Payam Saidei; Hamid Mohebbi; Farhad Rahmaninia; Fahimeh Mohammad ghasemi
Volume 4, Issue 2 , December 2015, , Pages 89-108
Abstract
Objective: The aim of the present study was to investigate the effect of 10-week negative energy balance (NEB) methods on adipocyte size and adiponectin levels in different abdominal fat depots as well as glucose and lipid variables and insulin resistance in high-fat-diet obese male wistar rats. Methodology: ...
Read More
Objective: The aim of the present study was to investigate the effect of 10-week negative energy balance (NEB) methods on adipocyte size and adiponectin levels in different abdominal fat depots as well as glucose and lipid variables and insulin resistance in high-fat-diet obese male wistar rats. Methodology: Study sample were consisted of sixty-four Wistar male rats (average weight; 194.5±12.6g). Blood samples were collected at 1st, 18th and 28th weeks after an overnight fasting. After first sampling, remaining 56 rats were randomly divided into control (n=16) and high-fat-diet (n=40) groups. After 18 weeks High-fat-diet group randomly divided into high-fat-diet (HFD) and negative energy balance consisted of calorie restriction, exercise training and combination (exercise training with calorie restriction) subgroups. Negative energy balance subgroups underwent an aerobic training (running) with intensity of 70 to 75% of VO2max, %25 calorie restriction and interval of both methods for 10 weeks. Adiponectin Levels and adipocyte size in retroperitoneal and mesenteric fat depots, insulin and glucose levels and lipid profile were measured. HOMA-IR was also calculated. Results: The results of this study indicated that in comparison to high-fat-diet, negative energy balance methods despite consumption of high fat diet, decreased adipocyte size in retroperitoneal and mesenteric fat depots (P<0.05) and insulin resistance index improved in line with decrease of serum concentrations of insulin, glucose and triglyceride in obese male rats (P<0.05). However although lipid profile improved, only triglyceride concentration significantly decreased (P<0.05). From negative energy balance subgroups only combination showed significant increase in adiponectin levels of studied depots compared to high-fat-diet (P>0.05). Conclusion: This study indicated that negative energy balance methods can actually decrease adipocyte size of retroperitoneal and mesenteric fat depots even with simultaneous consumption of high-fat-diet which is largely congruent with improvement in lipid and metabolic profile Results also indicate a superiority of aerobic training in improving the lipid profile compare to other NEB methods.
Mohammadreza Hamedinia; Amirhosin Haghighi; Mohammadali Sardar; Javad Pourjahad
Volume 2, Issue 2 , July 2012, , Pages 125-133
Abstract
Abstract
Aim: The aim of this study was to determine the effect of exercise training in water on serum adiponectin and insulin resistance in obese children and adolescents.
Method: For this purpose 60 obese subjects (children 10-12 years and adolescents 14-16 years) were randomly assigned into one ...
Read More
Abstract
Aim: The aim of this study was to determine the effect of exercise training in water on serum adiponectin and insulin resistance in obese children and adolescents.
Method: For this purpose 60 obese subjects (children 10-12 years and adolescents 14-16 years) were randomly assigned into one of four groups: exercise training in water for both children and adolescents, and control groups (children and adolescents). Experimental groups underwent exercise training for 8 weeks; 3 sessions per week and 60 minutes per session, with an intensity of 60-85% of maximum heart rate. Blood samples, anthropometric and body composition measures were taken before and after training program.
Results: Data analysis using ANOVA showed that exercise training in water caused a significant decrease in body fat percent, and increase in VO2max in the children and adolescents. Exercise training in water had no effect on serum adiponectin and insulin resistance.
Conclusion: In summary, since 8 weeks exercise training in water did not cause weight loss, it probably had no effect on adiponectin and insulin resistance.
Key words: Exercise training in water, Adiponectin, Obesity, Adolescents, children, Insulin resistance
