0.05). Results: After 12 weeks high intensity interval training in obese males with fatty liver, the results have shown a significant decrease in Leptin level, and a significant decrease in Insulin resistance level (p<0.05). However, the Adiponectin level had shown a significant increase between pre-test and post-test (p≤0.05). Conclusion: : Finally, the results have shown that12 weeks high intensity interval training in obese males with fatty liver could change Adiponectin, Leptin and Insulin resistance levels. Also, any decrease in body mass index and weight, resulted in disorder improvement.

https://jme.guilan.ac.ir/article_1692_c406d9a4406ba68a8d30ddaed2fb5280.pdf

University of Guilan Metabolism and Exercise 2322-2867 5 1 2015 05 22 Effect of zizyphus jujube extract and resistance exercise on liver damaging biomarkers in male toxicated by anabolic steroid Effect of zizyphus jujube extract and resistance exercise on liver damaging biomarkers in male toxicated by anabolic steroid 35 44 1693 FA Kazem Ranjbar PhD Student in Exercise Physiology Hasan Matinhomaee Assistace professor, Islamic Azad University Central Tehran Branch Mohammad Ali Azarbayjani professor, Islamic Azad University Central Tehran Branch Maghsood Peeri Associate professor, Islamic Azad University Central Tehran Branch Journal Article 2015 11 25 Aim: Effect of zizyphus jujube extract and resistance exercise on liver damaging biomarkers in male rats toxicated by anabolic steroid. Method: 42 Wistar rats were randomly divided into six equal groups: group 1: control, group 2: sham, group 3: anabolic steroid (5 mg/kg), group 4: anabolic steroid (5 mg/kg) + zizyphus jujube extract (600 mg/kg), group 5: anabolic steroid (5 mg/kg) + resistance exercise, and group 6: anabolic steroid (5 mg/kg) + zizyphus jujube extract (600 mg/kg) + resistance exercise. Apart from the control and sham groups, anabolic steroid with a 5 mg per kg dose was injected to other groups once a week. The resistance exercise protocol were consisted of three exercise sessions per week by 5 repetitions in 3 sets of climbing ladder for eight weeks. The data were analyzed by the SPSS software, using ANOVA. Results: The results of this study revealed a significant increase in liver enzymes (ALT, AST, and ALP) and direct and total bilirubins in the anabolic steroid group (group 3) compared to the control and sham groups (p < 0.05). In addition, zizyphus jujube treatment (group 4), resistance exercise (group 5), and treatment with resistance exercise (group 6) caused a significant decrease in liver enzymes (ALT, AST, and ALP) and direct and total Bilirubins. There were no-significant differences in albumin concentration between experimental groups Conclusion: : Zizyphus jujube extract consumption as well as resistance exercise caused a significant decrease in liver damaging biomarkers. Hence, the simultaneous use of resistance exercise and zizyphus jujube extract did not show any increasing effect on these biomarkers. Aim: Effect of zizyphus jujube extract and resistance exercise on liver damaging biomarkers in male rats toxicated by anabolic steroid. Method: 42 Wistar rats were randomly divided into six equal groups: group 1: control, group 2: sham, group 3: anabolic steroid (5 mg/kg), group 4: anabolic steroid (5 mg/kg) + zizyphus jujube extract (600 mg/kg), group 5: anabolic steroid (5 mg/kg) + resistance exercise, and group 6: anabolic steroid (5 mg/kg) + zizyphus jujube extract (600 mg/kg) + resistance exercise. Apart from the control and sham groups, anabolic steroid with a 5 mg per kg dose was injected to other groups once a week. The resistance exercise protocol were consisted of three exercise sessions per week by 5 repetitions in 3 sets of climbing ladder for eight weeks. The data were analyzed by the SPSS software, using ANOVA. Results: The results of this study revealed a significant increase in liver enzymes (ALT, AST, and ALP) and direct and total bilirubins in the anabolic steroid group (group 3) compared to the control and sham groups (p < 0.05). In addition, zizyphus jujube treatment (group 4), resistance exercise (group 5), and treatment with resistance exercise (group 6) caused a significant decrease in liver enzymes (ALT, AST, and ALP) and direct and total Bilirubins. There were no-significant differences in albumin concentration between experimental groups Conclusion: : Zizyphus jujube extract consumption as well as resistance exercise caused a significant decrease in liver damaging biomarkers. Hence, the simultaneous use of resistance exercise and zizyphus jujube extract did not show any increasing effect on these biomarkers.

