Document Type : Research Paper I Open Access I Released under (CC BY-NC) license
Authors
1 Associate Professor, Department of Exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran
2 Assistant Professor of Exercise Physiology, Department of Physical Education and Sport Sciences, Islamic Azad University, Marivan Branch, Marivan, Iran
3 Master of Science, Department of Exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran
Abstract
Introduction: Intense exercise increases the expression of cell damage/death factors. Therefore, the aim of the present study was to investigate the effect of gender on the levels of apoptotic proteins following intense resistance exercise.
Methodology: In this study, 18 men and women aged between 18 and 30 were randomly selected and divided into two groups of 9 participants each. The resistance exercise consisted of 6 stations: barbell front arm, barbell chest press, underarm with machine, leg press with machine, back with machine, and shoulder with barbell. Each station was performed for 4 repetitions at an intensity of 80% of the one-repetition maximum (1RM). The interval between sets was 60 to 90 seconds, and the interval between stations was 2 minutes. Blood samples were collected before and immediately after the activity.
Results: The results of the repeated-measures analysis of variance (ANOVA) showed that the effect of gender on the level of the apoptotic protein Bax (F(1,17)=1.66, P=0.214) and the anti-apoptotic protein Bcl-2 (F(1,17)=0.32, P=0.57) was not significant. However, the effect of time on the level of the Bax apoptotic protein was significant (F(1,17)=30.28, P<0.0001). Post-hoc tests using Bonferroni's correction indicated a significant increase in Bax protein levels after the activity compared to the pre-test levels in both groups (P<0.05).
Conclusions: In this research, intense resistance activity led to a similar increase in the apoptotic protein Bax in young men and women. However, it had no effect on the anti-apoptotic protein Bcl-2, and gender did not influence the levels of either protein.
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