Metabolism and Exercise

Introduction: Many diseases cause skeletal muscle microvascular rarefaction (MR) and the quantitative determination of the effect size (ES) of exercise training on skeletal muscle capillary ... Read More Introduction: Many diseases cause skeletal muscle microvascular rarefaction (MR) and the quantitative determination of the effect size (ES) of exercise training on skeletal muscle capillary to fiber ratio (C/F) can be useful in refining exercise prescriptions for susceptible population. The aim of the present study was to determine the average ES of exercise training on skeletal muscle C/f in patients disposed to MR. Methodology: A search for English articles was conducted in Web of Science, Scopus, and PubMed databases without limiting the year of publication until February 2023. Weighted mean difference (WMD) with 95% confidence intervals was calculated using random effect model. Correlation between variables was investigated using fixed effects model meta-regression. Results: A summary ES achieved as WMD=0.21 (95% CI: 0.17 to 0.26) from the results of 308 subjects, included in 22 exercise training interventions (p=0.014, I2=44.16). No correlations were observed in between the changes in C/F and the age of subjects included in each intervention based on action of the moment’s meta-regression model (r=-0.00, p=0.92, z=0.099). Among the exercise duration categories, interventions less than 8 weeks (n=3) had the least ES on C/F (WMD=0.18), while a WMD of 0.22 were determined for both of interventions with 8 weeks (n=7) and more than 8 weeks duration (n=12) categories (z=9.68, p=0.001). Moreover, interventions in HIIT and intensive aerobic exercise training category had greater ES (WMD=0.23) compared to MICT and aerobic exercise training (WMD= 020) interventions (z=9.73, p=0.001). Conclusions: Taken together, these findings propose that the beneficial effects of exercise training on skeletal muscle microvascular density can ensue in susceptible patients regardless of their age, and higher intensity as well as longer duration exercise programs should be emphasized. however, more investigations remain to be done because of the lack of evidence in this area.

Effect of High-Intensity Interval Training and Curcumin Supplementation on Cardiac Tissue HSP60 and HSP20 Levels and Gene Expression levels of miR-21 and miR-30 in Rats Exposed to Arsenic

Aghil Mahdavi; Roghayeh Pouzesh Jadidi; Karim Azali Alamdari

Volume 12, Issue 1 , March 2022, , Pages 35-58

https://doi.org/10.22124/jme.2023.21057.223

Abstract

Introduction: The aim of this study was to evaluate the effects of high-intensity interval training (HIIT) and curcumin supplementation on cardiac heat shock proteins level and gene ... Read More

Effect of aerobic training before and after a meal on serum acylated ghrelin level, daily energy intake and single exercise energy expenditure in overweight men

Karim Azali Alamdari; Y yavari; R Hosseinzadeh; A Rahbar Ghazi

Volume 9, Issue 1 , August 2020, , Pages 15-25

https://doi.org/10.22124/jme.2020.4353

Abstract

Aim: In this study the effects of a single training session of overweight men before and after a meal on serum acetylated ghrelin levels, daily energy intake and the exercise energy ... Read More

Effect of aerobic training on chemerin, CRP and metabolic risk factors in middle age obese men

K Azali Alamadari; S Nasiri; Z Mohammadpour

Volume 8, Issue 1 , June 2018, , Pages 15-27

https://doi.org/10.22124/jme.2018.3561

Abstract

Aim: The aim of this study was to investigate the effects of aerobic training on serum Chemerin levels, inflammatory and cardio-metabolic risk factors in factors in midlife males complicated ... Read More

Synchronized effects of aerobic training and magnesium supplementation on cardiometabolic risk factors and A1c in Type 2 diabetic females

