Document Type : Research Paper I Open Access I Released under (CC BY-NC) license


1 Department of Sport Sciences, Faculty of Social Sciences, Imam Khomeini International University, Qazvin, Iran

2 Imamkhomeini International University

3 Department of Internal Medicine, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran


Introduction: Non-alcoholic fatty liver disease is a chronic liver condition that can be caused by a lack of physical activity and a decrease in cardiopulmonary function. Improving lifestyle and increasing physical activity can be effective in ameliorating the condition. Chromium supplementation has been found to be effective in improving the health of individuals with obesity, diabetes, and insulin resistance.
Objective: The aim of this study was to investigate the impact of a six-week exercise snacking program and chromium supplementation on patients with non-alcoholic fatty liver disease.
Methods: In this study, 30 participants with fatty liver grade 1, 2, or 3 were randomly divided into four groups: exercise and chromium (N=8), chromium (N=8), exercise (N=7), and control (N=7). Measurements were taken for ALT and AST levels, triglycerides, body weight, age, waist circumference, and sonogram diagnosis.
Findings: The results showed a significant decrease in fatty liver grade in both the exercise and chromium group (P=0.02) and the exercise group (P=0.01). Additionally, there was a significant decrease in ALT levels in the exercise and chromium group (P=0.001) after six weeks. These findings suggest that exercise snacking, either alone or with chromium supplementation, can be effective in ameliorating non-alcoholic fatty liver disease.
Conclusion: This study provides support for the use of exercise snacking, either alone or with chromium supplementation, as an effective treatment for non-alcoholic fatty liver disease. These findings suggest that physical activity, in the form of exercise snacking, can be a suitable intervention for patients with NAFLD.


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