Motahareh Hajati Modaraei; Mohammad Reza Kordi; Aabbas Ali Gaeini
Volume 4, Issue 1 , May 2014, , Pages 39-48
Abstract
Aim: The purpose of this study is to compare the effect of high intensity interval training (HIIT) and aerobic training (AT) on PGC-1α gene expression in the soleus muscle of healthy adult male rats. Method: 18 Wistar male rats were divided into three groups: HIIT (n=6), AT (n=6) and the control ...
Read More
Aim: The purpose of this study is to compare the effect of high intensity interval training (HIIT) and aerobic training (AT) on PGC-1α gene expression in the soleus muscle of healthy adult male rats. Method: 18 Wistar male rats were divided into three groups: HIIT (n=6), AT (n=6) and the control group (n=6). After 2 weeks of adaptation, the exercise protocol started and lasted for 8 weeks. The HIIT protocol was a 6 minute warm-up (50%-60% VO2max), 3 frequencies ( 4 minutes on 90%-100% VO2max and 2 minutes on 50%-60% VO2max) and 6 minutes of cooling down on 60-50% of VO2max and AT protocol was a 6 minute warm-up ( 50%-60% VO2max), main body which lasted for 30 minutes (70%-75% VO2max) and 6 minutes of cooling down ( 50%-60% VO2max). 24 hours after the last workout session, muscle samples were extracted and the expression level of the mentioned variable was measured by RT-PCR. Results: The results marked that PGC-1α gene expression was increased significantly (P≤0.05) after 8 weeks of HIIT and AT, and there were no remarkable differences between the types of exercise. Conclusion: Based on these findings, HIIT and AT have almost the same impact on increasing the muscle PGC-1α gene expression in rats’ soleus muscle.
