Exercise Physiology
amir khosravi; Vahid Valipour Dehnou; Rima Shayan Nasab; sakine Jafarian
Abstract
Aim: One of the complications of menopause that plays an important role in reducing the quality of life is the reduction of body fat-free mass. The aim of this study was to determine the effect of a period of whole body vibration course on myostatin and follistatin Serum in Postmenopausal Women. Methods: ...
Read More
Aim: One of the complications of menopause that plays an important role in reducing the quality of life is the reduction of body fat-free mass. The aim of this study was to determine the effect of a period of whole body vibration course on myostatin and follistatin Serum in Postmenopausal Women. Methods: In this semi experimental study, 20 postmenopausal women with hypothyroidism were selected and divided into two groups of 10: control (C) and whole body vibration training (V). Group V performed these exercises for 12 weeks and three times a week, with a frequency of 30 to 50 Hz, applying on upper and lower limb training. At the beginning and end of the study, blood serum myostatin and follistatin levels were measured using the ELISA method, , body fat percentage, body mass index, and body weight. Due to the normality of data distribution, independent t and covariance statistical methods were used for analysis at a significance level of 0.05. Results: 12 weeks of whole body vibration training in group V significantly increased the serum levels of follistatin (P=0.001), and decreased myostatine (P=0.018) compared to the control group. There was also a significant decrease in body fat percentage (P=0.041), body mass index (P=0.044) and weight (P=0.047).Conclusions: It seems that whole body vibration training increases serum levels of follistatin and decreases myostatin in postmenopausal women, and these positive changes may play an important role in improving lean mass of postmenopausal women.
Karim Azali Alamdari; Farhad Gholami
Volume 5, Issue 2 , February 2016, , Pages 109-119
Abstract
Aim: Retinol binding protein-4 (RBP-4) as an adipokine secreted from adipose tissue, plays an important role in insulin resistance and metabolic disorders. Despite the benefits of aerobic training on metabolic disorders, the effect of aerobic training on RBP-4 and its relation with metabolic factors ...
Read More
Aim: Retinol binding protein-4 (RBP-4) as an adipokine secreted from adipose tissue, plays an important role in insulin resistance and metabolic disorders. Despite the benefits of aerobic training on metabolic disorders, the effect of aerobic training on RBP-4 and its relation with metabolic factors in patients with metabolic syndrome is unclear. Therefore, the aim of this study was to investigate the effect of eight weeks aerobic training on serum RBP-4 levels and insulin resistance in women with metabolic syndrome. Methods: In a semi-experimental study, 24 women with metabolic syndrome (age: 52.79±4.91 yrs, BMI: 32.77±2.37 Kg/m2 and VO2peak: 40±2.55 L/min) were randomly assigned into two groups including exercise (n=12) and control (n=12) groups. Aerobic exercise program was performed for 8 weeks, 3 sessions per week with an intensity of 50-60% of peak oxygen consumption for 20-40 minutes. Prior to the experimental period and 48h after last training session, body composition measurements were performed and blood samples were taken to be measured for serum levels of RBP-4, lipid profile, glucose and insulin. Insulin resistance index was also assessed. The data were analyzed using statistical tests of Paired and Independent t-test and Pearson's correlation test at significance level of PResults: The results showed that aerobic training significantly decreased serum RBP-4, glucose, insulin resistance index, body weight, body fat percentage, body mass index (BMI), waist circumference and metabolic syndrome Z score (P<0.05). Moreover, high density lipoprotein HDL - C levels significantly increased following eight weeks aerobic training (P<0.05). Pearson's correlation test revealed that changes in RBP-4 levels was significantly correlated with changes in body fat percentage, triglycerides, insulin and insulin resistance index (P<0.05). Conclusion: Overall, the results of this study indicated that aerobic training can reduce the RBP-4 levels and improve insulin resistance and some metabolic risk factors in women with metabolic syndrome. Insulin resistance improvement is likely to be resulted from decreased RBP-4 levels following aerobic training.
