Exercise Physiology
Maryam Kafi; khadijeh irandoust
Abstract
Introduction: The aim of this study was to evaluate the importance of aerobic exercise and quercetin supplementation on the progression of colon cancer in rats and changes in the effects of IGF1 and myostatin on muscle tissue and the shape of fluctuations in atrophy and muscle wasting. Methods: The subjects ...
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Introduction: The aim of this study was to evaluate the importance of aerobic exercise and quercetin supplementation on the progression of colon cancer in rats and changes in the effects of IGF1 and myostatin on muscle tissue and the shape of fluctuations in atrophy and muscle wasting. Methods: The subjects of this study included 25 male Wistar rats (weight: 250± 30 g, age: 12 weeks) which were homogenized by weight and randomly divided into 5 groups (5 heads in each group) of healthy controls. Cancer control group, cancer group + quercetin supplement, cancer group + aerobic exercise, cancer group + quercetin supplement + aerobic exercise was evaluated. Measurements of IGF1 and myostatin in muscle tissue of rats were performed according to the standard and ELISA method. SPSS software was used for data analysis. Results: The results showed that 8 weeks of aerobic training in muscle tissue of mice with colon cancer had a significant effect on the mean values of myostatin (p = 0.005) and IGF1 (p = 0.019). 8 weeks of quercetin supplementation in muscle tissue of mice with colon cancer had a significant effect on mean myostatin and mean values IGF (P <0.05) in the control and experimental groups (8 weeks of quercetin supplementation) had no significant effect on mean myostatin and IGF1. (P>0/05) Conclusion: In general, the findings showed that aerobic exercise and quercetin supplementation improve IGF1 and reduce myostatin in muscle tissue of mice with colon cancer.
Exercise Physiology
mina shakhi; Aboalhamid habibi; aliakbar alizadeh
Abstract
Introduction and purpose: The purpose of this research is to investigate the effect of exercise (resistance-aerobic) on the levels of IGFBP3, IGF1, and BMI in obese wome .Materials and methods: For this purpose, 24 inactive obese women aged 25 to 37 years with a BMI of 30 to 35 kg/m2 were randomly divided ...
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Introduction and purpose: The purpose of this research is to investigate the effect of exercise (resistance-aerobic) on the levels of IGFBP3, IGF1, and BMI in obese wome .Materials and methods: For this purpose, 24 inactive obese women aged 25 to 37 years with a BMI of 30 to 35 kg/m2 were randomly divided into two groups of 12 people, training and control. The selected exercise included resistance training with weights and a special bodybuilding machine with an intensity of 67 to 80% of the maximum strength and aerobic exercise with a stationary bike and an intensity of 60 to 85% of the maximum heart rate, for 8 weeks and 3 days a week. Body composition measurements were taken 24 hours before and 24 hours after exercise. For statistical analysis in the findings section, one-way analysis of covariance test was used to examine inter-group changes. Findings: The results of this study showed that after eight weeks of resistance and aerobic training, a significant decrease in the BMI of subjects in the training group was observed compared to the control group (P<0.001). Also, the results of analysis of covariance showed that after eight weeks of selected training (resistance-aerobic) the two indexes of IGFBP3 and IGF1 in the training group decreased significantly compared to the control group (P<0.001 and P<0.006, respectively). Conclusion: According to the results of this research, both resistance and aerobic training methods can be used to reduce weight, BMI, IGFBP3 and IGF1.
Shadmehr Mirdar; Encieh Rahimi; Hadi Baghban
Volume 3, Issue 2 , July 2014, , Pages 167-179
Abstract
Abstract
Aim: The growth factor myostatin and IGF-1 play a major role in response to muscular contractions and in the regulation and stimulation of muscles metabolism. This research aim is to study the effects of ginseng on the myostatin and IGF-1.
Method: Therefore, 16 athletes were selected. The ...
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Abstract
Aim: The growth factor myostatin and IGF-1 play a major role in response to muscular contractions and in the regulation and stimulation of muscles metabolism. This research aim is to study the effects of ginseng on the myostatin and IGF-1.
Method: Therefore, 16 athletes were selected. The research was constructed as a two-way blinded semi- experimental, pre-post test with a control group. Participants were divided into two groups: Ginseng and placebo. Blood sampling was done before and after one month supplementation and after a simulated competition.Data analysis was done by repeated measures analysis of variance, LSD post hoc and independent T-test.
Results: Results showed that level of myostatin and IGF-1 were influenced by using ginseng and simulated competition (P
