نوع مقاله : مقاله پژوهشی Released under (CC BY-NC) license I Open Access I

نویسندگان

1 گروه علوم ورزشی، دانشگاه کردستان، کردستان، ایران

2 گروه علوم ورزشی، دانشگاه کردستان، سنندج، ایران

3 گروه فیزیولوژی ورزشی، دانشگاه آزاد اسلامی واحد مرودشت، مرودشت، ایران

چکیده

مقدمه: سالمندی با بروز اختلات شناختی و جسمی همراه است. با توجه به ابهام در اثر تعاملی تمرین و مکمل‌های آنتی‌اکسیدانی، هدف مطالعه حاضر بررسی اثرات فیزیولوژی-روانشناختی تمرینات تناوبی شدید (HIIT) و مصرف ویتامین E (VE) در موش-های صحرایی آلزایمری شده با تری‌متیل‌تین (TMT) بود.
روش‌ها: در این مطالعه تجربی 50 سر موش صحرایی (سن 18-22 ماه؛ وزن 280-320 گرم) آلزایمری شده با تزریق صفاقی mg/kg 10 TMT به گروه‌های (1) TMT، (2) شم/حلال ویتامین E (Sham)، (3) VE، (4) HIIT (90-95 درصد حداکثر سرعت بیشینه) و (5) HIIT+VE تقسیم شدند. تعداد 10 سر موش صحرایی سالم برای بررسی اثر TMT بر متغیر‌های تحقیق در گروه HC قرار گرفتند. تمرینات HIIT به مدت هشت هفته، سه جلسه در هفته انجام شد. ویتامین E برای این مدت با دوز mg/kg 30 به صورت خوراکی به موش‌های صحرایی خورانده شد.
نتایج: در گروه‌های HIIT و HIIT+VE شاخص‌های تن سنجی، وزن غذای دریافتی، اضطراب و افسردگی به طور معنی‌داری کمتر و توان هوازی، تعادل حرکتی، آستانه تحمل درد بیشتر از گروه TMT بود (05/0≥P). در گروه VE وزن چربی احشایی، وزن غذای دریافتی، اضطراب و افسردگی به‌طور معنی‌داری کمتر از گروه TMT بود (05/0≥P). توان هوازی در گروه‌های HIIT و HIIT+VE به‌طور معنی‌داری بیشتر و اضطراب و افسردگی به‌طور معنی‌داری کمتر از گروه VE بود (05/0≥P).
نتیجه‌گیری: به نظر می‌رسد تمرین HIIT، VE و تمرین HIIT+VE دارای اثرات بهبود دهنده شاخص‌های آنتروپومتریکی، عملکرد جسمانی و روانشناختی است؛ اما اثرات عملکرد جسمانی و روانشناختی تمرین HIIT به مراتب قوی‌تر از اثر ویتامین E بود.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Psycho-physiological effects of high intensity interval training and vitamin E consumption in elderly trimethyltin-treated Alzheimer's rats

نویسندگان [English]

  • Omid Reza Salehi 1
  • Dariush Sheikholeslami-Vatani 2
  • Sayed Ali Hosseini 3

1 Department of Sport Sciences, University of Kurdistan, Sanandaj, Iran

2 Department of Sport Sciences, University of Kurdistan, Sanandaj, Iran

3 Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran

چکیده [English]

Introduction: Aging is associated with neurodegenerative and psychological disorders. Considering the ambiguity in the interactive effect of exercise and antioxidants, the aim of this study was to investigate the psycho-physiological effects of high intensity interval training (HIIT) and vitamin E (VE) in elderly trimethyltin (TMT)-treated Alzheimer's rats.
Methods: In this experimental study, 50 Alzheimer's rats (age 18-22 months; weight 280-320 grams) induced by 10 mg/kg TMT were divided into five groups, including: (1) TMT, (2) sham/ vitamin E solvent, (3) VE, (4) HIIT (90-95% of the maximum speed) and (5) HIIT+VE. Ten healthy rats were included in the healthy control (HC) group to investigate the effect of TMT on research variables. HIIT was performed for eight weeks, three sessions per week, and VE was given orally to the rats at a dose of 30 mg/kg.
Results: In the HIIT and HIIT+VE groups, anthropometric indicators, food intake, anxiety and depression were significantly lower, and aerobic capacity, movement balance, and pain tolerance threshold were higher than the TMT group (P≥0.05). In the VE group, visceral fat weight, food intake, anxiety and depression were significantly lower than the TMT group (P≥0.05). Aerobic capacity was significantly higher in HIIT and HIIT+VE groups, and anxiety and depression were significantly lower than in the VE group (P≥0.05).
Conclusion: It seems that HIIT, VE and HIIT + VE improve the weight, BMI and FW and physical and psychological performance, but the effects of HIIT on physical and psychological performance are much stronger than the effect of VE.

کلیدواژه‌ها [English]

  • Training
  • Vitamin E
  • Physical performance
  • Psychological performance
  • Alzheimer's Disease
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