نوع مقاله : مقاله پژوهشی Released under (CC BY-NC) license I Open Access I
نویسندگان
1 1 کارشناسی ارشد فیزیولوژی تغذیه ورزشی، گروه فیزیولوژی ورزشی، دانشگاه بین المللی امام خمینی، قزوین - ایران
2 استاد گروه فیزیولوژی ورزشی، دانشکده علوم اجتماعی، دانشگاه بین المللی امام خمینی، قزوین - ایران
3 دانشیار گروه فیزیولوژی ورزشی، دانشکده علوم اجتماعی، دانشگاه بین المللی امام خمینی، قزوین - ایران
4 استاد گروه رفتار حرکتی، دانشکده علوم ورزشی و تندرستی دانشگاه تهران ، دانشگاه تهران، ایران.
چکیده
هدف: هدف این پژوهش بررسی تاثیر ۸ هفته تمرینات تناوبی شدید و اعمال رژیم روزهداری بر میزان پروتین MCJ کبدی در موشهای نر ویستار است.
روش پژوهش:در این مطالعه تجربی، ۲۸ موش نر ویستار بهطور تصادفی به چهار گروه تقسیم شدند: به چهار 1.گروه کنترل، 2. گروه رژیم غذایی، 3. گروه تمرینات تناوبی شدید و 4.گروه تمرینات تناوبی شدید+رژیم غذایی. برنامه تمرینی شامل 8 هفته دویدن روی تردمیل و 5 روز در هفته بود که هفته اول دو تکرار با شدت بالا، هفته دوم چهار تکرار با شدت بالا، هفته سوم شش تکرار و از هفته چهارم به بعد شامل هشت تکرار با شدت بالا بود. از این رو زمان کل تمرین به طور میانگین در هفته اول 16 دقیقه، در هفته دوم 24 دقیقه، هفته سوم 32 دقیقه و از ابتدای هفته چهارم به بعد 40 دقیقه بود.
یافتهها : نتایج آزمون آنوا نشان داد که تمرینات تناوبی شدید (HIIT) در مقایسه با گروه کنترل سالم،تاثیر معناداری بر میزان پروتئین MCJ کبدی دارد (p=0.001). ، همچنین، ترکیب تمرینات HIIT با رژیم روزهداری در مقایسه با گروه کنترل سالم، تاثیر معناداری بر کاهش سطح پروتئین MCJ کبدی نشان داد (F=31.167 p<0.001). در مقابل، رژیم فست به تنهایی تاثیر معناداری بر پروتئین MCJ نداشت p=0.186) . (F=1.879.
نتیجه: برنامههای تمرینی شامل HIIT و رژیم روزهداری میتواند در کاهش سطح پروتین MCJ در میتوکندری کبد و متابولیسم موثر باشند.
کلیدواژهها
موضوعات
عنوان مقاله [English]
The effect of 8 weeks of high-intensity interval training and daily food intake in a fasted diet on hepatic MCJ protein expression in male Wistar rats
نویسندگان [English]
- Raha Rassolnia 1
- Khadijah Irandoust 2
- Ali hemati 3
- Morteza Taheri 4
1 Department of Sport Science, Imam Khomeini International University, Qazvin, Iran;
2 Department of Sport Sciences, Faculty of Social Sciences, Imam Khomeini International University, Qazvin, Iran Imam Khomeini International University
3 Department of Sports Science, Faculty of Social Sciences, Imam Khomeini International University. Iran
4 Department of Behavioral and Cognitive Science, Faculty of Sport Sciences and Health, University of Tehran, Tehran, Iran
چکیده [English]
Research Aim: MCJ protein expression in the liver, as one of the indicators of cellular and metabolic function, is influenced by various factors, including physical exercises and diet. The aim of this study is to investigate the effect of 8 weeks of intense intermittent exercise on male Wistar rats.
Research Method:
In this experimental study, 28 male Wistar rats were randomly divided into four groups: high-intensity interval training (HIIT), HIIT combined with fast diet, FAST, and control. Data were reported using descriptive indicators as mean and standard deviation, and the Shapiro-Wilk test was used to check the normality of the data. Then, one-way ANOVA and Bonferroni post hoc tests were used to analyze the differences between groups.
Findings:
The results of the ANOVA test showed that high-intensity interval training (HIIT) had a significant effect on the level of hepatic MCJ protein (F=15.520 p=0.001). Also, combining HIIT with a fasting diet showed a significant effect on increasing the level of hepatic MCJ protein (F=31.167 p<0.001). In contrast, fasting alone had no significant effect on MCJ protein (p=0.186) (F=1.879). The findings of this study indicate that high-intensity interval training significantly increases the expression of MCJ protein in the liver of male Wistar rats, and combining this exercise with a fasting diet enhances this effect. On the other hand, fasting alone had no significant effect on the expression of this protein. Therefore, training programs including HIIT may be effective in improving liver function and increasing the expression of proteins related to metabolism.
کلیدواژهها [English]
- Fatty liver
- Intense training
- MCJ protein
- Fasting Diet
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