Afshar Jafari; Alireza Rostami; Vahid Sari-Sarraf
Volume 2, Issue 1 , April 2012
Abstract
Abstract
Aim: The aim of this study was to determin the effect of short-term Coenzyme Q10 supplementation on plasma lactate and serum total creatine kinase (CK) in healthy collegiate ...
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Abstract
Aim: The aim of this study was to determin the effect of short-term Coenzyme Q10 supplementation on plasma lactate and serum total creatine kinase (CK) in healthy collegiate men after an aerobic exercise.
Method: Eighteen healthy untrained men (age 24±3 years, body fat 12±2%, and VO2max 39±3 ml/kg/min) in a randomized and double-blind design were allocated in two equal groups: supplement group (n=9, Coenzyme Q10: 2.5 mg/kg/day) and placebo group (n=9, Dextrose: 2.5 mg/kg/day). After supplementation period, all subjects were participated in aerobic exercise protocol with 75% VO2max on the treadmill for 30 minutes. Blood samples obtained before the Q10 supplementation along with immediately before and after the exercise protocol, respectively. Plasma lactate and serum total creatine kinase were determined by automatic analyzers. Data were analyzed by repeated measure ANOVA, Bonferroni and independent t test at P≤0.05.
Results: The results show that short-term Coenzyme Q10 supplementation has no significant effect on basal parameters. However, plasma lactate and serum total CK were significantly increased (P
