Document Type : Research Paper I Open Access I Released under (CC BY-NC) license

Authors

1 Professor of Exercise Physiology, Faculty of Sports Sciences, University of Birjand,

2 Department of Sport Sciences, Faculty of Sport Sciences, University of Birjand, Birjand, Iran

3 Department of Sport Sciences, Faculty of Sport Sciences, Birjand, Iran

Abstract

Background and Aim: The aim of this study was to investigate the effect of 6 weeks of CXWORX training along with nettle supplement consumption on lipid profile, C-reactive protein and some body composition indicators of overweight and obese women. Methods: The current research was semi-experimental with a pre-test and post-test design. For this purpose, 48 overweight and obese women with an age range of 20-40 years and a body mass index (BMI) between 25-34 kg/m2 were purposefully selected and divided into 4 groups: exercise + nettle, exercise + placebo, nettle and Placebo was divided. All measurements were done one stage before the start of the course and another stage after the course was finished. After collecting the data, the data were analyzed with SPSS software, and Shapiro-Wilk, T-correlated tests and one-way analysis of variance were used at a significance level of p<0.05. Results: The results showed that after 6 weeks of intervention, the levels of triglycerides (p=0.105), total cholesterol (p=0.995), high-density lipoprotein (p=0.112), and low-density lipoprotein (0.506) p = ) and C-reactive protein (p = 0.965) did not show any significant difference between the research groups. But there was a significant difference in body weight (p=0.004), body mass index (p=0.010) and ratio of waist circumference to hip circumference (p=0.000) among research groups. Conclusion: 6 weeks of CXWORX training along with nettle supplementation can reduce body weight, body mass index and waist to hip ratio.