https://jme.guilan.ac.ir/article_1693_8a0752b1551e8a51141815d4984e85fa.pdf

University of Guilan Metabolism and Exercise 2322-2867 5 1 2015 05 22 The effect of 12 weeks high intensity interval training (HIIT) on testosterone, cortisol and lipid profile levels in obese and overweight boys The effect of 12 weeks high intensity interval training (HIIT) on testosterone, cortisol and lipid profile levels in obese and overweight boys 45 58 1694 FA Alireza Paahoo Msc in Exercise Physiology Vahid Tadibi Associate professor, Razi University Naser Behpoor Journal Article 2015 08 17 Aim: Obesity and overweight along with metabolic disorders associated with them is one of the very important concerns in today’s world. According to the fact that chihdren and adolencrs bodies are in asensetive stage of growth and preparation for aduhthood, we aim to review the effects of high intensity interval training over the course of 12 weeks on testosterone, cortisol and lipids profiles levels in obese and overweight. Method: In this study 20 boys were selected based on per- post test in to control and high intensity interval training (HIIT) groups.Anthropometric measures, maximal aerobic speed (MAS), cortisol and testosterone levels, and lipid profile were measured in all subjects before and after training. Training group participated in a training program at 100 to 110% of MAS and 3 times per week during 12 weeks. Independent t-test and Paired t-test with a significance level of (P≤0/05) was used to analysis variables. Results: Following the training program, in training group, anthropometric measures including weight, BMI, percentage body fat and waist-hips ratio and cortisol resting level, TC, TG, LDL-C decreased, and HDL-C increased but no effect on testostron resting levels. In control group, anthropometric measures and TC, TG, LDL-C increased, while HDL-C decreased. Conclusion: Prescribing ideal training course to help obese boys has not been recognized yet But, the finding in this research shows that periodic intence work out has a economic potential, and the efficiency of training Protocol for overweight and obese people, especially children and adolescents. Aim: Obesity and overweight along with metabolic disorders associated with them is one of the very important concerns in today’s world. According to the fact that chihdren and adolencrs bodies are in asensetive stage of growth and preparation for aduhthood, we aim to review the effects of high intensity interval training over the course of 12 weeks on testosterone, cortisol and lipids profiles levels in obese and overweight. Method: In this study 20 boys were selected based on per- post test in to control and high intensity interval training (HIIT) groups.Anthropometric measures, maximal aerobic speed (MAS), cortisol and testosterone levels, and lipid profile were measured in all subjects before and after training. Training group participated in a training program at 100 to 110% of MAS and 3 times per week during 12 weeks. Independent t-test and Paired t-test with a significance level of (P≤0/05) was used to analysis variables. Results: Following the training program, in training group, anthropometric measures including weight, BMI, percentage body fat and waist-hips ratio and cortisol resting level, TC, TG, LDL-C decreased, and HDL-C increased but no effect on testostron resting levels. In control group, anthropometric measures and TC, TG, LDL-C increased, while HDL-C decreased. Conclusion: Prescribing ideal training course to help obese boys has not been recognized yet But, the finding in this research shows that periodic intence work out has a economic potential, and the efficiency of training Protocol for overweight and obese people, especially children and adolescents.

