َAkram Arzani; Sadmehr Mirdar; Mehdi Hedayati
Volume 4, Issue 2 , December 2015, , Pages 151-158
Abstract
Objective: The aquaporin5 (AQP5) is an integral membrane protein that plays an important role in maintaining water homeostasis in the lung. The purpose of this study was to evaluate the effect of interval training on AQP5 levels in the lung of Male Wistar rats during puberty. Methodology: 30 three-week ...
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Objective: The aquaporin5 (AQP5) is an integral membrane protein that plays an important role in maintaining water homeostasis in the lung. The purpose of this study was to evaluate the effect of interval training on AQP5 levels in the lung of Male Wistar rats during puberty. Methodology: 30 three-week male Wistar rats with average weight of 68±9 g were randomly divided into three groups included; the base, control and training groups. The training group ran on treadmill for 6 weeks (6 per week, 30 minutes each session at a speed of 15 to70 meters per minute). AQP5 levels were measured by ELISA methods. Analyzed is done with two-way ANOVA and LSD test at PResults: Results showed significant differences between AQP5 levels of control, base and training groups (P<0.05). While, there were no significant differencesbetween AQP5 levels of control and base groups . Furthermore, six-weeks interval training increased AQP5 levels of lung tissue in exercise group compared to the control group by 229.03 and 284.9 percent. Conclusion: It seems that an Increased interval training can improve the of epithelial cell performance and protect the AQP5 level changes during the puberty, and improve lung liquid homeostasis.
Zinab Gurgin; Reza Gharakhanlou; Abdolhosin Parnow; Somayeh Rajabi; Mehdi Hedayati
Volume 1, Issue 1 , April 2011, , Pages 1-10
Abstract
Abstract Aim: Nicotinic acetylcholine receptors (nAChRs) are integral membrane proteins and prototypic members of the ligand-gated ion-channel super-family. The Purpose of the present study was to investigate the effect of endurance, resistance and concurrent training on the content of nAChR in fast ...
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Abstract Aim: Nicotinic acetylcholine receptors (nAChRs) are integral membrane proteins and prototypic members of the ligand-gated ion-channel super-family. The Purpose of the present study was to investigate the effect of endurance, resistance and concurrent training on the content of nAChR in fast skeletal muscles of male Wistar rats.
Method: Thirty male Wistar rats (220±15 gr) randomly were divided to four groups and followed 12 weeks of training according to the protocols. Animals of the endurance training group were exercised on treadmill for 12 weeks, 5 times a week, and 60 minutes a day at velocities up to 30 m/min. Animals of the Resistance group were housed in metal cage with a 2m high wire-mesh tower, with water bottles set at the top. Concurrent training group did both resistance and endurance trainings. Forty-eight hours after last session of protocols, animals were anaesthetized and the tibialis anterior (AT) was removed. For nAChR assay and for data analysis, ANOVA and independent- samples t- test were used.
Results: Data analysis showed that fast muscle nAChR content significantly difference between endurance, resistance and concurrent training groups with control group (P