Keywords

Main Subjects

  1. Pereira AA, Santos GF, Baganha RJ, de Oliveira JJ, Harley A, Oliveira RV.(2018). Effects of aerobic training versus resistance training on body composition and systemic biochemical parameters of overweight or obese adults. Journal of Exercise Physiology. 21(2): 227-40.
  2. Pardo F, Villalobos-Labra R, Sobrevia B, Toledo F, Sobrevia L.(2018). Extracellular vesicles in obesity and diabetes mellitus. Mol Aspects Med; 60:81–91.
  3. Haeusler RA.(2020). On the Front Line: Obesity and NAFLD. Cell Metab;31.
  4. Adair T, Lopez AD.(2020). The role of overweight and obesity in adverse cardiovascular disease mortality trends: an analysis of multiple cause of death data from Australia and the USA. BMC Med;18(1):1–11.
  5. Avgerinos KI, Spyrou N, Mantzoros CS, Dalamaga M.(2019). Obesity and cancer risk: Emerging biological mechanisms and perspectives. Metabolism; 92:121–35.
  6. Vekic J, Zeljkovic A, Stefanovic A, Jelic-Ivanovic Z, Spasojevic-Kalimanovska V.(2019). Obesity and dyslipidemia. Metabolism; 92:71–81.
  7. Keikha F, Ansari H, khosravi M, Seraji M.(2021). The Effect of Educational Intervention on Health Literacy and Nutritional Performance of Female High School Students in Zahedan. Journal of Health Literacy. 6(1):41-50.
  8. Aghdasi Z, Tehrani H, Esmaiely H, Ghavami M, VahedianShahroodi M.(2021). Application of social cognitive theory on maternal nutritional behavior for weight of children 6 to 12 months with Failure to thrive (FTT). Iranian Journal of Health Education and Health Promotion. 9(2):145-58.:42.
  9. Yaghoobpour Yekani O, Azarbayjani MA, Peeri M, Farzanegi P.(2018). [Effect of type of training on markers of hepatocyte apoptosis in rats fed with high fat diet (Persian)]. Yafte. 19(5): 106-6.
  10. Polanka BM, Vrany EA, Patel J, Stewart JC.(2017). Depressive Disorder Subtypes as Predictors of Incident Obesity in US Adults: Moderation by Race/Ethnicity. Am J Epidemiol. 185(9):734-742.
  11. Kloc M., Uosef A., Kubiak J.Z., Ghobrial R.M.(2021). Role of Macrophages and RhoA Pathway in Atherosclerosis. International Journal of Molecular Sciences, 22(1): 216.
  12. Kazeminia M, Salari N, Mohammadi M.(2020). Prevalence of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus in Iran: A Systematic Review and MetaAnalysis. Journal of Diabetes Research. Sep 25.
  13. George C, Evans J, Micklesfield LK, Olsson T, Goedecke JH.(2018). The association between high-sensitivity C-reactive protein and metabolic risk factors in black and white South African. women: a cross-sectional study. BMC Obes. 7: 5-14.
  14. Cuevas AG, Kawachi I, Ortiz K, Pena M, Reitzel LR, McNeill LH.(2020). Greater social cohesion is associated with lower body mass index among African American adults. Preventive Medicine Reports.
  15. Reddy P, Vishwakarma R, Satyanarayana K.(2020). Study of lipid profile in overweight and obese children. IJHCR. 3(5):55-62.
  16. Ellulu MS, Patimah I, Khaza'ai H, Rahmat A, Abed Y.(2017). Obesity and inflammation: the linking mechanism and the complications. Archives of Medical Science; 13(4):851-863.
  17. Jeong H, Baek S-Y, Kim SW, Park E-J, Lee J, Kim H, et al.(2019). C reactive protein level as a marker for dyslipidaemia, diabetes and metabolic syndrome: results from the Korea National Health and Nutrition Examination Survey. BMJ open. 9(8): e029861.
  18. Felger JC, Haroon E, Patel TA, Goldsmith DR, Wommack EC, Woolwine BJ, et al.(2018). What does plasma CRP tell us about peripheral and central inflammation in depression? Molecular psychiatry. 1-11.
  19. Kregiel, D., Pawlikowska, E. and Antolak, H. (2018). Urtica spp.: Ordinary plants with extraordinary properties. Molecules, 23(7), 1-21.
  20. Loshali A, Joshi B, Sundriyal A. (2019).Pharmacognostical and Pharmacological Review of Urtica dioica L. Research & Reviews A Journal of Pharmacognosy. 6(2):23-9.
  21. Khanaki K, Abedinzade M, Hamidi M.(2019). The Effects of Urtica dioica and Lamium album Extracts on the Expression Level of Cyclooxygenase-2 and Caspase-3 in the Liver and Kidney of Streptozotocin-Induced Diabetic Rats. Pharmaceutical Sciences. 25(1):37-43.
  22. Ziaei R, Foshati S, Hadi A, Kermani MAH, Ghavami A, Clark CC, et al.(2020). The effect of nettle (Urtica dioica) supplementation on the glycemic control of patients with type 2 diabetes mellitus: A systematic review and meta‐ analysis. Phytotherapy Research. 34(2):282-94.
  23. Jafari Z, Samani SA, Jafari M.(2020). Insights into the bioactive compounds and physico-chemical characteristics of the extracted oils from Urtica dioica and Urtica pilulifera. SN Applied Sciences. 2(3):1-8.
  24. Shahraki MR, Mirshekari H, Shahraki AR, Shafighi E.(2013). Effect of urtica dioica decoction on Serum glucose and lipid profile in stereptozotocin induced diabetic male rats. Zahedan Journal of Research in Medical Sciences; 15(11): 15-
  25. Madadi Jaberi, M., Vahidian-Rezazadeh, M., Mogharnasi, M., & Karaji Bani, M. (2016). The effect of 8 weeks of aerobic training and consumption of hydro-alcoholic extract of nettle on apelin and hs-crp plasma levels of overweight and obese women. Armaghane Danesh, 21(9), 846-859. [Persian].
  26. Bauman A, Rutter H, Baur L.(2019). Too little, too slowly: international perspectives on childhood obesity. Public Health Res Pract. 29(1).
  27. Lee J, Stone AJ.(2020). Combined aerobic and resistance training for cardiorespiratory fitness, muscle strength, and walking capacity after stroke: a systematic review and meta-analysis. Journal of Stroke and Cerebrovascular Diseases. 29 (1): 104498.
  28. Horak M, Zlamal F, Iliev R, Kucera J, Cacek J, Svobodova L, et al.(2018). Exercise-induced circulating microRNA changes in athletes in various training scenarios. 13(1):1-8.
  29. Christle JW, Knapp S, Geisberger M, Cervenka M, Moneghetti K, Myers J, et al.(2020). Interval endurance and resistance training as part of a community-based secondary prevention program for patients with diabetes mellitus and coronary artery disease. Journal of Cardiopulmonary Rehabilitation and Prevention 40(1):17- 23.
  30. Lippi G, Henry BM, Sanchis-Gomar F.(2020). Physical inactivity and cardiovascular disease at the time of coronavirus disease 2019 (COVID-19). Eur J Prev Cardiol; 27(9): 906-8.
  31. Woods JA, Hutchinson NT, Powers SK, Roberts WO, Gomez-Cabrera MC, Radak Z, et al.(2020). The COVID-19 pandemic and physical activity. Sports Medicine and Health Science. 2(2):55-64.
  32. N.G. Lutchenko, N.I. Perevoznikova, V.G. Ivanov,(2017). Journal: Problems of modern pedagogical education, 55-5, 171- 177.

