Document Type : Research Paper I Open Access I Released under (CC BY-NC) license
Authors
1 Msc in Exercise Physiology
2 Associate Professor, University of Tehran
3 Professor, University of Tehran
Abstract
Aim: The purpose of this study is to compare the effect of high intensity interval training (HIIT) and aerobic training (AT) on PGC-1α gene expression in the soleus muscle of healthy adult male rats.
Method: 18 Wistar male rats were divided into three groups: HIIT (n=6), AT (n=6) and the control group (n=6). After 2 weeks of adaptation, the exercise protocol started and lasted for 8 weeks. The HIIT protocol was a 6 minute warm-up (50%-60% VO2max), 3 frequencies ( 4 minutes on 90%-100% VO2max and 2 minutes on 50%-60% VO2max) and 6 minutes of cooling down on 60-50% of VO2max and AT protocol was a 6 minute warm-up ( 50%-60% VO2max), main body which lasted for 30 minutes (70%-75% VO2max) and 6 minutes of cooling down ( 50%-60% VO2max). 24 hours after the last workout session, muscle samples were extracted and the expression level of the mentioned variable was measured by RT-PCR.
Results: The results marked that PGC-1α gene expression was increased significantly (P≤0.05) after 8 weeks of HIIT and AT, and there were no remarkable differences between the types of exercise.
Conclusion: Based on these findings, HIIT and AT have almost the same impact on increasing the muscle PGC-1α gene expression in rats’ soleus muscle.
Keywords
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