R Fathi; M Baghersalimi; M Nazemi; A Khosravi
Abstract
Aim: Dipeptidyl-peptidase-4 (DPP-4) has been proposed as a bridge between obesity and insulin resistance (IR). The aim of this study was to investigate the changes in serum levels of DPP-4 and HOMA2-IR after eight weeks of interval and continuous-walking in 9-11 year-old obese girls. Method: thirty two-obese ...
Read More
Aim: Dipeptidyl-peptidase-4 (DPP-4) has been proposed as a bridge between obesity and insulin resistance (IR). The aim of this study was to investigate the changes in serum levels of DPP-4 and HOMA2-IR after eight weeks of interval and continuous-walking in 9-11 year-old obese girls. Method: thirty two-obese girls (age: 9.62±0.75 years and BMI-percentile: 97.38±1.40%) volunteered in this study and were assigned to interval (n=12), continuous (n=11) and control (n=9) groups. The training were performed for 8-weeks, 3-sessions per week (30-min walking in the continuous and interval groups with 60-75%HRmax and 70-85%HRmax, respectively). Interval-walking included 2-min of walking and 1-min of active rest. After 10-hours of fasting, blood sampling was performed before the beginning of training and 72-hours after the last session. The paired t-test was used to examine the within-group changes. Results: Eight weeks of continuous and interval training did not significantly change the levels of DPP-4, insulin, glucose, and HOMA2-IR compared to the control group. Compared to the control group, the interval training resulted in improvement of the body weight, BMI, and BMI percentile (p=0.004, p=0.019, p=0.022), while the BMI only tended to decrease in the continuous training group (p=0.077). Conclusion: It seems that the improvement of the body composition due to the protocol used in this study was not sufficient to make significant changes in the HOMA2-IR and DPP-4 in early-pubertal obese girls.
َAkram Arzani; Sadmehr Mirdar; Mehdi Hedayati
Volume 4, Issue 2 , December 2015, , Pages 151-158
Abstract
Objective: The aquaporin5 (AQP5) is an integral membrane protein that plays an important role in maintaining water homeostasis in the lung. The purpose of this study was to evaluate the effect of interval training on AQP5 levels in the lung of Male Wistar rats during puberty. Methodology: 30 three-week ...
Read More
Objective: The aquaporin5 (AQP5) is an integral membrane protein that plays an important role in maintaining water homeostasis in the lung. The purpose of this study was to evaluate the effect of interval training on AQP5 levels in the lung of Male Wistar rats during puberty. Methodology: 30 three-week male Wistar rats with average weight of 68±9 g were randomly divided into three groups included; the base, control and training groups. The training group ran on treadmill for 6 weeks (6 per week, 30 minutes each session at a speed of 15 to70 meters per minute). AQP5 levels were measured by ELISA methods. Analyzed is done with two-way ANOVA and LSD test at PResults: Results showed significant differences between AQP5 levels of control, base and training groups (P<0.05). While, there were no significant differencesbetween AQP5 levels of control and base groups . Furthermore, six-weeks interval training increased AQP5 levels of lung tissue in exercise group compared to the control group by 229.03 and 284.9 percent. Conclusion: It seems that an Increased interval training can improve the of epithelial cell performance and protect the AQP5 level changes during the puberty, and improve lung liquid homeostasis.