Sharam Gholamrezaeii; Bahman Mirzaei; Hamid Arazi; Farhad Rahmani-nia
Volume 5, Issue 2 , February 2016, , Pages 133-149
Abstract
Aim: The present study was carried out to determine the effect of garlic supplementation on some inflammatory indices following exhaustive aerobic exercise in sedentary female. Method: Nineteen volunteer sedentary young females (age 23.15±2.65 years, BMI 22.93±1.25 kg.m2,VO2max 30.36±4.5 ...
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Aim: The present study was carried out to determine the effect of garlic supplementation on some inflammatory indices following exhaustive aerobic exercise in sedentary female. Method: Nineteen volunteer sedentary young females (age 23.15±2.65 years, BMI 22.93±1.25 kg.m2,VO2max 30.36±4.5 persent and bruce time 7.82±1.03) were assigned to a randomized and double-blind into two equal garlic (n=10) and placebo (n=9) groups. After 14 consecutive days supplementation (500 mg garlic or lactose every 12 hours a day), all subjects were participated in incremental aerobic exercise protocol (Bruce test). Changes in inflammatory and enzymatic markers were determined in four phases (before supplementation phase, before exercise, immediately and 24 hours after the aerobic exercise). Data were analyzed by repeated measure and independent T test at P≤0.05. Results: The results showed that one session of exhaustive aerobic exercise significantly increased some of the inflammatory and oxidative stress markers, in both groups (P≤0.05). Also, garlic supplement can decrease Hs-crp, Lymphocyte, Neutrophil, AST and ALT levels immediately after exercise protocol (P≤0.05). But other markers (total WBC, IL-6, LDH, CPK) were not changed significant. Conclusion: The results of this study showed that the garlic supplementation leads to decrease some of inflammatory and enzymatic indices of oxidative stress. Therefore, based on the present results, garlic supplementation can reduce the oxidative stress markers ranges following the exhaustive aerobic exercise.
Ahmad Abdi; Nasrin Ramezani; Hasan Haji
Volume 5, Issue 1 , June 2015, , Pages 59-68
Abstract
Aim: Oxidative stress is an affective factor in insulin resistant, diabetes and other problems increasing blood glucose that seen in type 1 and 2 diabetes is an effective factor in producing oxidative stress. The aim of this study was to evaluate the effect of resistance training and Coriandrum sativum ...
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Aim: Oxidative stress is an affective factor in insulin resistant, diabetes and other problems increasing blood glucose that seen in type 1 and 2 diabetes is an effective factor in producing oxidative stress. The aim of this study was to evaluate the effect of resistance training and Coriandrum sativum on oxidative stress factors in diabetic male rats. Method: The present experimental study was conducted on 40 adult male rats. After induction of diabetes, the rats were randomly divided into four equal groups (1: resistance training, 2: resistance training-Coriandrum sativum extract, 3: Coriandrum sativum extract, and 4: control). Diabetic condition was induced by using 55 mg af streptozotosin per one kg body weight. Then they performed 6 weeks of resistance training (five days a week for 6 weeks and with intensity of 30-100% rats weight) and drank oral Coriandrum sativum extract (150 mg/kg daily). After 6 weeks serum levels of total antioxidant capacity (TAC), superoxide dismutase (SOD) and catalase (CAT) were measured. Results: The results showed that resistance training alonge with Coriandrum sativum extract increased serum levels of TAC, SOD and CAT (p<0.05) significantly. Also, TAC level was increased in resistance and Coriandrum sativum extract groups (p<0.05). Conclusion: It seems that six weeks at resistance training combined with Coriandrum sativum extract may have a positive effect on body anti-oxidant system and treatment of diabetes.
