Document Type : Research Paper I Open Access I Released under (CC BY-NC) license
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Abstract
Aim: Interleukin 13 is a cytokine that can be generated during type 2 immune responses and increased as an inflammatory factor in attention deficit hyperactivity disorder.
The aim of this study was to investigate the effect of 6 weeks high intensity interval training on interleukin 13 levels and insulin resistance in adolescents with attention deficit hyperactivity disorder (ADHD).
Method: In this quasi-experimental research, thirty adolescent boys (mean age: 12.7±5.3 years; body mass index: 25.7±3.2) and thirty adolescent girls (mean age: 12.6±5.4 years; body mass index: 26.3±2.8) with ADHD were randomly allocated to high intensity interval training and control groups. The high intensity interval group performed three HIIT sessions per week for 6 weeks. Each session consisted of four to six repeats of maximal sprint running within a 20-m area with 20-30s recoveries. At the beginning and end of the sixth week interleukin 13 levels and insulin resistance index were assessed. Data were analyzed with ANCOVA with SPSS16 at the significant levels of p<0.05.
Results: Data analysis showed that high intensity interval training decreased significantly anthropometric indices, interleukin 13 and insulin resistance index in experimental group.
Conclusion: The present study revealed that high intensity interval training as an effective method has a positive impact on weight loss, increased level of serum interleukin 13 and insulin resistance index in adolescents with ADHD.
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