Hormonal and enzymatic functions in exercise
Javad Vakili; Saeed Nikookheslat; Mohammad Tanhaei; maryam akbari
Abstract
Objective: Training with blood flow restriction likely have a profound effect on growth related hormonal indices. The purpose of this study was to determine the effect of two weeks intermittent training with and without blood flow restriction on serum levels of growth hormone, IGF-1 and Lactate in amateur ...
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Objective: Training with blood flow restriction likely have a profound effect on growth related hormonal indices. The purpose of this study was to determine the effect of two weeks intermittent training with and without blood flow restriction on serum levels of growth hormone, IGF-1 and Lactate in amateur adolescent football players. Methodology: Therefor 24 amateur adolescent football players with age of 17/79±0/79 years-old, height of 175/41 ± 3/37 cm and weight of 69/12±4/49 kg were voluntarily selected and divided based on VO2max into two groups of control and experimental groups. The training protocol was performed in treadmill with intensity of 60-75% MHR, four sessions per week, in 400 meters, three sets in first week and four sets in second week. Recovery intervals was 60-80 seconds between exercise intervals. The thigh cuff pressure was set between 140 and 180 mmHg. Blood samples were gathered in two phases before of training protocol and 48h after last session of training for analyses of serum GH, IGF-1 levels and lactate immediately after the RAST anaerobic test. Independent and dependent T-test was used for data analyzing and significant level was set at p<0/05. Results: There was a significant increase in serum GH (p=0/016) and lactate (p=0/000) in BFR group. But there weren’t any difference between two group in serum IGF-1 after BFR and nonBFR training (P >0/05).Conclusion: it is concluded that intermittent trainings with BFR probably be more effective in enhancing adolescent’s growth indicators than intermittent training.
Z Shanazari; M Faramarzi; E Banitalebi; R Hemmati
Abstract
Aim: One of the most important and prevalent disorders in elderly people is age-related muscular atrophy or Sarcopenia. Sarcopenia is associated with a significant reduction in muscle strength and volume. The purpose of this study was to investigate the effect of moderate and high intensity resistance ...
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Aim: One of the most important and prevalent disorders in elderly people is age-related muscular atrophy or Sarcopenia. Sarcopenia is associated with a significant reduction in muscle strength and volume. The purpose of this study was to investigate the effect of moderate and high intensity resistance training on serum levels of myostatin and IGF-1 in elderly rats Method: thirty male Wistar rats (23 months old) were randomly divided into two experimental and control group including moderate intensity resistance training (n = 10), high intensity resistance training (n = 10) and the control group (n = 10). Resistance training included 8 weeks of climbing a ladder with high intensity (80% MVCC) and moderate intensity (60% of MVCC) and 5 days a week. After completing training, serum concentration of IGF-1 and myostatin were measured using the ELISA method. Results: Myostatin concentration in decreased in high (916.5±43.1) and moderate (958.8±36.9) intensity resistance groups and IGF-1 increases in high (156.3±15.5) and moderate (141.8±7.4) intensity resistance groups (p<0.05). Also, there was significant difference between the IGF-I levels in high and moderate resistance training (p=0.009). However, there was no significant difference in myostatin level between groups. Conclusion: It seems that resistance training with moderate and high intensity can be change the resting levels of factors associated with muscular atrophy in elderly rats. However, there id further need to evaluate in human participants.
