Exercise Physiology
Solmaz Babaei; Morteza Fattahpour Marani
Abstract
Aim: Myostatin and follistatin proteins are important proteins in the regulation of muscle tissue. Therefore, the aim of this study was to investigate the effect of 8 weeks of HIIT training on the serum levels of myostatin and follistatin in inactive young women.Method: The present study was conducted ...
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Aim: Myostatin and follistatin proteins are important proteins in the regulation of muscle tissue. Therefore, the aim of this study was to investigate the effect of 8 weeks of HIIT training on the serum levels of myostatin and follistatin in inactive young women.Method: The present study was conducted in a semi-experimental manner with two experimental and control groups on 30 inactive young women in the age range of 30-35 years. The experimental group performed HIIT exercises for 8 weeks, and three sessions per week for 60 minutes with an intensity of 65-75% of the maximum heart rate, and during this period, the control group had no physical activity. Blood samples were taken after 48 hours before and after exercise intervention in order to measure myostatin and follistatin variables. Data were analyzed using covariance test.Result: The results of this research showed that the serum level of myostatin decreased significantly in the experimental group compared to the control group after 8 weeks of HIIT exercises (P<0.001), while the serum level of follistatin increased significantly in the experimental group compared to the control group in the post-test. You have shown (P<0.001).Conclusion: HIIT exercises can decrease the expression of myostatin and increase the expression of follistatin in human samples and can lead to muscle hypertrophy and can be used as an exercise intervention in the rehabilitation program of inactive women. be placed.Keywords: HIIT; Myostatin, follistatin, young women
Exercise Physiology
Morteza Fattahpour Marani; Solmaz Babaei
Abstract
Aim: physical activity can play a supportive role in breast cancer improvement by regulating and modulating cytokines. Interleukin 10 is an anti-inflammatory cytokine that plays an important role in preventing the growth and metastasis of breast cancer, and interleukin 4 is an inflammatory cytokine that ...
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Aim: physical activity can play a supportive role in breast cancer improvement by regulating and modulating cytokines. Interleukin 10 is an anti-inflammatory cytokine that plays an important role in preventing the growth and metastasis of breast cancer, and interleukin 4 is an inflammatory cytokine that causes the growth and development of cancer cells. The present study was conducted with the aim of investigating the effect of 12 weeks of Pilates exercises on the serum levels of interleukin 4 and interleukin 10 in women with breast cancer. Method: The present study was conducted in a semi-experimental manner with two experimental and control groups on 30 women with breast cancer. The experimental group was given Pilates exercises for 12 weeks and 3 sessions each week for 60 minutes, while the control group did not participate in any physical activity. Blood samples were taken 48 hours before and after exercise intervention to measure interleukin 4 and 10 variables. Results: Based on the results of the correlated t test, the serum level of interleukin 10 in the experimental group increased significantly compared to the control group (P=0.001), and the amount of interleukin 4 in the experimental group showed a significant decrease compared to the control group(P=0.001).Conclusion: Performing Pilates exercises with the benefit of anti-inflammatory cytokines and reducing inflammatory cytokines improves the health status of women with breast cancer. Therefore, doing exercises can help patients as a therapeutic factor. Keywords: interleukin 10, interleukin 4, Pilates exercises, breast cancer
