نوع مقاله : مقاله پژوهشی Released under (CC BY-NC) license I Open Access I
نویسندگان
1 استادیار دانشگاه آزاد اسلامی واحد آیت الله آملی
2 کارشناس ارشد فیزیولوژی ورزش
چکیده
هدف: فعالیت ورزشی یک راهبرد موفق و قدرتمند برای پیشگیری از بیماری های قلبی عروقی است. با این حال، مطالعات نشان داده اند که ورزش حاد می تواند غلظت شاخص های قلبی را افزایش دهد. هدف از این مطالعه بررسی اثر یک دوره مسابقه کشتی همراه با مصرف مکمل بتاآلانین بر برخی شاخص های آسیب قلبی در کشتی گیران نخبه بود.
روش پژوهش: تعداد16 کشتیگیر به عنوان آزمودنی (در هر وزن دو نفر) انتخاب و به طور هدفمند به دو گروه کنترل و تجربی تقسیم شدند. گروه مکمل مقدار 1000 میلیگرم مکمل بتالانین را 4ساعت قبل از انجام پروتکل مصرف نمودند. برنامه تمرینی شامل یک دوره مسابقه کشتی شبیه سازی شده بود که در این مسابقه کشتی گیران با فواصل تقریبی نیم ساعته چهار مسابقه کشتی را برگذار کردند. نمونه گیری خونی از ورید بازویی به مقدار 8 سیسی قبل، بلافاصله و یک ساعت بعد از برنامه تمرینی جمعآوری شد. دادهها با استفاده از آزمون t و تحلیل واریانس با اندازهگیری مکرر در سطح 05/0α≤ تجزیه و تحلیل شدند.
یافتهها: نتایج نشان داد یک جلسه مسابقه کشتی همراه با مصرف مکمل بتاآلانین بر تروپونین I و تروپونین T اثر معنی‌داری ندارد (05/0>P). با این وجود، یک جلسه مسابقه کشتی همراه با مصرف مکمل بتاآلانین موجب افزایش معنی‌دار CKmb و LDH شد (05/0>P).
نتیجه‌گیری: بهنظر میرسد میزان شاخص های آسیب قلبی (ترپونین I و T) به دنبال فعالیت شدید و مصرف مکمل بتا الانین در ورزشکاران با آمادگی بالا تغییر نمی کند.
واژگان کلیدی: بتاآلانین، شاخص های آسیب قلبی، کشتی گیران نخبه
کلیدواژه‌ها
عنوان مقاله [English]
The effects of a session wrestling match with beta-alanine supplementation on some indicators of heart damage in elite wrestlers
نویسندگان [English]
- A Abdi 1
- M Nasiri 2
- A Abbasi 1
1 Assistant Professor at University of Islamic Azad University of Ayatollah Amoli
2 MSc in Exercise Physiology
چکیده [English]
Aim: Exercise training represents a successful and powerful strategy to prevent future cardiovascular disease. However, Studies have shown that acute exercise can increase serum concentrations of cardiac biomarkers. The aim of this study was to investigate the effects of a session wrestling match with beta-alanine supplementation on some indicators of heart damage in elite wrestlers.
Methods: 16 wrestlers as subjects (two men in each weight) were selected and purposefully they were divided into control and experimental groups. Supplement group consumption 1000 mg beta-alanine for 4 hours before the protocol. The training program includes a course of the match was simulated, the wrestler held four wrestling match at intervals of half-hour. The amount of 8 ml blood samples from the brachial vein before, immediately after and one hour after the exercise program were collected. Data were analyzed with using of t test and analysis of variance with repeated measures at αResults: The results showed that a session of wrestling match with beta-alanine supplementation had no significant effect on troponin I and troponin T (P=0.05). a session of wrestling match with beta-alanine supplementation were significantly increased CKmb and LDH (P=0.000).
Conclusion: It seems indicators damage the heart (cardiac troponin I and T) to follow the intense activity and beta-alanine supplementation does not change in athletes with high fitness.
کلیدواژه‌ها [English]
- Keywords: Beta-alanine
- Indicators of heart damage
- Elite wrestlers
- Adams J, Abendschein DR, Jaffe AS. Biochemical markers of myocardial injury. Is MB creatine kinase the choice for the 1990s? Circulation.1993; 88(2): 750-763.
- Aonuma S, HAMA T, TAMAKI N, OKUMURA H. Orotate as a β-alanine donor for anserine and carnosine biosynthesis, and effects of actinomycin D and azauracil on their pathway. Journal of biochemistry. 1969; 66(2): 123-132.
- Baty JJ, Hwang H, Ding Z, Bernard JR, Wang B, Kwon B, et al. The effect of a carbohydrate and protein supplement on resistance exercise performance, hormonal response, and muscle damage. Journal of Strength and Conditioning Research. 2007; 21(2): 321.
- Boldyrev AA, Aldini G, Derave W. Physiology and pathophysiology of carnosine. Physiol Rev 2013; 93:1803–45.
- Brancaccio P, Maffulli N, Limongelli FM. Creatine kinase monitoring in sport medicine. British medical bulletin. 2007; 81(1): 209-230.
