Sh Mirdar; E Asadi; A Arzani; Gh Hamidiyan
Abstract
Aim: Estrogens binding to estrogen receptors in the cytoplasm, causing an increase in the synthesis of DNA, RNA and others proteins in the target tissue. Endurance exercises may affect the expression of estrogen receptors in overectomized rats. Therefore, the aim of present study was to investigate the ...
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Aim: Estrogens binding to estrogen receptors in the cytoplasm, causing an increase in the synthesis of DNA, RNA and others proteins in the target tissue. Endurance exercises may affect the expression of estrogen receptors in overectomized rats. Therefore, the aim of present study was to investigate the effect of six weeks swimming training on expression of estrogen receptors in the uterus and fallopian tubes in overectomized rats.
Method: thirty female Wistar rats with an average weight of 90-110g, were randomly assigned into three groups, consist of control, sham and swimming training. swimming time at first was 30 minutes for each session that daily increased 5 minutes until reached 60 minutes per day in second week and remained 60 minutes to end of training period (6 week). expression of estrogen receptors in fallopian tubes and uterus tissues were measured by immunohistochemistry assay. data analyzed by ANOVA and Tukey test at α≥0.005
Results: The mean levels of estrogen receptors expression in uterus were not significantly different between training with control group. But differences were significant between training and control groups with sham group (P<0.01). expression of estrogen receptors increased %78.43 in sham group and decreased %2.3 in training group in comparison to control group.
Conclusion: the results of present study indicated that six weeks' swimming training haven’t any effect on expression of estrogen receptors in overectomized rat uterus tissue.
َAkram Arzani; Sadmehr Mirdar; Mehdi Hedayati
Volume 4, Issue 2 , December 2015, , Pages 151-158
Abstract
Objective: The aquaporin5 (AQP5) is an integral membrane protein that plays an important role in maintaining water homeostasis in the lung. The purpose of this study was to evaluate the effect of interval training on AQP5 levels in the lung of Male Wistar rats during puberty. Methodology: 30 three-week ...
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Objective: The aquaporin5 (AQP5) is an integral membrane protein that plays an important role in maintaining water homeostasis in the lung. The purpose of this study was to evaluate the effect of interval training on AQP5 levels in the lung of Male Wistar rats during puberty. Methodology: 30 three-week male Wistar rats with average weight of 68±9 g were randomly divided into three groups included; the base, control and training groups. The training group ran on treadmill for 6 weeks (6 per week, 30 minutes each session at a speed of 15 to70 meters per minute). AQP5 levels were measured by ELISA methods. Analyzed is done with two-way ANOVA and LSD test at PResults: Results showed significant differences between AQP5 levels of control, base and training groups (P<0.05). While, there were no significant differencesbetween AQP5 levels of control and base groups . Furthermore, six-weeks interval training increased AQP5 levels of lung tissue in exercise group compared to the control group by 229.03 and 284.9 percent. Conclusion: It seems that an Increased interval training can improve the of epithelial cell performance and protect the AQP5 level changes during the puberty, and improve lung liquid homeostasis.
Shadmehr Mirdar; Encieh Rahimi; Hadi Baghban
Volume 3, Issue 2 , July 2014, , Pages 167-179
Abstract
Abstract
Aim: The growth factor myostatin and IGF-1 play a major role in response to muscular contractions and in the regulation and stimulation of muscles metabolism. This research aim is to study the effects of ginseng on the myostatin and IGF-1.
Method: Therefore, 16 athletes were selected. The ...
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Abstract
Aim: The growth factor myostatin and IGF-1 play a major role in response to muscular contractions and in the regulation and stimulation of muscles metabolism. This research aim is to study the effects of ginseng on the myostatin and IGF-1.
Method: Therefore, 16 athletes were selected. The research was constructed as a two-way blinded semi- experimental, pre-post test with a control group. Participants were divided into two groups: Ginseng and placebo. Blood sampling was done before and after one month supplementation and after a simulated competition.Data analysis was done by repeated measures analysis of variance, LSD post hoc and independent T-test.
Results: Results showed that level of myostatin and IGF-1 were influenced by using ginseng and simulated competition (P
Shadmehr Mirdar; Masoomeh Nobahar
Volume 2, Issue 1 , April 2012
Abstract
Abstract
Aim: Physical exercise acts as a mechanical stressor that can elicit biochemical alterations. Thus, muscular effort is able to modify blood concentrations of some cellular enzymes. The purpose of this study was to investigate the effects of one progressive session exercise in day during one ...
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Abstract
Aim: Physical exercise acts as a mechanical stressor that can elicit biochemical alterations. Thus, muscular effort is able to modify blood concentrations of some cellular enzymes. The purpose of this study was to investigate the effects of one progressive session exercise in day during one week on some enzymes muscle damage such as creatine phospho Kinase (CPK), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) in active girls.
Method: thirteen girls students of physical education with mean (Vo2max 41.07±5.11 ml/kg/min) was selected and randomly divided to experimental group (one session of exercise in day, on a treadmill at a rate of 6-8 km/h for 3 min with 1min of active rest between sets until exhaustion, n=7) and control group (n=6). Venous blood samples were obtained for analysis before of exercise (base line) and 1, 4, 7 days during of exercise period, as well as after the 24 hours last progressive session exercise. Data of study were analyzed by repeated measure ANOVA and independent t test. The significant level was set at P≤0.05.
Results: The result of this study indicated that AST, LDH and CPK were significantly higher after 1, 4 and 7 days exercise than the resting level (P≤0.05), but after 24 h of end period, this Diff were significantly lower than at the exercise day (P≤0.05).
Conclusion: These results suggested that acute exposure to progressive session exercise without adequate recovery can lead to reduced performance and a more dramatically increase in muscle damage enzymes.
Key words: Progressive exercise, muscle damage, LDH, CPK, AST.
Shadmehr Mirdar; Maedehsadat Raisi; Masoomeh Nobahar
Volume 1, Issue 1 , April 2011, , Pages 11-23
Abstract
AbstractAim: The objective of this research was to investigate the effect of two peaks exercise training program during one week on some hepatic stress indexes (AST, ALT) in active girls.
Method: Twelve physical education girl students with ranged between 16-18 years old and mean maximal oxygen consumption ...
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AbstractAim: The objective of this research was to investigate the effect of two peaks exercise training program during one week on some hepatic stress indexes (AST, ALT) in active girls.
Method: Twelve physical education girl students with ranged between 16-18 years old and mean maximal oxygen consumption 35.2±3.4 ml/kg/min, was selected and divided randomly into an experimental (n=7) and control (n=5) groups. The subjects in the experimental group performed two peaks exercise training program during one week with 70%, 80%, and 90% VO2max intensities in the first three days and repeated in late three days. The control group did not perform any physical activity while the research was underway. Venous blood samples were obtained for analysis before the exercise and the 24 hours after one, 3, 6 days exercise sessions. Data were analyzed by using ANOVA with repeated measure test and independent t-test at significant levels p
