A Khodamoradi; E Talebi Garakani; F Mir Mohammad Rezaei; R Fathi
Abstract
Aim: Excessed energy is stored as triacylglycerol (TAG) in adipose tissue within various organs. In order to reduce excessed fat storage, the utilization of fat storage must be increased to produce energy. The purpose of this study was to evaluate the effects of 8 weeks progressive resistance training ...
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Aim: Excessed energy is stored as triacylglycerol (TAG) in adipose tissue within various organs. In order to reduce excessed fat storage, the utilization of fat storage must be increased to produce energy. The purpose of this study was to evaluate the effects of 8 weeks progressive resistance training on expression of proteins involved in skeletal muscle tissue lipolysis in rats feed with sucrose solution. Method: 32 male Wistar rats (6-8 weeks) were randomly divided into two groups, the first group took sucrose solution 30%, the second group did not. After 4 weeks, each group divided into exercise and control groups. Exercise groups performed a progressive resistance training protocol 3 days per week for 8 weeks. Tissue samples were taken 2 days after the last session. HSL, Perilipin and LXRα protein expression were determined by Western blot. To evaluate the difference between the variable and the interaction between them, two-way ANOVA at the significant level of P˂0.05 was used. Results: Protein levels of HSL and Perilipin were increased in the exercise group compared to control (P˂0.001), but LXRα levels were unchanged. The effect of sucrose solution alone and the interaction between the consumption of sucrose and progressive resistance training on the expression of these proteins in muscle tissue were not significant. Conclusion: The results show that although the 8 weeks of progressive resistance training significantly increased the expression of some proteins involved in lipolysis, but these changes are not related to the consumption of sucrose solution.
A Khosravi; R Fathi; M Baghersalimi; A Rasouli
Abstract
Aim: Angiopoietin-like protein 8 (ANGPTL8) is a hepatocyte-derived circulating factor that regulates plasma triglycerides levels. The purpose of this study was to investigate the response of serum ANGPTL8 levels to acute exercise in physically active young men..
Method: Eleven healthy, active young ...
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Aim: Angiopoietin-like protein 8 (ANGPTL8) is a hepatocyte-derived circulating factor that regulates plasma triglycerides levels. The purpose of this study was to investigate the response of serum ANGPTL8 levels to acute exercise in physically active young men..
Method: Eleven healthy, active young males (aged 24±3.63 years, BMI 22.98±2 kg/m2) volunteered for this study. Acute exercise protocol comprising 2 series of 6×10 s sprinting cycling with maximal effort and 10 min active rest (cycling with intensity 65%–75% HRmax).Blood samples were obtained at fasting state, pre-exercise (30 min after breakfast ~365 kcal), immediately, 15, 30 and 45 min after exercise for measuring serum variables. The repeated measures of ANOVA and Bonferroni post-hoc test used to evaluate changes of parameters in the different times. The relationship between variables was assessed using the Pearson correlation coefficient.
Results: The results of present study showed that ANGPTL8, glucose, insulin, lactate, TG and LDL-C levels significantly changed in any time courses of this study (p<0.05). At fasting state, 30 min after breakfast (before exercise) and post-exercise, ANGPTL8 levels not correlated with glucose, insulin, lactate, TG, TC, HDL-C and LDL-C. There was no significant relationship between ANGPTL8 and weight, BMI and body fat percentage.
Conclusion: It seems that acute and short-term exercise is make significant changes in serum levels of ANGPTL8. On the other hand no significant relationship between ANGPTL8 and body composition may related to indvisual differences.
