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لیست داوران سال 1400

تاثیر هشت هفته تمرین مقاومتی همراه با مصرف ویتامین D بر سطوح کمرین و امنتین-1 در افراد مبتلا به دیابت نوع2

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC) license I Open Access I

نویسندگان

1 کارشناسی ارشد، گروه تربیت بدنی و علوم ورزشی، واحد علوم و تحقیقات، دانشگاه آزاد اسلامی، تهران، ایران.

2 دانشگاه آزاد اسلامی، واحد علوم و تحقیقات ، گروه تربیت بدنی و علوم ورزشی ، دانشکده علوم انسانی و اجتماعی، تهران، ایران

3 دانشیار، گروه فیزیولوژی ورزشی، واحد تهران جنوب، دانشگاه آزاد اسلامی، تهران، ایران.

4 دانشیار، گروه تربیت بدنی و علوم ورزشی، واحد علوم و تحقیقات، دانشگاه آزاد اسلامی، تهران، ایران

چکیده

هدف: تغییرات در سطوح آدیپوکاینها نقش مهمی در بروز بیماریهای مختلف از جمله دیابت نوع2 دارد که در بین آنها کمرین و امنتین-1 توجه زیادی را به خود جلب کرده است. در مقابل، تاثیرات مثبت تمرین ورزشی ومصرف ویتامینD در مقابله با اثرات پاتولوژیک دیابت نوع2 گزارش شده است. هدف از اجرای پژوهش حاضر، بررسی تاثیر هشت هفته تمرین مقاومتی همراه با مصرف ویتامین D بر سطوح کمرین و امنتین-1 در افراد مبتلا به دیابت نوع2 بود.
روش‌شناسی: 40 مرد دیابتی نوع2 با میانگین سنی 83/3±19/47 سال ودرصد چربی بدن 49/2±96/30 در چهار گروه دارونما، ویتامینD، تمرینو تمرین+ویتامینD قرار گرفتند. برنامه تمرین مقاومتی به مدت هشت هفته وسه جلسه در هفته با 60 تا 70 درصد 1RM اجرا شد. مصرف ویتامین D نیز روزانه 2000 واحد در نظر گرفته شد و مصرف دارونما (پارافین خوراکی) نیز به همان اندازه در نظر گرفته شد. در ابتدا و انتهای پژوهش، نمونه‌های خونی جمع‌آوری و سطوح کمرین وامنتین-1 اندازه‌گیری و مقاومت به انسولین محاسبه شد. آنالیز یافته‌ها با آزمون آنالیز کوواریانس و آزمون تعقیبی بونفرونی انجام گرفت.
یافتهها: یافته‌های پژوهش حاضر نشان داد که در گروه تمرین و تمرین+ویتامین D، سطوح کمرین با کاهش معنادار و سطوح امنتین-1 با افزایش معناداری همراه بوده است (05/0>p). همچنین، کاهش معنادار مقاومت به انسولین در گروه تمرین و تمرین+ویتامینD مشاهده شد (05/0>p).
نتیجه‌گیری: مصرف ویتامینD می‌تواند تاحدودی تاثیرات هیپوگلیسمیک تمرین مقاومتی را افزایش دهد که این تاثیرات مثبت تمرین مقاومتی و مصرف ویتامین D تاحدودی از طریق افزایش سطوح امنتین1 و کاهش سطوح کمرین اعمال می‌شود.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The effect of eight weeks resistance training along with vitamin D consumption on levels of chemerin and omentin-1 in type 2 diabetic patients.

نویسندگان [English]

  • maryam Molaei Jeghanab 1
  • mandana gholami 2
  • Abdolali Banaeifar 3
  • Farshad Ghazalian 4

1 M.A , department of physical education and sport sciences, science and research branch, Islamic azad university, Tehran, Iran

2 Department of physical education and sport sciences, science and research Branch, Islamic Azad University, Tehran, Iran

3 Associate Professor, Department of Exercise Physiology, Faculty of Physical Education, Islamic Azad University, South Branch, Tehran, Iran.

4 Associate professor, department of physical education and sport sciences, science and research branch, Islamic azad university, Tehran, Iran

چکیده [English]

Aim: Changes in adipokines levels play an important role in the development of different disorders including the type 2 diabetes, which among them, chemerin and omentin-1 attracted a lotof attention. In contrast, positive effect of exercise training and vitaminD consumption have been reported in combating with pathologic effects of type 2 diabetes. The aim of present study is to determine the effect of eight weeks resistance training along withvitaminD consumption on levels of chemerin and omentin-1 in type 2 diabetic patients
Method: 40 diabetics men with average age of 47.19±3.83 years old and body fat percentage 30.96±2.49 assigned in four groups including the placebo, vitaminD, training and training+ vitaminD groups. The resistance training program conducted for eight weeks and three session per week with 60 to 70 percent of 1RM intensity. VitaminD consumption considered daily 2000 iu and placebo (oral paraffin) ingestion considered in the same amount. At the baseline and ending intervention, blood samples collected and the levels of chemerin and omentin-1 were measured and insulin resistance calculated. Data were analyzed by analysis of covariance test and Bonferroni post-hoc test.
Results: The present study findings indicated that in training and training+vitaminD groups the chemerin levels significantly decreased and omentin-1 significantly increased (p<0.05). Moreover, significant decrease of insulin resistance was observed in training and training+vitaminD groups (p<0.05).
Conclusion: VitaminD ingestion can increase the hypoglycemic effects of resistance training partly, which these positive effects of resistance training and vitaminD consumption exerted by increase in omentin1 levels and decrease of chemerin levels.

کلیدواژه‌ها [English]

  • Type 2 Diabetes
  • Adipokine
  • Chemerin
  • Omentin-1

Publisher: University oF Guilan          Copyright © The Authors

   

 

This is an open access article distributed under the following Creative Commons license: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

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سوخت و ساز و فعالیت ورزشی
دوره 11، شماره 2 - شماره پیاپی 2
مهر 1400
صفحه 129-149
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  • تاریخ دریافت: 13 مهر 1401
  • تاریخ بازنگری: 11 آبان 1401
  • تاریخ پذیرش: 16 آبان 1401
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