Masoud Shakki; Fatemeh Hosseini; Saeed Ghorbani; reza rezai shirazi; H parsian
Abstract
Aim: The purpose of the study was to investigate the effect of 8 weeks of aerobic interval exercise with silymarin supplementation on antioxidant, liver damage and atherogenic indicators in male Wistar rats fed a high-fat diet.Methods: This experimental study with laboratory method was performed on 35 ...
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Aim: The purpose of the study was to investigate the effect of 8 weeks of aerobic interval exercise with silymarin supplementation on antioxidant, liver damage and atherogenic indicators in male Wistar rats fed a high-fat diet.Methods: This experimental study with laboratory method was performed on 35 male Wistar rats with a body weight of 160.45±7.08g and 3-weeks-of-age were randomly divided into 5 groups consisted of ordinary diet control (ODC), fatty diet control (FDC), fatty diet with supplement (FDS), fatty diet with exercise (FDE), fatty diet with supplement and exercise (FDSE). The exercises included the running on treadmill for 8 weeks, five times/week and 30 minutes in an exercise session. Silymarin supplementation with dose of 140 mg/kg/day of body, weight was received for two weeks. Liver tissue and samples were obtained after 48 hours of the last diet and data analyzed. Results: Significant decrease in FDSE and FDE groups compared with FDC group in ALT, AST, and ALP, MDA, TC and TG variables were observed. Whereas, there were significantly increased in FDSE group compared with FDC in SOD and HDL-C variables. Also, LDL-C and AIP in FDSE group compared with FDC had shown a significant decrease (p> .05).Conclusion: The applying of aerobic interval exercise alone or with silymarin supplementation reduced the risk to NAFLD such as enzymes involved and atherogenic index in male Wistar rats fed a high-fat diet; therefore, it could probably improve the disease through increase the antioxidant capacity and reduce blood lipid profiles.
Bahman Mirzaei; Farhad Rahmani nia; Amir Rashidlami; Mehdi Ghahremani Moghaddam
Volume 3, Issue 2 , July 2014, , Pages 129-139
Abstract
Abstract
Aim: Aging in human is associated with a loss in neuromuscular function and performance. This is related, in part, to increased oxidative stress and decreased antioxidants status. Uric acid and bilirubin considered as two main antioxidant in blood and have a significant relationship with Total ...
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Abstract
Aim: Aging in human is associated with a loss in neuromuscular function and performance. This is related, in part, to increased oxidative stress and decreased antioxidants status. Uric acid and bilirubin considered as two main antioxidant in blood and have a significant relationship with Total Anti Oxiidait Capaciy. The aim of present study was to examin the effects of resistance exercise on total antioxidant capacity, bilirubin and uric acid in non-athlete and elderly wrestlers.
Method: 8 elderly wrestlers (age 59.75 ± 1.98, Height 172.25 ± 7.08 cm, Weight 76 ± 14.6 kg) and 7 untrained (age 61.42 ± 1.9, Height 173.14 ± 4.09 cm, Weight 79.71 ± 8.15 kg) elderly people volunteered as subject for the study. Subjects completed resistance exercise protocol including: bench press, leg extension, lat-machine pull down, leg curl, cable triceps curl and cable biceps curl with 60-70% of 1RM and with 8-12 repetitions. Blood samples were colected at pre, post and 24 hours after resistance exercise.
Results: Resistance exercise did not caused any significancant differences in indices but the baseline amount of total bilirubin and TAC was higher in athlete group, but not significantly.
Conclusion: The results of this study showed a single bout of resistance exercise had not significant effect on antioxidant status in athlete and non-athlete elderly men.
Key words: Antioxidant, Aging, Uric acid, Bilirubin, Wrestling.