33.Yorks, D.M., Frothingham, C.A. and Schuenke, M.D.(2017). Effects of Group Fitness Classes on Stress and Quality of Life of Medical Students. The Journal of the American Osteopathic Association, 117[11], p.e17.

  1. Gottschall JS, Mills J, Hastings B. (2011). Optimal Core Training for Functional Gains and Peak Performance: CXWORX. Pennstate.
  2. Joseph MS, Tincopa MA, Walden P, Jackson E, Conte ML, Rubenfire M.(2019).The Impact Of Structured Exercise Programs On Metabolic Syndrome And Its Components: A Systematic Review. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy12:2395.
  3. Beqa Ahmeti G, Idrizovic K, Elezi A, Zenic N, Ostojic L.(2020). Endurance Training vs. Circuit Resistance Training: Effects on Lipid Profile and Anthropometric/Body Composition Status in Healthy Young Adult Women. International Journal of Environmental Research and Public Health. 17(4):1222.
  4. Handschin C, Spiegelman BM.(2008). The role of exercise and PGC-1α in inflammation and chronic disease. Nature. 454(7203): 463-469.
  5. Eklund D, Häkkinen A, Laukkanen Ja, Balandzic M, Nyman K, Häkkinen K.(2016). Fitness, Body Composition And Blood Lipids Following 3 Concurrent Strength And Endurance Training Modes. Applied Physiology, Nutrition, And Metabolism. 41(7):767-74.
  6. Porto JM, Spilla SB, Cangussu-Oliveira LM, Freire Junior RC, Nakaishi APM, de Abreu DCC.(2020). Effect of aging on trunk muscle function and its influence on falls among older adults. J Aging Phys Act; 1-8. [Epub ahead of print].
  7. 40. Weissman RS, Bauer S, Thomas JJ.(2020). Access to evidence‐ based care for eating disorders during the COVID‐19 crisis. Int J Eat Disord; 53(5): 639-46.
  8. Hassani, A., Ebrahimi, M., & Ramezanpoor, M. R.(2011). Survey on the effect of eight weeks of regular aerobic exercise with consumption of nettle extract on blood glucose and insulin resistance index among women with Type II Diabetes. Journal of Knowledge & Health, 10(4), 57-64. [Persian].
  9. Namazi N, Tarighat Esfanjani A.(2011). Effect alcoholic extract of nettle on insulin sensitivity and some inflammatory markers in patients with diabetes2. Scientific Journal of Hamadan University of Medical Sciences and Health Services; 4(18): 10-13.
  10. Azarbayjani MA, Abedi B. (2012). Comparison of Aerobic, Resistance and Concurrent Exercise on Lipid Profiles and Adiponectin in Sedentary Men. Knowldeg Health J. 7 (1): 32- 38.
  11. Qorbani Ganjeh Z, Gholami M, Nikbakht H. (2019). Effect of resistance training with different intensities on adiponectin and lipid profiles in overweight women. The Scientific Journal of Rehabilitation Medicine. 8(4): 47-55. [Persian].
  12. Sepehrirad M, Valipour Dehnou V, Fathi M. (2018). Effects of hict on serum lipids and glucose levels in elderly women. Iran Journal of Nursing. 31 (115): 20-28. [Persian].

