Document Type : Research Paper I Open Access I Released under (CC BY-NC) license


1 university of guilan

2 Guilan university of medical sciences


Aim: the purpose of This study aimed to investigate the impact of 8 weeks of using three exercise regimens on glucose profiles and fat percentage in women with MS.
Methods: This experimental study included 40 females diagnosed with MS (mean age: 34.30 ± 3.50). The participants were randomly assigned to four groups (N=10): aerobic training (AT), resistance training (RT), combined aerobic and resistance training (AT+RT), and control. The RT involved a series of movements using weighted vests (5-10% of body weight) for three days per week. The AT sessions were conducted for two days per week, lasting 10-30 minutes (40-60% of maximum heart rate). The AT+RT group performed exercises five days per week (two days of AT and three days of RT). Data analysis employed two-way ANOVA with repeated measures and Bonferroni's post hoc test. Statistical analysis was conducted using SPSS version 26 software, with a significance level of 0.05.
Results: The results revealed no significant differences between groups. However, within-group analyses demonstrated a significant decrease in insulin, cortisol, HbA1C, and HOMA-IR levels compared to baseline in the intervention groups.
Conclusions: These findings suggest that exercise interventions have the potential to positively influence metabolic parameters in individuals with MS. Further research is needed to explore optimal exercise protocols and long-term effects in this population.
Key words: Multiple sclerosis, body composition, sugar profile


Main Subjects