Sports and health nutrition
Fatemeh Kazeminasab
Abstract
Background: The exercise training and vegetarian diets have been accepted as a suitable and non-pharmacological method to improve lifestyle and reduce metabolic diseases, including diabetes and metabolic syndrome. The aim of this study was to investigate the combined effect of aerobic exercise and vegetarian ...
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Background: The exercise training and vegetarian diets have been accepted as a suitable and non-pharmacological method to improve lifestyle and reduce metabolic diseases, including diabetes and metabolic syndrome. The aim of this study was to investigate the combined effect of aerobic exercise and vegetarian diet on insulin resistance factors.Methods: The PubMed, Web of Science, SID, Magiran, and Google scholar databases were searched until February 2022 for English articles. Meta-analyses were performed to compare the impact of aerobic exercise and vegetarian diet on insulin resistance factors (fasting glucose, insulin, and HOMA-IR). Standardized mean differences (SMD), weighted mean differences (WMD), and 95% confidence interval (CI) were calculated using random and fixed effect models. Also, the I2 test was used to determine heterogeneity, and the Funnel plot and Egger tests at a significant level of 0.1 were used to determine publication bias.Results: The results of meta-analysis of 29 studies with 10019 adults, showed that aerobic exercise and vegetarian diet significantly decreased in body weight [WMD=-4.49, (CI: -6.27 to -2.72), p=0.001], fasting serum glucose [SMD=-0.46, (CI: -0.65 to -0.27), p=0.001], serum insulin [SMD=-0.42, (CI: -0.52 to -0.32), p=0.001], and HOMA-IR [WMD=-0.73, (CI: -0.97 to -0.49), p=0.001].Conclusion: The findings of the present meta-analysis show the important role of exercise and vegetarian diet in improving insulin resistance. So, aerobic exercise and vegetarian diet are suggested as a non-drug approach for reducing fasting insulin and glucose for adults.
AA Gaeini; N Ramezani; L Shafiei Neek
Abstract
Aim: Background: The liver xα receptor (LXRα) participates in glucose metabolism. On the other hand, glucose transfer in liver by glucose transporter 2 (GLUT2). Therefore, this study was designed to examine the changes of LXRα, GLUT2 genes expression in liver and insulin resistance ...
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Aim: Background: The liver xα receptor (LXRα) participates in glucose metabolism. On the other hand, glucose transfer in liver by glucose transporter 2 (GLUT2). Therefore, this study was designed to examine the changes of LXRα, GLUT2 genes expression in liver and insulin resistance after 8 weeks of aerobic training in type 2 diabetic rats. Method: Eighteen male 8-weeks-old Wistar rats were selected as research sample. Diabetes was induced by nicotinamide and streptozotocin. Five days after diabetes induction, fasting blood glucose was measured using blood glucose strips. Rats with fasting blood glucose between 126-400 mg were selected as diabetic. Rats were divided into two groups: control and training. The training program was running with the speed of 10–25 m/min for 15-40 min/day, 5% slope, 5 days a week for 8 weeks. Results: Diabetes induction resulted in significant increase in body weight (p=0.001). Training group had higher muscle weight (p=0.001) and HbA1c (p=0.001) but lower glucose (p=0. 001), insulin (p=0.002) and insulin resistance index (p=0.002). LXRα and GLUT2 gene expressions were not different significantly. Conclusion: It seems that 8 weeks aerobic training with 60-80% of vo2max can induce some positive metabolic changes in diabetic rats but did not induce any significant changes in LXRα and GLUT2 genes expression in liver tissue.
A Khosravi; R Fathi; M Baghersalimi; A Rasouli
Abstract
Aim: Angiopoietin-like protein 8 (ANGPTL8) is a hepatocyte-derived circulating factor that regulates plasma triglycerides levels. The purpose of this study was to investigate the response of serum ANGPTL8 levels to acute exercise in physically active young men..
Method: Eleven healthy, active young ...
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Aim: Angiopoietin-like protein 8 (ANGPTL8) is a hepatocyte-derived circulating factor that regulates plasma triglycerides levels. The purpose of this study was to investigate the response of serum ANGPTL8 levels to acute exercise in physically active young men..
