Document Type : Research Paper I Open Access I Released under (CC BY-NC) license


1 Associate professor, Ferdowsi University of Mashhad

2 Instructor, Department of Physical Education and Sport Sciences, Marivan Branch, Islamic Azad University

3 PhD student in Exercise Physiology

4 Instructor, Department of Physical Education and Sport Sciences, Gorgan Branch, Islamic Azad University

5 Instructor, Department of Physical Education and Sport Sciences, Payame Noor University


Aim: The purpose of this study was to examine the response of the visfatin to acute endurance exercise pre and post 8-weeks trainingin untrained obese healthy men.
Method: Twenty two subjects (age 29.06±3.83 years, weight 90.96±4.68 kg, height 171.3±4.88 cm, and BMI 30.76±1.8 kg/m2) were volunteered to participate in the current study. The subjects were divided randomly into two experimental (n=11) and control (n=11) groups. Experimental group participated in 8-week endurance training program three times per week. Exercise intensity increased from 60 percent of maximum heart rate to 65 to 70 percent after 4thweeks until  the end of training program. Acute exercise test (cycle ergometer exercise, 30 min at 60 percent of maximum heart rate) were employed before and after training period. Blood samples were collected before, immediately, and 30 min after acute exercise at before and after endurance training period to measure plasma visfatin variations.
Results: The results by two-way Anova with analysis showed before training period, visfation levels changes were not sigificant after acute exercise , immediately and 30 min aftery in  both groups.
Conclusion: These data indicate that endurance training is associated with decrease in resting plasma visfatin and body fat in obese men. Moreover, one bout of endurance training can decrease the plasma visfatin in response to acute exercise.