https://jme.guilan.ac.ir/article_1694_4cfc48a0a6a9754e243398a8d50a41d3.pdf

University of Guilan Metabolism and Exercise 2322-2867 5 1 2015 05 22 The Effect of Resistance Training and Coriandrum sativum extract on oxidative stress indices in Diabetic Rats The Effect of Resistance Training and Coriandrum sativum extract on oxidative stress indices in Diabetic Rats 59 68 1695 FA Ahmad Abdi Assistace professor, Islamic Azad Universit Ayatollah Amoli Nasrin Ramezani PhD student in Exercise Physiology Hasan Haji Msc student in Exercise Physiology Journal Article 2015 08 08 Aim: Oxidative stress is an affective factor in insulin resistant, diabetes and other problems increasing blood glucose that seen in type 1 and 2 diabetes is an effective factor in producing oxidative stress. The aim of this study was to evaluate the effect of resistance training and Coriandrum sativum on oxidative stress factors in diabetic male rats. Method: The present experimental study was conducted on 40 adult male rats. After induction of diabetes, the rats were randomly divided into four equal groups (1: resistance training, 2: resistance training-Coriandrum sativum extract, 3: Coriandrum sativum extract, and 4: control). Diabetic condition was induced by using 55 mg af streptozotosin per one kg body weight. Then they performed 6 weeks of resistance training (five days a week for 6 weeks and with intensity of 30-100% rats weight) and drank oral Coriandrum sativum extract (150 mg/kg daily). After 6 weeks serum levels of total antioxidant capacity (TAC), superoxide dismutase (SOD) and catalase (CAT) were measured. Results: The results showed that resistance training alonge with Coriandrum sativum extract increased serum levels of TAC, SOD and CAT (p<0.05) significantly. Also, TAC level was increased in resistance and Coriandrum sativum extract groups (p<0.05). Conclusion: It seems that six weeks at resistance training combined with Coriandrum sativum extract may have a positive effect on body anti-oxidant system and treatment of diabetes. Aim: Oxidative stress is an affective factor in insulin resistant, diabetes and other problems increasing blood glucose that seen in type 1 and 2 diabetes is an effective factor in producing oxidative stress. The aim of this study was to evaluate the effect of resistance training and Coriandrum sativum on oxidative stress factors in diabetic male rats. Method: The present experimental study was conducted on 40 adult male rats. After induction of diabetes, the rats were randomly divided into four equal groups (1: resistance training, 2: resistance training-Coriandrum sativum extract, 3: Coriandrum sativum extract, and 4: control). Diabetic condition was induced by using 55 mg af streptozotosin per one kg body weight. Then they performed 6 weeks of resistance training (five days a week for 6 weeks and with intensity of 30-100% rats weight) and drank oral Coriandrum sativum extract (150 mg/kg daily). After 6 weeks serum levels of total antioxidant capacity (TAC), superoxide dismutase (SOD) and catalase (CAT) were measured. Results: The results showed that resistance training alonge with Coriandrum sativum extract increased serum levels of TAC, SOD and CAT (p<0.05) significantly. Also, TAC level was increased in resistance and Coriandrum sativum extract groups (p<0.05). Conclusion: It seems that six weeks at resistance training combined with Coriandrum sativum extract may have a positive effect on body anti-oxidant system and treatment of diabetes.

https://jme.guilan.ac.ir/article_1695_1f35a7576f0c1fb25201389be552566e.pdf

University of Guilan Metabolism and Exercise 2322-2867 5 1 2015 05 22 The effects of time of competition on proteinuria, hematuria and recovery in men Kong Fu players The effects of time of competition on proteinuria, hematuria and recovery in men Kong Fu players 69 80 1696 FA Amir Abas Monazzami Assistace professor, Razi University Zinab Mohammadi MSc in Exercise Physiology Rahman Soori Associate professor, University of Tehran Journal Article 2015 03 06 Aim: The purpose of this study was to determine the effects of time of competition on proteinuria , hematuria and recovery in men Kung fu players. Method: 28 men Kung fu players with at least 8 years of practice experience were selected and classified in two groups, randomly. Urine samples were taken 30 minutes before the competition, 60 minutes, 8 and 24 hours after competition from both groups. Dipsticks and total pro urine/CSF techniques were used for analyzing hematuria and proteinuria. To determine the difference between variables , one-way analysis of variance with repeated measures, paired t-test and independent t-test at the level of PResults: Results showed that there was no significant difference in Hematuria in the morning and evening Samples. The results also showed that there wes significant difference only in Proteinuria between two groups at 8 hours after competition (P<0.05) and there was no significant differencein Hematuria at times of 60 minutes, 8 and 24 hours after competition. Conclusion: Results showed that the time of recovery for Hematuria and Proteinuria is achieved faster in the evening than in the morning. As a result, playing matches in the morning requires efficient recovery strategies. Aim: The purpose of this study was to determine the effects of time of competition on proteinuria , hematuria and recovery in men Kung fu players. Method: 28 men Kung fu players with at least 8 years of practice experience were selected and classified in two groups, randomly. Urine samples were taken 30 minutes before the competition, 60 minutes, 8 and 24 hours after competition from both groups. Dipsticks and total pro urine/CSF techniques were used for analyzing hematuria and proteinuria. To determine the difference between variables , one-way analysis of variance with repeated measures, paired t-test and independent t-test at the level of PResults: Results showed that there was no significant difference in Hematuria in the morning and evening Samples. The results also showed that there wes significant difference only in Proteinuria between two groups at 8 hours after competition (P<0.05) and there was no significant differencein Hematuria at times of 60 minutes, 8 and 24 hours after competition. Conclusion: Results showed that the time of recovery for Hematuria and Proteinuria is achieved faster in the evening than in the morning. As a result, playing matches in the morning requires efficient recovery strategies.

https://jme.guilan.ac.ir/article_1696_08ae7e4daf4af39a020f098d272eaaa6.pdf