Method: Eleven healthy, active young males (aged 24±3.63 years, BMI 22.98±2 kg/m2) volunteered for this study. Acute exercise protocol comprising 2 series of 6×10 s sprinting cycling with maximal effort and 10 min active rest (cycling with intensity 65%–75% HRmax).Blood samples were obtained at fasting state, pre-exercise (30 min after breakfast ~365 kcal), immediately, 15, 30 and 45 min after exercise for measuring serum variables. The repeated measures of ANOVA and Bonferroni post-hoc test used to evaluate changes of parameters in the different times. The relationship between variables was assessed using the Pearson correlation coefficient.
Results: The results of present study showed that ANGPTL8, glucose, insulin, lactate, TG and LDL-C levels significantly changed in any time courses of this study (p<0.05). At fasting state, 30 min after breakfast (before exercise) and post-exercise, ANGPTL8 levels not correlated with glucose, insulin, lactate, TG, TC, HDL-C and LDL-C. There was no significant relationship between ANGPTL8 and weight, BMI and body fat percentage.
Conclusion: It seems that acute and short-term exercise is make significant changes in serum levels of ANGPTL8. On the other hand no significant relationship between ANGPTL8 and body composition may related to indvisual differences.
J Mehrabani; O Khoshkhoui
Abstract
Aim: Systemic inflammation is one of the important consequences of the intensive physical exercises that can lead to decline in performance, same as leading to disorder of cell metabolism and inflammation acute phase responses. probably immune booster supplements can be effective in improving these functions. ...
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Aim: Systemic inflammation is one of the important consequences of the intensive physical exercises that can lead to decline in performance, same as leading to disorder of cell metabolism and inflammation acute phase responses. probably immune booster supplements can be effective in improving these functions. The present study assessing the effects of a treadmill exhaustive exercise after taking Glutamine on level of glucose, insulin, hs-CRP WBC, lactate and fibrinogen among 19 young athletic men
Method: The participants were selected randomly and divided into two groups of Glutamine (n=9, age: 21.1±0.8yr; weight: 68.9±6.2kg) and placebo (n= 10, age: 20.9±0.6yr; weight: 66.9±6.8kg). Glutamine group received 16gr. Glutamine mixed in 50gr. sucrose (sugar), 1.5gr. lemon juice and 300ml water. The placebo group, on the other hand, received 300ml solution of 5% sucrose (i.e. 300ml and 5% sucrose (sugar) and 0.15% lemon juice. After 15min of rest, the participants took glutamine and placebo using double blind method and engaged in an exhaustive Bruce protocol after 1hr of rest.
Results: The results showed that blood hs-CRP level in the Glutamine group was not changed significantly comparing with that of placebo group immediately after exercise. Although, blood level of glucose, insulin and fibrinogen showed significant changes immediately after exercise between the Glutamine and placebo, and an increase immediately after exercise compared to pre-exercise (p<0.05).
Conclusion: Apparently, exercise and taking Glutamine influences on hs-CRP level; although, did not stop increase in glucose, insulin and fibrinogen after exhaustive exercise. It seems taking supplementary Glutamine, probably, can decrease blood level of CRP as a major acute phase response after an intense exercise.
Hamid Rajabi; Ehsan Soleymani Far; Shirin Hasani Ranjbar; Ramin Heshmat
Volume 1, Issue 1 , April 2011, , Pages 61-78
Abstract
AbstractAim: This study aimed to investigate the effects of intense resistance exercise on IGF-1 system and monitoring time course of changes in its components.Method: Nineteen healthy physical education students as trained group (age 22.21±1.44 years, height 178.41±6.39 cm, weight 73.47±7.86 kg) ...
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AbstractAim: This study aimed to investigate the effects of intense resistance exercise on IGF-1 system and monitoring time course of changes in its components.Method: Nineteen healthy physical education students as trained group (age 22.21±1.44 years, height 178.41±6.39 cm, weight 73.47±7.86 kg) and fifteen healthy nonphysical education students as untrained group (age 23.07±1.91 years, height 174.02±5.08 cm, weight 70.47±10.13 kg) volunteered to participate in this study and each group were randomly divided into two experimental and control groups. Experimental groups performed one session of resistance exercise with 70-80% 1RM. Blood sampling was done 4 times, 2-hours after breakfast (Pre-test), immediately (T2), 4- (T3) and 7-hours after the exercise (T4). Blood samples were analyzed by RIA method. Two-way repeated measure (ANOVA), Friedman and Kruskal-Walis tests were used to analyze data.Results: One session of resistance exercise was associated with a significant increase in GH at T2 (P
