اثر شش هفته تمرین تناوبی شدید با مکمل‌یاری زردچوبه بر آیریزین و UCP1 در زنان چاق

نوع مقاله: مقاله پژوهشی

نویسندگان

1 دانشجوی دکتری بیوشیمی و متابولیسم ورزشی

2 دانشیار دانشگاه تبریز

چکیده

هدف:  آیریزین، یکی از عواملی است که آثار مفید فعالیت ورزشی بر تغییر بافت آدیپوز، پروتئین جفت نشده1 (UCP1) و متابولیسم را میانجی­گری می­کند. بنابراین هدف از مطالعه حاضر تعیین تأثیر شش هفته تمرین تناوبی شدید با مکمل­یاری زردچوبه بر مقادیر آیریزین، UCP1 و ترکیب بدن در زنان چاق بود.
روش‌شناسی: سی زن چاق (kg.m2 78/1± 08/33 BMI=) با دامنه سنی 20 الی 25 سال در قالب یک طرح نیمه تجربی با پیش آزمون-پس آزمون، بصورت هدفمند انتخاب شد و بطور تصادفی به دو گروه پانزده نفره تمرین تناوبی شدید (HIIT) - دارونما و گروه تمرین HIIT - مکمل زردچوبه (سه میلی­گرم کورکومین به ازای هر کیلوگرموزن بدن در یک روز) تقسیم ­شد. دوره آماده­سازی به مدت سه هفته و تمرین HIIT به­ مدت شش هفته انجام شد (چهار جلسه در هفته). نمونه­های خونی در دو مرحله قبل و 48 ساعت بعد از آخرین جلسه تمرینی در فاز فولیکولی گرفته شد. آیریزین و UCP1 سرمی به روش الایزا اندازه­گیری شدند.
یافته‌ها: در هر دو گروه بعد از نه هفته مداخله مقادیر آیریزین، چربی زیرپوستی و BMI بطور معنی­داری کاهش یافت، و مقادیر UCP1 و حداکثر اکسیژن مصرفی بطور معنی­داری افزایش یافت (05/0P<). تفاوت بین­گروهی معنی­داری برای مقادیر آیریزین، UCP1، چربی زیرپوستی کل، BMI و VO2max وجود نداشت (05/0P> ).
نتیجه‌گیری: شش هفته تمرین تناوبی شدید با مکمل­یاری زردچوبه احتمالا می­تواند با کاهش مقادیر آیریزین و افزایش مقادیر UCP1، ترکیب بدن را بهبود بخشد.
 

کلیدواژه‌ها


عنوان مقاله [English]

Effect of six weeks high intensity interval training with turmeric supplementation on irisin and UCP1 in obese females

نویسندگان [English]

  • Z Rostami Hashjin 1
  • R Amirsasan 2
  • S Nikoukheslat 2
  • V Sari-Sarraf 2
1 PhD student in exercise biochemistry and metabolism
2 Associated Professor, University of Tabriz
چکیده [English]

Aim: Irisin is one of the factors that mediate beneficial effects of exercise on adipose tissue conversion, uncoupling protein1 (UCP1) and metabolism. Therefore, the aim of this study was to determine the effect of six weeks high intensity interval training (HIIT) with Turmeric supplementation on Irisin, UCP1 and body composition in obese females.
Method: Thirty obese women (BMI=33.08±1.78 kg.m-2) age range of 20-25 years in quasi-experimental study with pre-post testing design, were selected purposefully and were randomly divided into two homogeneous groups of 15 participants: HIIT+placebo, and HIIT+Turmeric supplementation (3 milligram curcumin per kilogram body weight per day). Preparation period performed for 3 weeks and HIIT performed for six weeks (4 sessions per week). Blood samples were taken, before and 24 hours after last exercise session in the follicular phase. Serum irisin and UCP1 were measured by ELISA method.
Results: In both groups, irisin levels, subcutaneous fat and BMI significantly decreased (P<0.05), and UCP1 levels and VO2max significantly increased after nine weeks intervention (P<0.05). There was no significant difference between groups for irisin, UCP1, total subcutaneous fat, BMI and VO2max values.
Conclusion: Six weeks high intensity interval training with turmeric supplementation probably could improve body composition by decreasing Irisin and increasing UCP1 levels.
 

کلیدواژه‌ها [English]

  • Keywords: Thermogenin
  • Irisin
  • High Intensity Interval Training
  • Obesity
  • Turmeric

 

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