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Abstract

Abstract
Aim: Nesfatin-1 is a novel adipokine secreted by adipose tissue and interfere in regulation of blood Glucose, improvement of insulin sensitivity, appetite regulation, energy homeostasis and metabolic function. Given the importance of resistance exercise in prevention and treatment of overweight and obesity, the purpose of this study was to determine the effect of eight weeks resistance training on plasma levels of nesfatin-1 in overweight women.
Method: Thirty-eight overweight women (age 34.84±5.70 y, BMI 28.82±3.65 kg/ m2, body fat percent 36.34±3.39 % and WHR 0.85±0.04 (means ± SD)) were randomly divided into 2 groups. Resistance exercise training (50 min/day, 60-70% 1-RM, 4 days/week). Fasting blood samples were collected to assess changes in plasma Nesfatin, insulin and glucose levels in before and after 2 months of the training program. Independent t-test and Pearson correlation coefficient were used for further analysis (P

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