1-Long JM, Holtzman DM. Alzheimer disease: an update on pathobiology and treatment strategies. Cell. 2019;179(2):312-39.[ https://www.cell.com/cell/fulltext/S0092-8674(19)31007-4].
2- Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. science. 2002 Jul 19;297(5580):353-6.[
DOI: 10.1126/science.1072994].
3-Jack Jr CR, Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB, et al. NIA-AA research framework: toward a biological definition of Alzheimer's disease. Alzheimer's & Dementia. 2018;14(4):535-62.[
doi.org/10.1016/j.jalz.2018.02.018.].
4-Wang X, Wang W, Li L, Perry G, Lee H-g, Zhu X. Oxidative stress and mitochondrial dysfunction in Alzheimer's disease. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease. 2014;1842(8):1240-7.[
doi.org/10.1016/j.bbadis.2013.10.015].
6-Rojo M, Legros F, Chateau D, Lombès A. Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo. Journal of cell science. 2002;115(8):1663-74.[
https://doi.org/10.1242/jcs.115.8.1663].
7-Kandimalla R, Manczak M, Yin X, Wang R, Reddy PH. Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer’s disease. Human molecular genetics. 2018;27(1):30-40.[
doi.org/10.1093/hmg/ddaf098].
8-Luo L, Dai J-R, Guo S-S, Lu A-M, Gao X-F, Gu Y-R, et al. Lysosomal proteolysis is associated with exercise-induced improvement of mitochondrial quality control in aged hippocampus. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences. 2017;72(10):1342-51.[
https://doi.org/10.1093/gerona/glw242].
9-Bernardo T, Marques‐Aleixo I, Beleza J, Oliveira P, Ascensao A, Magalhaes J. Physical Exercise and Brain Mitochondrial Fitness: The Possible Role Against A lzheimer's Disease. Brain Pathology. 2016;26(5):648-63.[
https://doi.org/10.1111/bpa.12403].
12-Sawda C, Moussa C, Turner RS. Resveratrol for Alzheimer's disease. Annals of the New York Academy of Sciences. 2017;1403(1):142-9.[
doi.org/10.1111/nyas.13431].
13-Tönnies E, Trushina E. Oxidative stress, synaptic dysfunction, and Alzheimer’s disease. Journal of Alzheimer's Disease. 2017;57(4):1105-21.[
https://doi.org/10.3233/JAD-161088].
14-Rahman MH, Akter R, Bhattacharya T, Abdel-Daim MM, Alkahtani S, Arafah MW, et al. Resveratrol and neuroprotection: impact and its therapeutic potential in Alzheimer's disease. Frontiers in pharmacology. 2020;11:619024.[
doi.org/10.3389/fphar.2020.619024].
15-Kwon KJ, Kim H-J, Shin CY, Han S-H. Melatonin potentiates the neuroprotective properties of resveratrol against beta-amyloid-induced neurodegeneration by modulating AMP-activated protein kinase pathways. Journal of clinical neurology (Seoul, Korea). 2010;6(3):127.[
doi.org/10.3988/jcn.2010.6.3.127].
16- Kong D, Yan Y, He XY, Yang H, Liang B, Wang J, He Y, Ding Y, Yu H. Effects of resveratrol on the mechanisms of antioxidants and estrogen in Alzheimer’s disease. BioMed research international. 2019;2019(1):8983752.[
doi.org/10.1155/2019/8983752].
17- Eslimiesfahani D., Oryan S., Khosravi M., Valizadegan F.. Effect of Fennel Extract on the Improvement of Memory Disorders in Beta Amyloid Alzheimer Model of Male Wistar Rats. Journal of Ilam University of Medical Sciences. 2019;27(1 ):1-12.[
https://sid.ir/paper/381658/en]. [In Persian]
18-Seyedhosseini Tamijani SM, Beirami E, Ahmadiani A, Dargahi L. Effect of three different regimens of repeated methamphetamine on rats’ cognitive performance. Cognitive Processing. 2018;19:107-15.[ doi.org/10.1007/s10339-017-0839-0].
19-Wu C, Yang L, Li Y, Dong Y, Yang B, Tucker LD, et al. Effects of exercise training on anxious–depressive-like behavior in Alzheimer rat. Medicine and science in sports and exercise. 2020;52(7):1456.[ doi:
10.1249/MSS.0000000000002294].
21-Nakamura T, Cieplak P, Cho D-H, Godzik A, Lipton SA. S-nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegeneration. Mitochondrion. 2010;10(5):573-8.[
doi.org/10.1016/j.mito.2010.04.007].
22-Flannery PJ, Trushina E. Mitochondrial dynamics and transport in Alzheimer's disease. Molecular and Cellular Neuroscience. 2019;98:109-20.[
doi.org/10.1016/j.mcn.2019.06.009].
