Document Type : Research Paper I Open Access I Released under (CC BY-NC) license

Authors

1 Associate Professor

2 Assistant Professor

Abstract

Aim: Myostatin and follistatin proteins are important proteins in the regulation of muscle tissue. Therefore, the aim of this study was to investigate the effect of 8 weeks of HIIT training on the serum levels of myostatin and follistatin in inactive young women.
Method: The present study was conducted in a semi-experimental manner with two experimental and control groups on 30 inactive young women in the age range of 30-35 years. The experimental group performed HIIT exercises for 8 weeks, and three sessions per week for 60 minutes with an intensity of 65-75% of the maximum heart rate, and during this period, the control group had no physical activity. Blood samples were taken after 48 hours before and after exercise intervention in order to measure myostatin and follistatin variables. Data were analyzed using covariance test.
Result: The results of this research showed that the serum level of myostatin decreased significantly in the experimental group compared to the control group after 8 weeks of HIIT exercises (P<0.001), while the serum level of follistatin increased significantly in the experimental group compared to the control group in the post-test. You have shown (P<0.001).
Conclusion: HIIT exercises can decrease the expression of myostatin and increase the expression of follistatin in human samples and can lead to muscle hypertrophy and can be used as an exercise intervention in the rehabilitation program of inactive women. be placed.
Keywords: HIIT; Myostatin, follistatin, young women

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