نوع مقاله : مقاله پژوهشی Released under (CC BY-NC) license I Open Access I

نویسندگان

1 دانشجوی دکترای فیزیولوژی ورزش, گروه تربیت بدنی. واحد نیشابور. دانشگاه آزاد اسلامی, نیشابور, ایران

2 استادیار گروه تربیت بدنی. واحد نیشابور. دانشگاه آزاد اسلامی, نیشابور, ایران

3 دانشیار گروه فیزیولوژی ورزش.دانشکده علوم ورزشی, دانشگاه فردوسی مشهد,مشهد,ایران

چکیده

افزایش سن و زندگی کم‌تحرک سبب تغییرات فیزیولوژیکی منجر به چاقی می‌شود. انجام تمرینات ورزشی و مصرف برخی مکمل‌ها سبب بهبود این وضعیت می‌شود. هدف از پژوهش حاضر اثر دوازده هفته تمرین هوازی‌-مقاومتی و مصرف مکمل اسیداورسولیک بر سطوح آیریزین و فاکتورهای التهابی در مردان میان‌سال دارای اضافه وزن بود.
مواد وروش‌ها: 34 مرد در طرح نیمه تجربی به صورت تصادفی در سه گروه تمرین‌ترکیبی-مکمل (یک) 12نفر، گروه تمرین-ترکیبی-دارونما (دو) 12 نفر و گروه مکمل (سه) 10 نفر تقسیم شدند. گروه‌های تمرینی 12 هفته، هر هفته سه جلسه، روزهای متوالی- مجزا تمرینات هوازی با شدت 60 تا 75% HRmax و تمرینات مقاومتی با شدت 60 تا 75% 1RM انجام دادند. گروه‌های دو و سه روزانه مقدار 450 میلی‌گرم مکمل اسیداورسولیک در سه وعده دریافت کردند. 24ساعت قبل از اولین و 48 ساعت بعد از آخرین جلسه تمرین، نمونه‌ی خونی گرفته شد.
یافته ها: سطوح آیریزین افزایش داشت که این افزایش بین گروه‌های یک و دو (001/0=P) و یک و سه (001/0=P) معنی‌دار بود اما بین گروه دو با سه تفاوت معنی‌دار نبود (00/1=P). همچنین سطوح IL6 و CRP سه گروه‌ کاهش پیدا کرد، این کاهش در IL6 و CRP به ترتیب بین گروه‌های یک و دو (004/0=P)، (001/0=P) و یک و سه (004/0=P)، (001/0=P) معنی‌دار بود اما بین دو و سه (232/0=P)، (078/0=P) معنی‌دار نبود.
نتیجه گیری: نتایج نشان داد افزایش آیرزین و کاهش فاکتورهای التهابی ناشی از انجام تمرینات هوازی-‌مقاومتی و مصرف مکمل اسیداوروسولیک سبب کاهش سطوح چربی شده و برای افراد غیرفعال دارای اضافه وزن مفید باشد

کلیدواژه‌ها

عنوان مقاله [English]

The effect of a course of aerobic-resistance training and ursolic acid consumption on irisin levels and inflammatory factors in overweight middle-aged men

نویسندگان [English]

  • yaser saberi 1
  • Amene Barjasteh yazdi 2
  • rambod khajeiei 2
  • Amir Rashidlamir 3

1 Ph.D. Student of sport Physiology. Department of Exercise Physiology, Neyshabur Branch, Islamic Azad University, Neyshabur,Iran.

2 Assistant professor, Departmant of Exercise Physiology, Neyshabur Branch, Islamic Azad University, Neyshabur, Iran

3 Associate Professor, Department of Sport Biochemistry and Metabolism, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran

چکیده [English]

Aim: Increasing age and sedentary lifestyle cause physiological obesity. Exercising and using some supplements can improve this condition. The aim of the present study was to evaluate the effect of 12weeks of aerobic-resistance training and complete consumption of ursolic acid on irisin levels and inflammatory factors in overweight middle-aged men.
Materials and Methods:
34 men in the semi-experimental design were randomly divided into three groups of combined exercise-supplement (one)12people, exercise-combination-placebo (two)12people, supplement group (three)10people. The training groups performed 12weeks, three sessions per week, consecutive days-separate aerobic exercises with an intensity of 60 to 75%HRmax and resistance exercises with an intensity of 60 to 75%1RM. Groups two and three received 450 mg of ursolic acid supplement in three meals daily. Blood samples were taken 24hours before the first and 48hours after the last training session.

Results:
Irisin levels increased which was significant between groups one and two (P = 0.001) and one and three (P = 0.001) but there was no significant difference between groups two and three.
(P = 1). Also, IL6 and CRP levels decreased in three groups, this decrease in IL6 and CRP between groups one and two (P = 0.004), (P = 0.001) and one and three (P =0.004), (P = 0.001) respectively.it was significant but between two and three (P = 0.232), (P = 0.078) was not significant
Conclusion:
The results showed that increasing irisin, decreasing inflammatory factors due to aerobic-resistance training and urosolic acid supplementation reduces fat levels and is useful for inactive overweight people.

کلیدواژه‌ها [English]

  • "Aerobic-resistance exercises"
  • " ursolic acid supplement"
  • " Irisin":" Inflammatory factors"
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