Maryam Ebrahimi
Abstract
Objective: in this research, levels of metabolic enzymes, pyruvate dehydrogenase kinase 4 (PDK-4) and carnitine palmitoyltransferase 1 (CPT-1) and their relationship with blood glucose, lactate and lipid profile were studied in response to a single bout of Crossfit exercise in fasting and fed state.Methods: ...
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Objective: in this research, levels of metabolic enzymes, pyruvate dehydrogenase kinase 4 (PDK-4) and carnitine palmitoyltransferase 1 (CPT-1) and their relationship with blood glucose, lactate and lipid profile were studied in response to a single bout of Crossfit exercise in fasting and fed state.Methods: 23 healthy female sport science students with minimum of 3 years regular training were randomly assigned into fast control, fed control, fast Crossfit and fed Crossfit groups. At the end of the session, rating of perceived exertion was estimated by OMNI scale and blood samples were collected. Two-way analysis of variances and Pearson test were used at the alpha level .05 in SPSS 22. Results: glucose, TG, cholesterol, LDL, HDL, PDK-4 and CPT-1 mean levels had not any significant differences between groups (P > .05). Plasma lactate level was higher in Crossfit groups compared to controls (P = .045). Serum PDK-4 was positively correlated with CPT-1 (r = .550, P = .007) and negatively correlated with lactate levels (r = .600, P = .003). Conclusion: fasting and feeding had not any effect on metabolic indices, nor in resting neither after exercise. Higher lactate levels after Crossfit exercise and no difference in PDK-4 and CPT-1 compared with resting, probably suggest more contribution of glucose for energy production via aerobic and anaerobic pathways in this protocol.