Document Type : Research Paper I Open Access I Released under (CC BY-NC) license
Authors
1 PhD candidate of exercise physiology, University of Tabriz, Tabriz, Iran
2 Associate professor of exercise physiology, University of Tabriz, Tabriz, Iran
3 Assistant professor of exercise physiology, University of Tabriz, Tabriz, Iran
Abstract
Backgrounds: The aim of the present study is to determine the effect of eight weeks of high intensity interval training, resistance and combined training on hormonal factors and microRNAs related to obesity and sports adaptations in obese adolescent boys.
Methods: 36 healthy, sedentary boys (age range: 13-15 years; BMI: 28-31 Kg/m2; Fat Percent: 32-36%) were divided into four groups of intense, resistance and combined intermittent exercise and control (no activity) based on aerobic capacity and fat percentage. Each HIIT session consisted of 6-8 repetitions of 30-60 second sprints at 80-85% (three minutes rest between repetitions). Resistance training included movements of the main muscles of the upper body, trunk and lower body. Combined training consisted of a combination of resistance training and HIIT. The expression of miRNA-133a, miRNA-1 and miRNA-143 in obese and overweight adolescent boys was measured before and after the exercise training protocols.
Results: The results of the present study showed that after completing all three training protocols, the expression levels of miRNA-133a, miRNA-1 and miRNA-143 decreased significantly compared to the pre-test stage. Also, only in the combined group, a significant difference was observed between the expression changes of miRNA-133a and miRNA-1 with the resistance training group, but the expression levels of miRNA-133a, miRNA-1 and miRNA-143 did not differ between the combined group and the HIIT group.
Conclusion: Based on the results of the present study, it seems that using a combination of HIIT and resistance training is a suitable method to increase sports adaptations at the cellular level.
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