Document Type : Research Paper I Open Access I Released under (CC BY-NC) license
Authors
1 Samira Ahadi Affiliation: PHD student of Exercise Physiology, Department of Physical Education, Tabriz branch, Islamic Azad University, Tabriz, Iran,
2 : Assistant Prof., Department of Exercise Physiology, Tabriz branch, Islamic Azad University, Tabriz, Iran
3 Associate Professor, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran
Abstract
The aerobic interval training program was conducted for eight weeks, three sessions per week, with a progressive increase in duration (20 to 60 minutes) and intensity (60–75% of heart rate reserve, calculated using the Karvonen formula). During weeks 1 and 2, participants exercised for 20 minutes at 60% heart rate reserve, while in weeks 7 and 8, training duration increased to 60 minutes at 75% heart rate reserve. Each training session included a 10-minute warm-up (brisk walking and stretching exercises) and a 5-minute cool-down (light jogging and stretching). Plasma Aβ42/Aβ40 ratio and metabolic control indices were measured before and after the intervention using enzyme-linked immunosorbent assay (ELISA). Fasting blood glucose (FBG), HDL, and insulin levels were measured enzymatically, and insulin resistance was calculated using a standard formula. Paired and independent t-tests were used for statistical analysis at a significance level of α = 0.05. Results: Paired t-test results showed a significant difference in HOMA-IR between pretest and posttest measurements in both the control (p = 0.006) and aerobic interval training groups (p = 0.002). Next, the results of an independent t-test on the amount of change (Δ) showed that the HOMA-IR value decreased in the aerobic interval training group compared to the control group. However, for other variables, including fasting blood glucose, HDL, and the Aβ42/Aβ40 ratio, significant changes were observed only in the aerobic interval training group (FBG: p = 0.001; HDL: p = 0.02; Aβ42/Aβ40: p = 0.002).
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