- Calvani M, Reda E, Arrigoni-Martelli E. Regulation by carnitine of myocardial fatty acid and carbohydrate metabolism under normal and pathological conditions. Basic research in cardiology. 2000; 95(2): 75-83.
- Green MS, Corona, BT, Doyle JA, Ingalls CP. Carbohydrate-protein drinks do not enhance recovery from exercise-induced muscle injury. International journal of sport nutrition and exercise metabolism. 2008; 18(1): 1-18.
- Horswill CA. Physiology and nutrition for wrestling. Physiology and nutrition for competitive sport. 1994; 1004, 131-180.
- Koba T, Hamada K, Sakurai M, Matsumoto K, Hayase H, Imaizumi K, et al. Branched-chain amino acids supplementation attenuates the accumulation of blood lactate dehydrogenase during distance running. The Journal of sports medicine and physical fitness. 2007; 47(3): 316-322.
10. Kong Z, Nie J, Lin H, George K, Zhao G, Zhang H, Tong TK, Shi Q. Sex differences in release of cardiac troponin T after endurance exercise. Biomarkers. 2017; 22(4):345-350.
11. Le Goff C, Jean-François Kaux, Stéphanie D’Otreppe, Sébastien Goffaux, Marianne Fillet, Jean-Paul Chapelle, Etienne Cavalier. Release of Cardiac Biomarkers during a Cycling Race. World Journal of Cardiovascular Diseases, 2016, 6, 285-294
12. Marginson V, Rowlands AV, Gleeson NP, Eston RG. Comparison of the symptoms of exercise-induced muscle damage after an initial and repeated bout of plyometric exercise in men and boys. Journal of applied physiology. 2005; 99(3): 1174-1181.
13. Miura M, Umeda T, Nakaji S, Liu Q, Tanabe M, Kojima A, et al. Effect of 6 months' training on the reactive oxygen species production capacity of neutrophils and serum opsonic activity in judoists. Luminescence. 2005; 20(1): 1-7.
14. O'Dowd A, O'Dowd JJ, MacFarlane N, Abe H, Miller DJ. Analysis of novel imidazoles from isolated perfused rabbit heart by two high-performance liquid chromatographic methods. Journal of Chromatography B: Biomedical Sciences and Applications. 1992; 577(2): 347-353.
15. O'Hanlon R, Wilson M, Wage R, Smith G, Alpendurada FD, Wong J, et al. Research Troponin release following endurance exercise: is inflammation the cause? a cardiovascular magnetic resonance study. (2010; 12(38): 1-7.
16. Rahnama N, Faramarzi M, Gaeini AA. Effects of intermittent exercise on cardiac troponin i and creatine kinase-MB. Int J Prev Med. 2011; 2(1):20-3.
17. Ranjbar R, Ahmadi MA, Zar A, Krustrup P. Acute effect of intermittent and continuous aerobic exercise on release of cardiac troponin T in sedentary men. Int J Cardiol. 2017 1;236:493-497.
18. Romano-Ely BC, Todd MK, Saunders MJ, Laurent TS. Effect of an isocaloric carbohydrate-protein-antioxidant drink on cycling performance. Medicine and science in sports and exercise. 2006; 38(9): 1608-1616.
19. Scharhag J, George K, Shave R, Urhausen A, Kindermann W. Exercise-associated increases in cardiac biomarkers. Medicine+ Science in Sports+ Exercise. 2008; 40(8): 1408
20. Shave R., Ross P, Low D, George K, Gaze D. Cardiac troponin I is released following high-intensity short-duration exercise in healthy humans. International journal of cardiology. 2010; 145(2): 337-339.
21. Shave R., Whyte G, George K, Gaze D, Collinson P. Prolonged exercise should be considered alongside typical symptoms of acute myocardial infarction when evaluating increases in cardiac troponin T. Heart. 2005; 91(9): 1219-1220.
22. Stepura O, Martynow A. Magnesium orotate in severe congestive heart failure (MACH). International journal of cardiology. 2009; 134(1): 145-147.
23. Usui T, Kubo Y, Akanuma, S, Hosoya K. β-Alanine and l-histidine transport across the inner blood-retinal barrier: potential involvement in l-carnosine supply. Experimental eye research. 2013; 113: 135-142.
24. Walsh B, Tonkonogi M, Malm C, Ekblom B, Sahlin K. Effect of eccentric exercise on muscle oxidative metabolism in humans. Medicine and science in sports and exercise, 2001; 33(3): 436-441.
25. Weber KT, Janicki JS. Cardiopulmonary exercise testing: physiologic principles and clinical applications: Saunders. 1987; 42(1): 80-89.
26. Zebblin M, Sullivan S, Baier M, King S. Branched-chain amino acid supplementation maintains muscle power following eccentric exercise. The FASEB Journal. 2007; 5(2): 21-32.
27. Zhao Y, Zhao B. Protective effect of natural antioxidants on heart against ischemia-reperfusion damage. Current pharmaceutical biotechnology. 2010; 11(8): 868-874.
)