نوع مقاله : مقاله پژوهشی Released under (CC BY-NC) license I Open Access I
نویسندگان
1 دانشجوی دکتری فیزیولوژی ورزشی گرایش قلب و عروق و تنفس، گروه تربیت بدنی و علوم ورزشی، دانشکده علوم تربیتی و روانشناسی،دانشگاه محقق
2 دانشیار گروه تربیت بدنی و علوم ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه محقق اردبیلی، اردبیل، ایران.
3 استادیار گروه تربیت بدنی و علوم ورزشی، باشگاه پژوهشگران جوان، واحد اردبیل، دانشگاه آزاد اسلامی، اردبیل، ایران.
4 دانشیار گروه زیست شناسی ، دانشکده علوم ، دانشگاه محقق اردبیلی، اردبیل، ایران.
چکیده
هدف: تغییرات نامطلوبی که در ترکیب بدن و لیپوپروتئین ها پس از یائسگی رخ می دهد ناشی از سطح استروژن است. هدف مطالعه حاضر بررسی تاثیر 12 هفته تمرین مقاومتی با باند‌های کشی بر میزان بیانmir-217 و نیم رخ لپیدی زنان سالمند چاق یائسه بود.
روش شناسی: در این کارآزمایی بالینی تصادفی شده (RCT) یک سو کور، 24 زن سالمند چاق (سن 68/3±13/64 سال، میزان چربی56/2±2/44 درصد، شاخص توده بدنی 65/3±1/32 کیلوگرم بر متر مربع) به دو گروه کنترل (10 نفر) و تمرین (14 نفر) تقیسم شدند. گروه تمرین به مدت 12 هفته و سه جلسه در هفته تمرینات مقاومتی با باند‌های کشی را برای همه‌ی گروه‌های عضلانی اصلی انجام دادند. 48 ساعت پیش و پس از 12 هفته مداخله، آزمایش دگزا و نمونه گیری از خون انجام شد.
یافتهها: نتایج مقایسه‌های بین گروهی نشان دهنده‌ی کاهش معنی‌دار در بیان mir-217 و سطوح LDL و افزایش معنادار در HDL در گروه تمرین نسبت به گروه کنترل بود (05/0 p≤)؛ در حالی که تفاوت معنادار در وزن بدن، شاخص توده بدنی، درصد چربی، کلسترول تام و CRP مشاهده نشد (05/0P≥).
نتیجه‌گیری: به نظر می رسد 12 هفته تمرین مقاومتی با کش الاستیک سبب تعدیل و کاهش بیان mir-217 سرم خون زنان سالمند چاق می شود که این تغییرات با کاهش سطوح LDL و افزایش سطوح HDL همراه بود.اگرچه نتایج شاخص توده بدنی، درصد چربی، کلسترول تام و CRP تغییرات معناداری را نشان ندادند که احتمالاً می تواند ناشی از نوع و شدت تمرینات انجام شده باشد که نیاز به بررسی های بیشتر در این زمینه دارد.
کلیدواژه‌ها
عنوان مقاله [English]
Effect of elastic band resistance training on mir-217 expression and cardiovascular risk factors in menopausal obese elderly women
نویسندگان [English]
- negar ashrafi 1
- lotfali BOLBOLI 2
- ali khazani 3
- asadalah asadi 4
1 PhD student, Department of Exercise Physiology, University of Mohaghegh Ardabili, Ardabil, Iran
2 2- . Associated Professor, Department of physical education and sport sciences, Faculty of education sciences and psychology, University of Mohaghegh Ardabili, Ardabil, Iran
3 Department of Physical Education & Sport Sciences, Young Researchers and Elite Club, Ardabil Branch, Islamic Azad University, Ardabil, Iran
4 Associated Professor, Department of biology, Faculty of science, University of Mohaghegh Ardabili, Ardabil, Iran.
چکیده [English]
Aim: Unfavorable changes occur in the body composition and lipoprotein that are related to the loss of estrogen levels after menopause. The aim of this study was to investigate the effect of 12 weeks elastic band resistance training on mir-217 expression and cardiovascular risk factors in menopausal obese elderly women.
Method: In this single blind randomized clinical trial (RCT), 49 elderly women with obesity (age 64.13 ± 3.68 years, fat percentage 45.4 ± 6.56 %, BMI 33. 1 ± 3.71 kg/m2) were divided into two groups: control (n=10) and training (n = 14). The training group performed elastic band resistance training for 12 weeks and three sessions per week for all major muscle groups. Forty eight hours before and after 12 weeks of intervention, a DEXA test was performed.
Results: The results of the intergroup comparisons indicated a significant decrease in mir-217 expression and LDL levels and a significant increase in HDL in the training group compared to the control group (P≤0.05), whereas there was no significant difference in body weight, body mass index, fat percentage, total cholesterol and CRP (P≥0.05).
Conclusion: It seems that 12 weeks elastic band resistance training have been able to modulate and reduce the serum concentration of mir-217 in obese elderly women, which was associated with a decrease in LDL levels and increase levels of HDL. Although body mass index, fat percentage, total cholesterol and CRP Significant changes were not observed, which requires further investigation in this field.
کلیدواژه‌ها [English]
- Obesity
- Resistance training
- Elderly
- mir-217
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