Physical activity, weight control and obesity
Sana Shurehkandi; MOSTAFA Khani; Elaheh Piralaiy; mahdi faramoushi
Abstract
Aim: Adipose tissue, as a metabolically active tissue, plays an important role in increasing inflammatory indices. So, the aim of this study was to investigate the effect of two-week high intensity interval training (HIIT) with thyme extract supplementation on some inflammatory and anthropometric markers ...
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Aim: Adipose tissue, as a metabolically active tissue, plays an important role in increasing inflammatory indices. So, the aim of this study was to investigate the effect of two-week high intensity interval training (HIIT) with thyme extract supplementation on some inflammatory and anthropometric markers in Tabriz city obese and overweight women. Methods: The current research was a semi-experimental study, and its statistical population consisted of overweight and obese women. To investigate CRP, ESR, TNF-α, quality of life, and body composition, 40 people were selected voluntarily with an average age of 33.07 ± 4.79, weight 76.76 ± 5.63, and body profile 29.02 ± 1.74, and were randomly divided into four homogenous groups (10 people in each group): training, supplement, training+supplement group and placebo. HIIT was performed for two weeks with 80-95% of HRR and Azarbaijani thyme was used as a supplement in two times a day. The data was analyzed using analysis of covariance test in the significance level of 0.05. Findings: The results showed that there is a significant difference in CRP (F=15, P=0.0001), TNF-α (F=25.56, P=0.0001), ESR (F=47.7, P=0.0001) , BMI (F = 20.71, P = 0.01) and WHR (F = 10.16, P = 0.01) between groups.. But there was no significant difference in calf circumference (F = 0.56, P = 0.64). Conclusion: Short-term HIIT alone or in combination with thyme reduces inflammation (CRP, ESR and TNF-α) and improve some anthropometric indicies in obese and overweight women.
Faegheh Khosh-khahesh; Marefat Siahkohian; Babak Nokhostin Rohi
Volume 1, Issue 1 , April 2011, , Pages 23-32
Abstract
AbstractAim: The purpose of this study was to examine the effect of acute celecoxib administration on exercise-induced inflammation and lipid peroxidation markers.
Method: Twenty untrained, healthy male (age; 25.5±4.5 yr, weight; 72.8±7.9 kg, height; 177.3± 7.2 cm) were randomly assigned to treatment ...
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AbstractAim: The purpose of this study was to examine the effect of acute celecoxib administration on exercise-induced inflammation and lipid peroxidation markers.
Method: Twenty untrained, healthy male (age; 25.5±4.5 yr, weight; 72.8±7.9 kg, height; 177.3± 7.2 cm) were randomly assigned to treatment (T) and placebo (P) groups. Blood samples were taken before, immediately, 3h and 24h after exercise. Subjects ran for 30 minutes with 75% VO2max on treadmill and 100 mg celecoxib and placebo administrated immediately and 12h after the second blood sampling to T and P groups respectively. White blood cells (WBC) and creatine kinas (CK) were measured by an autoanalyzer and malondealdehyde (MDA) by HPLC. Data were analyzed using repeated measures analysis of variance (ANOVA) with bonferoni correction and unpaired t-test.
Results: WBC levels were significantly increased 3h and decreased 24h after exercise in both groups (P≤0.05), while there was no difference between the two groups, though WBC levels were lower 24h after exercise in the T group than P group. CK levels were significantly increased immediately, 3h and 24h after exercise in both groups (P≤0.05), but there was no difference between the two groups, though CK levels were increased 24h after exercise in the T group than P group. MDA levels were significantly increased immediately after exercise in both groups (P≤0.05) but there was no difference between the two groups, though MDA levels were increased 24h after exercise in T group than P group.
Conclusion: Acute celecoxib administration could not affect inflammation and oxidative stress markers.Key words: Celecoxib, Lipid peroxidation, Inflammation
