Document Type : Research Paper I Open Access I Released under (CC BY-NC) license
Authors
1 PhD student of exercise physiology, Tabriz Azad University, Tabriz, Iran,
2 Associate Professor of Exercise Physiology, Faculty of Human Sciences, Tabriz Azad University, Tabriz, Iran
3 Assistant Professor of Veterinary Medicine, Tabriz Azad University, Faculty of Veterinary Medicine, Tabriz, Iran
Abstract
Purpose: The present study aimed to determine 2 months of combined exercise training on the expression of PERK and IRE1α genes in Wistar male rats' Vastus lateralis muscle.
Method: The present study was conducted in a three-group experimental design with control group. 35 male Wistar rats were randomly assigned to four groups of control, endurance, strength, and endurance-strength and In addition to the control group, the next three groups participated in exercise exercises for two months. 48 hours after the last training session, and expression of PERK and IRE1α genes of Wistar male rats evaluated by Real Time-PCR. Data were analyzed using one way ANOVA at a significant level of P <0.05.
Results: The results of this study showed that, after two months of endurance training, expression of IRE1α and PERK genes were significantly increased compared to the control group. Resistance training group did not have any effect on IRE1α gene expression but increased expression of PERK gene compared to control group. Also, the combined exercise group did not differ in the expression of IRE1α gene compared to the control group but increased the expression of PERK gene compared to the control group.
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