Exercise Physiology
maryam Molaei Jeghanab; mandana gholami; Abdolali Banaeifar; Farshad Ghazalian
Abstract
Aim: Changes in adipokines levels play an important role in the development of different disorders including the type 2 diabetes, which among them, chemerin and omentin-1 attracted a lotof attention. In contrast, positive effect of exercise training and vitaminD consumption have been reported in combating ...
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Aim: Changes in adipokines levels play an important role in the development of different disorders including the type 2 diabetes, which among them, chemerin and omentin-1 attracted a lotof attention. In contrast, positive effect of exercise training and vitaminD consumption have been reported in combating with pathologic effects of type 2 diabetes. The aim of present study is to determine the effect of eight weeks resistance training along withvitaminD consumption on levels of chemerin and omentin-1 in type 2 diabetic patientsMethod: 40 diabetics men with average age of 47.19±3.83 years old and body fat percentage 30.96±2.49 assigned in four groups including the placebo, vitaminD, training and training+ vitaminD groups. The resistance training program conducted for eight weeks and three session per week with 60 to 70 percent of 1RM intensity. VitaminD consumption considered daily 2000 iu and placebo (oral paraffin) ingestion considered in the same amount. At the baseline and ending intervention, blood samples collected and the levels of chemerin and omentin-1 were measured and insulin resistance calculated. Data were analyzed by analysis of covariance test and Bonferroni post-hoc test.Results: The present study findings indicated that in training and training+vitaminD groups the chemerin levels significantly decreased and omentin-1 significantly increased (p<0.05). Moreover, significant decrease of insulin resistance was observed in training and training+vitaminD groups (p<0.05).Conclusion: VitaminD ingestion can increase the hypoglycemic effects of resistance training partly, which these positive effects of resistance training and vitaminD consumption exerted by increase in omentin1 levels and decrease of chemerin levels.
Ameneh Pourrahim Ghouroughchi; Arsalan Damirchi; Parvin Babaei
Volume 4, Issue 2 , December 2015, , Pages 121-135
Abstract
Objective: The aim of this study was to investigate the effect of aerobic-resistance training on visceral adipose tissue, serum omentin-1 and insulin resistance in ovariectomized (OVX) rats. Methodology: Fifty Female Wistar rats (weight, 180±5g) were divided accidental and according body weight ...
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Objective: The aim of this study was to investigate the effect of aerobic-resistance training on visceral adipose tissue, serum omentin-1 and insulin resistance in ovariectomized (OVX) rats. Methodology: Fifty Female Wistar rats (weight, 180±5g) were divided accidental and according body weight into five groups: SHAM (n=20) and OVX (n=30) groups. OVX rats were subdivided into 2 Ovx+sedentary (Sedentary; n=20) groups and one aerobic-resistance training (Ovx+Exe; n=10) group. Two weeks after surgery, one group of OVX rats and one group of SHAM rats were sacrificed and omentin-1, insulin resistance and visceral fat were measured. The other OVX rats were randomly divided into the following subgroups: 1) OVX and sedentary (Sedentary); 2) OVX and Exercise (Ovx+Exe). The exercise consisted of 8 weeks of aerobic-resistance exercise (3 days/week, 20 m/min, 60 min/day, 10% slope, Load; 3% body weight, attached to tail), three days a week. After complete anesthesia, the abdominal cavity was rapidly opened and blood samples were collected. All intraabdominal fat were dissected out and weighed immediately. Omentin-1 was measured by rat omentin ELISA kit. HOMA-IR was used to estimate the insulin resistance. Results: There was no significant differences between weights means all groups. After two weeks of surgery, there was no significant difference between visceral fat, omentin-1 and HOMA-IR in SHAM2 compared to OVX2. After eight weeks, combined aerobic-resistance training in Ovx+Exe significantly decreased visceral fat gain induced via ovariectomy by 21/4% compared to the level observed in Sedentary; whereas, visceral fat significantly increased by 92.5% in OVX2 compared to SHAM2 (p<0.05). Omentin-1 increased in Ovx+Exe compared to Sedentary and SHAM, by56/5% and51/6%, respectively; whereas it was significantly decreased by3/1% in Sedentary compared to SHAM (p<0.05). HOMA-IR induced via ovariectomy significantly decreased by74.7% in Ovx+Exe compared to Sedentary; whereas, it significantly increased by 193.7% in OVX2 compared to SHAM2 (p<0/05). Also, HOMA-IR decreased in Ovx+Exe compared to SHAM2, but it was n ́t significant. Conclusion: 8 week aerobic-resistance training successfully decreased visceral fat and insulin resistance via increasing omentin-1. So, it seems that 8-week aerobic-resistance training with 70-85% Vo2max is suitable for controlling body weight gain, decreasing visceral fat and insulin resistance and increasing omentin-1 in menopause period.
