Aim: Physical exercise acts as a mechanical stressor that can elicit biochemical alterations. Thus, muscular effort is able to modify blood concentrations of some cellular enzymes. The purpose of this study was to investigate the effects of one progressive session exercise in day during one week on some enzymes muscle damage such as creatine phospho Kinase (CPK), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) in active girls.
Method: thirteen girls students of physical education with mean (Vo2max 41.07±5.11 ml/kg/min) was selected and randomly divided to experimental group (one session of exercise in day, on a treadmill at a rate of 6-8 km/h for 3 min with 1min of active rest between sets until exhaustion, n=7) and control group (n=6). Venous blood samples were obtained for analysis before of exercise (base line) and 1, 4, 7 days during of exercise period, as well as after the 24 hours last progressive session exercise. Data of study were analyzed by repeated measure ANOVA and independent t test. The significant level was set at P≤0.05.
Results: The result of this study indicated that AST, LDH and CPK were significantly higher after 1, 4 and 7 days exercise than the resting level (P≤0.05), but after 24 h of end period, this Diff were significantly lower than at the exercise day (P≤0.05).
Conclusion: These results suggested that acute exposure to progressive session exercise without adequate recovery can lead to reduced performance and a more dramatically increase in muscle damage enzymes.
Key words: Progressive exercise, muscle damage, LDH, CPK, AST.