Ameneh Pourrahim Ghouroughchi; Arsalan Damirchi; Parvin Babaei
Volume 4, Issue 2 , December 2015, , Pages 121-135
Abstract
Objective: The aim of this study was to investigate the effect of aerobic-resistance training on visceral adipose tissue, serum omentin-1 and insulin resistance in ovariectomized (OVX) rats. Methodology: Fifty Female Wistar rats (weight, 180±5g) were divided accidental and according body weight ...
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Objective: The aim of this study was to investigate the effect of aerobic-resistance training on visceral adipose tissue, serum omentin-1 and insulin resistance in ovariectomized (OVX) rats. Methodology: Fifty Female Wistar rats (weight, 180±5g) were divided accidental and according body weight into five groups: SHAM (n=20) and OVX (n=30) groups. OVX rats were subdivided into 2 Ovx+sedentary (Sedentary; n=20) groups and one aerobic-resistance training (Ovx+Exe; n=10) group. Two weeks after surgery, one group of OVX rats and one group of SHAM rats were sacrificed and omentin-1, insulin resistance and visceral fat were measured. The other OVX rats were randomly divided into the following subgroups: 1) OVX and sedentary (Sedentary); 2) OVX and Exercise (Ovx+Exe). The exercise consisted of 8 weeks of aerobic-resistance exercise (3 days/week, 20 m/min, 60 min/day, 10% slope, Load; 3% body weight, attached to tail), three days a week. After complete anesthesia, the abdominal cavity was rapidly opened and blood samples were collected. All intraabdominal fat were dissected out and weighed immediately. Omentin-1 was measured by rat omentin ELISA kit. HOMA-IR was used to estimate the insulin resistance. Results: There was no significant differences between weights means all groups. After two weeks of surgery, there was no significant difference between visceral fat, omentin-1 and HOMA-IR in SHAM2 compared to OVX2. After eight weeks, combined aerobic-resistance training in Ovx+Exe significantly decreased visceral fat gain induced via ovariectomy by 21/4% compared to the level observed in Sedentary; whereas, visceral fat significantly increased by 92.5% in OVX2 compared to SHAM2 (p<0.05). Omentin-1 increased in Ovx+Exe compared to Sedentary and SHAM, by56/5% and51/6%, respectively; whereas it was significantly decreased by3/1% in Sedentary compared to SHAM (p<0.05). HOMA-IR induced via ovariectomy significantly decreased by74.7% in Ovx+Exe compared to Sedentary; whereas, it significantly increased by 193.7% in OVX2 compared to SHAM2 (p<0/05). Also, HOMA-IR decreased in Ovx+Exe compared to SHAM2, but it was n ́t significant. Conclusion: 8 week aerobic-resistance training successfully decreased visceral fat and insulin resistance via increasing omentin-1. So, it seems that 8-week aerobic-resistance training with 70-85% Vo2max is suitable for controlling body weight gain, decreasing visceral fat and insulin resistance and increasing omentin-1 in menopause period.
Reza Rezaee Shirazi; Fatemeh Hossini
Volume 3, Issue 1 , April 2013, , Pages 47-58
Abstract
Abstract
Aim: The purpose of the study was to compare the effect of eight weeks of continuous and intermittent aerobic training on Visfatin and insulin resistance plasma levels in 17-25 years obese males.
Method: Fifty participants (age: 22.05±3.9 years; weight: 89.85±12.8 kg; height: 176.7±10.09 ...
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Abstract
Aim: The purpose of the study was to compare the effect of eight weeks of continuous and intermittent aerobic training on Visfatin and insulin resistance plasma levels in 17-25 years obese males.
Method: Fifty participants (age: 22.05±3.9 years; weight: 89.85±12.8 kg; height: 176.7±10.09 cm) were randomly divided into continuous and intermittent aerobic groups. The continuous aerobic group performed the training protocol with 60 to 80 percent of Vo2max and the intermittent aerobic group with 55 to 85 percent of Vo2max for 60 minutes in session, 5 days per week. Fasting plasma Visfatin and insulin levels were measured by ELISA and fasting plasma glucose was measured by a enzymatic method. Insulin resistance was determined by HOMA-IR formula. The significance of the effects of training were assessed by the dependent t-test and post-test significance between groups was assessed using the independent t-test (P≤0.05).
Results: Findings have shown that the eight weeks of continuous aerobic training significantly decreased visfatin plasma levels and insulin resistance resting levels (P≤0.05), and the eight weeks of intermittent aerobic training were significantly decreased in visfatin plasma levels (P≤0.05) and insulin resistance resting levels (P≤0.05), but there was no significant decrease between post-tests in visfatin plasma levels and insulin resistance resting levels.
Conclusion: The eight-week continuous and intermittent aerobic training programs may effect to reduce visfatin plasma level and insulin resistance resting that related to decrease of body mass index.
Key words: Exercise, Glucose, Fasting insulin, Visceral fat.