K Azali Alamdari K; M Bashiri; R Shokrzadeh Agha Alilou

Volume 7, Issue 1 , August 2017, , Pages 39-54

https://doi.org/10.22124/jme.2017.3373

Abstract

Aim: Nowadays the effect of physical exercise on diabetes control improvement is evident and the both insulin release and function depends on magnesium (Mg) and Mg even improves insulin ... Read More Aim: Nowadays the effect of physical exercise on diabetes control improvement is evident and the both insulin release and function depends on magnesium (Mg) and Mg even improves insulin sensitivity. However; diabetes causes hypomagnesiumemia which in turn worsens glycemic control in a viscous cycle. Likewise; little is known about the synchronized effects of exercise training along with Mg supplementation on diabetes control. Therefore; the aim of this study was to investigate the synergistic effects from eight weeks of aerobic training and magnesium supplementation on metabolic control, blood insulin and glycosylated Hb (A1C) and Mg levels in female patients with type II diabetes. Method: This study was done based on an experimental method using a pretest-posttest design. Thirty volunteer midlife type II diabetic females were randomized into training-Mg, training-placebo and control groups. The subjects consumed magnesium oxide or amylose containing pills (250 mg) once daily in a double blind order for eight weeks. The training groups also experienced eight weeks of moderate intensity aerobic training (3 sessions/week running for 60 min in each session at 40 to 60% of THR). Fasting blood samples were taken at two occasions between 8 to 9 am; baseline and after the intervention and the data were analyzed using paired samples t test and one way ANOVA at 95% significance level. Results: 30% of the subjects had hypomagnesiumemia at baseline. Blood Mg was just elevated in the training-Mg group throughout the intervention (P<0.05). However; blood glucose, insulin, A1C, TG, waist circumference and blood pressure were all declined in both the training groups (P<0.05). Additionally, there were greater depressions in blood glucose and insulin levels of the training-Mg group rather than training placebo group (P<0.05). Conclusion: Aerobic training and synchronized Mg supplementation could provide a better diabetes control along with other therapeutic proceedings.

Effect of aerobic training on retinol binding protein-4 and insulin resistance in women with metabolic syndrome

Karim Azali Alamdari; Farhad Gholami

Volume 5, Issue 2 , February 2016, , Pages 109-119

Abstract

Aim: Retinol binding protein-4 (RBP-4) as an adipokine secreted from adipose tissue, plays an important role in insulin resistance and metabolic disorders. Despite the benefits of aerobic ... Read More Aim: Retinol binding protein-4 (RBP-4) as an adipokine secreted from adipose tissue, plays an important role in insulin resistance and metabolic disorders. Despite the benefits of aerobic training on metabolic disorders, the effect of aerobic training on RBP-4 and its relation with metabolic factors in patients with metabolic syndrome is unclear. Therefore, the aim of this study was to investigate the effect of eight weeks aerobic training on serum RBP-4 levels and insulin resistance in women with metabolic syndrome. Methods: In a semi-experimental study, 24 women with metabolic syndrome (age: 52.79±4.91 yrs, BMI: 32.77±2.37 Kg/m2 and VO2peak: 40±2.55 L/min) were randomly assigned into two groups including exercise (n=12) and control (n=12) groups. Aerobic exercise program was performed for 8 weeks, 3 sessions per week with an intensity of 50-60% of peak oxygen consumption for 20-40 minutes. Prior to the experimental period and 48h after last training session, body composition measurements were performed and blood samples were taken to be measured for serum levels of RBP-4, lipid profile, glucose and insulin. Insulin resistance index was also assessed. The data were analyzed using statistical tests of Paired and Independent t-test and Pearson's correlation test at significance level of PResults: The results showed that aerobic training significantly decreased serum RBP-4, glucose, insulin resistance index, body weight, body fat percentage, body mass index (BMI), waist circumference and metabolic syndrome Z score (P<0.05). Moreover, high density lipoprotein HDL - C levels significantly increased following eight weeks aerobic training (P<0.05). Pearson's correlation test revealed that changes in RBP-4 levels was significantly correlated with changes in body fat percentage, triglycerides, insulin and insulin resistance index (P<0.05). Conclusion: Overall, the results of this study indicated that aerobic training can reduce the RBP-4 levels and improve insulin resistance and some metabolic risk factors in women with metabolic syndrome. Insulin resistance improvement is likely to be resulted from decreased RBP-4 levels following aerobic training.

Effects of submaximal aerobic training and following detraining on serum BDNF level and memory function in midlife healthy untrained males

Arsalan Damirchi; Karim Azali Alamdari; Parvin Babaei

Volume 2, Issue 2 , July 2012, , Pages 135-147

Abstract

Abstract Aim: Brain derived neurotrophic factor (BDNF) is an important factor affecting cognitive function which has recently interested a bulk trend of effort in the health context. ... Read More

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Author = Azali Alamadari, K

Effect of Exercise Training on Capillary to Myofiber Ratio in Patients at Higher Risk of Microvascular Rarefaction: A Meta-Analysis Study

Abstract

Effect of High-Intensity Interval Training and Curcumin Supplementation on Cardiac Tissue HSP60 and HSP20 Levels and Gene Expression levels of miR-21 and miR-30 in Rats Exposed to Arsenic

Abstract

Effect of aerobic training before and after a meal on serum acylated ghrelin level, daily energy intake and single exercise energy expenditure in overweight men

Abstract

Effect of aerobic training on chemerin, CRP and metabolic risk factors in middle age obese men

Abstract

Synchronized effects of aerobic training and magnesium supplementation on cardiometabolic risk factors and A1c in Type 2 diabetic females

Abstract

Effect of aerobic training on retinol binding protein-4 and insulin resistance in women with metabolic syndrome

Abstract

Effects of submaximal aerobic training and following detraining on serum BDNF level and memory function in midlife healthy untrained males

Abstract