B Ghanivand; B Nakhostinroohi
Abstract
Aim: Curcumin is as an anti-inflammatory and antioxidant agent. The aim of this study was to evaluate the effect of curcumin supplementation on muscle damage indices following intensive eccentric exercise.
Method: Ten healthy, nonsmoking, active young men participated in this cross over study. Participants ...
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Aim: Curcumin is as an anti-inflammatory and antioxidant agent. The aim of this study was to evaluate the effect of curcumin supplementation on muscle damage indices following intensive eccentric exercise.
Method: Ten healthy, nonsmoking, active young men participated in this cross over study. Participants were randomized in a double-blind placebo-controlled fashion in two placebo (P), and curcumin (C) groups. After first blood sampling, subjects did a session of intensive squat exercise. Immediately after exercise, a second blood sampling was collected. Afterward, subjects took 150 mg curcumin or placebo, and sampling was performed 24, 48, and 72h after exercise blood sampling was done again. After a two weeks recovery period and with the change of supplements the test were repeated. Creatine Kinase (CK), and bilirubin were measured as muscle damage markers. Visual Analogue Scale (VAS), Range of Motion of the knee (ROM), and tissue swelling were measured at all time series.
Results: CK significantly decreased in C group 24h after exercise compared with the P group (P<0.05). Bilirubin significantly decreased in C group 72h after exercise compared with the P group (P<0.05). VAS was increased in both in both group exercise, but showed significant decrease in C group compared with P group 48 and 72h after exercise (P<0.05).
Conclusion: It seems 150mg curcumin supplementation after a session of intensive eccentric exercise ameliorate pain and muscle damage through its analgesic, anti-inflammatory, and anti-oxidative properties..
Bahman Mirzaei; Farhad Rahmani nia; Amir Rashidlami; Mehdi Ghahremani Moghaddam
Volume 3, Issue 2 , July 2014, , Pages 129-139
Abstract
Abstract
Aim: Aging in human is associated with a loss in neuromuscular function and performance. This is related, in part, to increased oxidative stress and decreased antioxidants status. Uric acid and bilirubin considered as two main antioxidant in blood and have a significant relationship with Total ...
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Abstract
Aim: Aging in human is associated with a loss in neuromuscular function and performance. This is related, in part, to increased oxidative stress and decreased antioxidants status. Uric acid and bilirubin considered as two main antioxidant in blood and have a significant relationship with Total Anti Oxiidait Capaciy. The aim of present study was to examin the effects of resistance exercise on total antioxidant capacity, bilirubin and uric acid in non-athlete and elderly wrestlers.
Method: 8 elderly wrestlers (age 59.75 ± 1.98, Height 172.25 ± 7.08 cm, Weight 76 ± 14.6 kg) and 7 untrained (age 61.42 ± 1.9, Height 173.14 ± 4.09 cm, Weight 79.71 ± 8.15 kg) elderly people volunteered as subject for the study. Subjects completed resistance exercise protocol including: bench press, leg extension, lat-machine pull down, leg curl, cable triceps curl and cable biceps curl with 60-70% of 1RM and with 8-12 repetitions. Blood samples were colected at pre, post and 24 hours after resistance exercise.
Results: Resistance exercise did not caused any significancant differences in indices but the baseline amount of total bilirubin and TAC was higher in athlete group, but not significantly.
Conclusion: The results of this study showed a single bout of resistance exercise had not significant effect on antioxidant status in athlete and non-athlete elderly men.
Key words: Antioxidant, Aging, Uric acid, Bilirubin, Wrestling.
