نوع مقاله : مقاله پژوهشی Released under (CC BY-NC) license I Open Access I

نویسندگان

1 دانشگاه اردکان

2 هیات علمی دانشگاه آزاد اسلامی واحد کردستان

چکیده

هدف: چاقی به عنوان یک شاخص سیستمیک التهابی زمینه ساز بیماری‌های مختلف شناخته شده است. هدف تحقیق حاضر، تاثیر 12 هفته تمرین مقاومتی فزاینده بر سطوح سرمی آنزیم‌های‌ آسپارتات آمینوترانسفراز، آلکالین فسفاتاز و آلانین آمینوترانسفراز کبدی در مردان چاق کم تحرک بود.
روش شناسی: 40 مرد چاق کم‌تحرک (kg.m2 94/2±07/31 BMI=) با دامنه سنی 30 تا 45 سال به صورت هدفمند انتخاب شدند و به طور تصادفی به دو گروه 20 نفره تمرین مقاومتی فزاینده و کنترل تقسیم شدند. تمرین مقاومتی فزاینده به مدت 12 هفته و هفته‌ای 3 جلسه اجرا شد(هفته اول: 15 تکرار-2 دور- 50%1RM؛ هفته دوازدهم: 12 تکرار-3 دور- 80%1RM). نمونه‌های خونی قبل و 24 ساعت بعد از آخرین جلسه تمرینی در حالت 11 ساعت ناشتایی برای تعیین غلظت سرمی آسپارتات آمینوترانسفراز، آلکالین فسفاتاز و آلانین آمینوترانسفراز گرفته شد. داده‌ها با استفاده از آزمون t مستقل و وابسته در سطح معنی داری 05/0 =α تجزیه و تحلیل شدند.
یافته‌ها: نتایج نشان داد 12 هفته تمرین مقاومتی فزاینده بر تغییرات بین گروهی آسپارتات آمینوترانسفراز (003/0p =)، آلکالین فسفاتاز (014/0p =)، آلانین آمینوترانسفراز (040/0p =) و نسبت آسپارتات آمینوترانسفراز به آلانین آمینوترانسفراز (006/0p =) در مردان چاق کم تحرک تاثیر معنی‌دار دارد. تغییرات بین گروهی معنی‌دار در قدرت عضلانی (001/0p =) و درصد چربی بدن (038/0p =) مشاهده شد.
نتیجه‌گیری: 12 هفته تمرین مقاومتی فزاینده احتمالاً با بهبود ترکیب بدن و قدرت عضلانی می‌تواند غلظت آسپارتات آمینوترانسفراز، آلکالین فسفاتاز و آلانین آمینوترانسفراز را در مردان چاق کم ‌تحرک کاهش دهد.

کلیدواژه‌ها

عنوان مقاله [English]

Effect of 12 weeks of progressive resistance training on the serum levels of liver enzymes Aspartate Aminotransferase, Alanine Aminotransferase, Alkaline Phosphatase in sedentary obese men

نویسندگان [English]

  • Hasan Naghizadeh 1
  • kamal Azizbeigi 2

1 University of ardakan

2 Sanandaj Branch, Islamic Azad University,

چکیده [English]

Aim:Obesity is known as an inflammatory systemic indicator of various diseases. The aim of the present study was to investigate the effect of 12 weeks of progressive resistance exercise on serum levels of enzymes aspartate aminotransferase, alkaline phosphatase and alanine aminotransferase in obese men.
Method:Forty sedentary obese men (BMI=31.07 kg.m2) with age range of 30-45 years were purposefully selected and randomly divided into two groups of 20 participants: progressive resistance exercise and control. The exercise protocol for 12 weeks, was carried out three times a week (First week:15 repetitions -2 rounds -50% 1RM; Twelfth week:12 repetitions -3 rounds -80% 1RM).
Blood samples were taken before and 24 hours after the last training session to determine serum concentrations of aspartate aminotransferase, alkaline phosphatase, and alanine aminotransferase. Data were analyzed using independent and dependent t-test at a significance level of α=0.05.
Results:The results showed that 12 weeks of progressive resistance training has significant effect on between group changes of aspartate aminotransferase(p=0.003), alkaline phosphatase (p=0.014), alanine aminotransferase(p=0.040) and the ratio of aspartate aminotransferase to alanine aminotransferase(p=0.006) in sedentary obese men. Significant between group changes were observed in muscle strength(p=0.001) and body fat percentage(p=0.038). Progressive resistance training is likely to reduce the concentration of aspartate aminotransferase, alkaline phosphatase, and alanine aminotransferase in the blood of obese obese men by improving body composition, muscle strength, and oxygen consumption.
Conclusion:Progressive resistance training, possibly with improved body composition and muscle strength, can decrease the concentration of aspartate aminotransferase, alkaline phosphatase, and alanine aminotransferase in sedentary obese men.

کلیدواژه‌ها [English]

  • Aspartate aminotransferase
  • Alanine aminotransferase
  • Alkaline phosphatase
  • Resistance Training
  • Obese Men
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