 

  1. Racil G, Coquart JB, Elmontassar W, Haddad M, Goebel R, Chaouachi A, Amri M, Chamari K. (2016). Greater effects of high-compared with moderate-intensity interval training on cardiometabolic variables, blood leptin concentration and ratings of perceived exertion in obese adolescent females. Biology of sport. 33(2): 145.
  2. Benson AC, Torode ME, Singh MF. (2008). The effect of high-intensity progressive resistance training on adiposity in children: a randomized controlled trial. International journal of obesity. 32(6): 1016-27.
  3. Ouerghi N, Fradj MKB, Bezrati I, Khammassi M, Feki M, Kaabachi N, et al. (2017). Effects of high-intensity interval training on body composition, aerobic and anaerobic performance and plasma lipids in overweight/obese and normal-weight young men. Biology of sport. 34: 385–392.
  4. Onakpoya IJ, Heneghan C. (2015). Effect of the novel functional fibre, polyglycoplex (PGX), on body weight and metabolic parameters: a systematic review of randomized clinical trials. J Clin Nutr; 34:1109-14.
  5. Ghadery B, Ghazalian F, Hosseini SA, Abed Natanzy H, Shamsoddini A. (2020). Effect of high-intensity interval training with eryngium campestre on lipid profile and glycemic indices in high- fat dietinduced obese rats. Hormozgan Med J. 24 (2): e98982.
  6. Foster C, Shilton T, Westerman L, Varney J, Bull F. (2018). World Health Organisation to develop global action plan to promote physical activity: Time for action. Br J Sports Med; 52(8): 484-5.
  7. Snorrason I, Beard C, Christensen K, Bjornsson AS, Björgvinsson T. (2019). Body dysmorphic disorder and major depressive episode have comorbidity-independent associations with suicidality in an acute psychiatric setting. J Affect Disord. 259:266-270.
  8. Strasser B, Siebert U, Schobersberger W. Resistance training in the treatment of the metabolic syndrome: a systematic review and meta-analysis of the effect of resistance training on metabolic clustering in patients with abnormal glucose m (19): 397-415.
  9. Cuevas AG, Kawachi I, Ortiz K, Pena M, Reitzel LR, McNeill LH. (2020). Greater social cohesion is associated with lower body mass index among African American adults. Preventive Medicine Reports.
  10. Olson TP, Dengel DR, Leon AS, Schmitz KH. (2007). Changes in inflammatory biomarkers following one-year of moderate resistance training in overweight women. Int J Obesity. 31 (6): 996-1003.
  11. 56. Plaisance EP, Taylor JK, Alhassan S, Abebe A, Mestek ML, Grandjean PW. (2007). Cardiovascular fitness and vascular inflammatory markers after acute aerobic exercise. Int J Sport Nutr Exerc Metab. 17(2):152- 62.
  12. 57. Hammett CJ, Prapavessis H, Baldi JC, Varo N, Schoenbeck U, Ameratunga R, et al. (2006). Effects of exercise training on 5 inflammatory markers associated with cardiovascular risk. Am Heart J. 151(2): 367.e7- 367.e16.
  13. 58. Colbert LH, Visser M, Simonsick EM, Tracy RP, Newman AB, Kritchevsky SB, et al. (2004). Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study. J Am Geriatr Soc. 52(7):1098-104.