23-Reddy PH, McWeeney S, Park BS, Manczak M, Gutala RV, Partovi D, et al. Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease. Human molecular genetics. 2004;13(12):1225-40.[
doi.org/10.1093/hmg/ddh140].
24-Marques-Aleixo I, Santos-Alves E, Balça M, Rizo-Roca D, Moreira P, Oliveira P, et al. Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto (mito) phagy markers. Neuroscience. 2015;301:480-95.[
doi.org/10.1016/j.neuroscience.2015.06.027].
25-Tanaka T, Nishimura A, Nishiyama K, Goto T, Numaga-Tomita T, Nishida M. Mitochondrial dynamics in exercise physiology. Pflügers Archiv-European Journal of Physiology. 2020;472(2):137-53.[ DOI:
10.1007/s00424-019-02258-3].
26-Yan Z, Lira VA, Greene NP. Exercise training-induced regulation of mitochondrial quality. Exercise and sport sciences reviews. 2012;40(3):159.[
doi:10.1097/JES.0b013e3182575599].
27- Trewin AJ, Berry BJ, Wojtovich AP. Exercise and Mitochondrial Dynamics: Keeping in Shape with ROS and AMPK. Antioxidants (Basel). 2018 Jan 6;7(1):7. [
doi.org/10.3390/antiox7010007].
28-Marton O, Koltai E, Takeda M, Koch LG, Britton SL, Davies KJ, et al. Mitochondrial biogenesis-associated factors underlie the magnitude of response to aerobic endurance training in rats. Pflügers Archiv-European Journal of Physiology. 2015;467(4):779-88 .[
https://link.springer.com/article/10.1007/s00424-014-1554-7.
30-Zorzano A, Liesa M, Sebastián D, Segalés J. Regulation of mitofusin-2 expression in skeletal muscle: relationship with insulin sensitivity. Am J Physiol Endocrinol Metab. 2010;299(5):E798–E805.[
doi.org/10.1139/H09-049].
32-Palomera-Avalos V, Griñán-Ferré C, Puigoriol-Ilamola D, Camins A, Sanfeliu C, Canudas AM, et al. Resveratrol protects SAMP8 brain under metabolic stress: focus on mitochondrial function and Wnt pathway. Molecular neurobiology. 2017;54:1661-76.[ doi.org/10.1007/s12035-016-9770-0].
33-Cao Y, Sun W, Liu C, Zhou Z, Deng Z, Zhang M, et al. Resveratrol ameliorates diabetic encephalopathy through PDE4D/PKA/Drp1 signaling. Brain Research Bulletin. 2023;203:110763.[
doi.org/10.1016/j.brainresbull.2023.110763].
34- Peng K, Tao Y, Zhang J, Wang J, Ye F, Dan G, Zhao Y, Cai Y, Zhao J, Wu Q, Zou Z. Resveratrol regulates mitochondrial biogenesis and fission/fusion to attenuate rotenone‐induced neurotoxicity. Oxidative medicine and cellular longevity. 2016;2016(1):6705621.[
https://doi.org/10.1155/2016/6705621].
35-Manczak M, Mao P, Calkins MJ, Cornea A, Reddy AP, Murphy MP, et al. Mitochondria-targeted antioxidants protect against amyloid-β toxicity in Alzheimer's disease neurons. Journal of Alzheimer's Disease. 2010;20(s2):S609-S31.[
https://doi.org/10.3233/JAD-2010-100564].
37-delroz h, Abdi A, Barari A, Farzanegi P. Protective Effect of Aerobic Training along with Resveratrol on Mitochondrial Dynamics of Cardiac Myocytes in Animal Model of Non-alcoholic Fatty Liver Disease. Journal of Ardabil University of Medical Sciences. 2019;19(3):272-83.[
doi.org/10.29252/JARUMS.19.3.272]. [In Persian]
38-Hart N, Sarga L, Csende Z, Koltai E, Koch LG, Britton SL, et al. Resveratrol enhances exercise training responses in rats selectively bred for high running performance. Food and chemical toxicology. 2013;61:53-9.[
doi.org/10.1016/j.fct.2013.01.051].
39-Johnson J, Mercado-Ayon E, Mercado-Ayon Y, Dong YN, Halawani S, Ngaba L, et al. Mitochondrial dysfunction in the development and progression of neurodegenerative diseases. Archives of biochemistry and biophysics. 2021;702:108698.[
doi.org/10.1016/j.abb.2020.108698].
40-Wang Y-C, Kong W-Z, Jin Q-M, Chen J, Dong L. Effects of salvianolic acid B on liver mitochondria of rats with nonalcoholic steatohepatitis. World Journal of Gastroenterology: WJG. 2015;21(35):10104.[ doi:
10.3748/wjg.v21.i35.10104].
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