Masoud Shakki; Fatemeh Hosseini; Saeed Ghorbani; reza rezai shirazi; H parsian
Abstract
Aim: The purpose of the study was to investigate the effect of 8 weeks of aerobic interval exercise with silymarin supplementation on antioxidant, liver damage and atherogenic indicators in male Wistar rats fed a high-fat diet.Methods: This experimental study with laboratory method was performed on 35 ...
Read More
Aim: The purpose of the study was to investigate the effect of 8 weeks of aerobic interval exercise with silymarin supplementation on antioxidant, liver damage and atherogenic indicators in male Wistar rats fed a high-fat diet.Methods: This experimental study with laboratory method was performed on 35 male Wistar rats with a body weight of 160.45±7.08g and 3-weeks-of-age were randomly divided into 5 groups consisted of ordinary diet control (ODC), fatty diet control (FDC), fatty diet with supplement (FDS), fatty diet with exercise (FDE), fatty diet with supplement and exercise (FDSE). The exercises included the running on treadmill for 8 weeks, five times/week and 30 minutes in an exercise session. Silymarin supplementation with dose of 140 mg/kg/day of body, weight was received for two weeks. Liver tissue and samples were obtained after 48 hours of the last diet and data analyzed. Results: Significant decrease in FDSE and FDE groups compared with FDC group in ALT, AST, and ALP, MDA, TC and TG variables were observed. Whereas, there were significantly increased in FDSE group compared with FDC in SOD and HDL-C variables. Also, LDL-C and AIP in FDSE group compared with FDC had shown a significant decrease (p> .05).Conclusion: The applying of aerobic interval exercise alone or with silymarin supplementation reduced the risk to NAFLD such as enzymes involved and atherogenic index in male Wistar rats fed a high-fat diet; therefore, it could probably improve the disease through increase the antioxidant capacity and reduce blood lipid profiles.
Reza Rezaee Shirazi; Fatemeh Hossini
Volume 3, Issue 1 , April 2013, , Pages 47-58
Abstract
Abstract
Aim: The purpose of the study was to compare the effect of eight weeks of continuous and intermittent aerobic training on Visfatin and insulin resistance plasma levels in 17-25 years obese males.
Method: Fifty participants (age: 22.05±3.9 years; weight: 89.85±12.8 kg; height: 176.7±10.09 ...
Read More
Abstract
Aim: The purpose of the study was to compare the effect of eight weeks of continuous and intermittent aerobic training on Visfatin and insulin resistance plasma levels in 17-25 years obese males.
Method: Fifty participants (age: 22.05±3.9 years; weight: 89.85±12.8 kg; height: 176.7±10.09 cm) were randomly divided into continuous and intermittent aerobic groups. The continuous aerobic group performed the training protocol with 60 to 80 percent of Vo2max and the intermittent aerobic group with 55 to 85 percent of Vo2max for 60 minutes in session, 5 days per week. Fasting plasma Visfatin and insulin levels were measured by ELISA and fasting plasma glucose was measured by a enzymatic method. Insulin resistance was determined by HOMA-IR formula. The significance of the effects of training were assessed by the dependent t-test and post-test significance between groups was assessed using the independent t-test (P≤0.05).
Results: Findings have shown that the eight weeks of continuous aerobic training significantly decreased visfatin plasma levels and insulin resistance resting levels (P≤0.05), and the eight weeks of intermittent aerobic training were significantly decreased in visfatin plasma levels (P≤0.05) and insulin resistance resting levels (P≤0.05), but there was no significant decrease between post-tests in visfatin plasma levels and insulin resistance resting levels.
Conclusion: The eight-week continuous and intermittent aerobic training programs may effect to reduce visfatin plasma level and insulin resistance resting that related to decrease of body mass index.
Key words: Exercise, Glucose, Fasting insulin, Visceral fat.
