نوع مقاله : مقاله پژوهشی Released under (CC BY-NC) license I Open Access I
نویسندگان
1 گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه شهید چمران اهواز، اهواز، ایران
2 گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی دانشگاه شهید چمران اهواز ، اهواز، ایران
3 گروه فیزیولوژی ورزشی، دانشگاه شهید چمران اهواز
چکیده
مقدمه و هدف: هدف از این پژوهش، بررسی اثر تمرین (مقاومتی-هوازی) بر سطوح IGFBP3, IGF1, BMI زنان چاق می‌باشد. مواد و روش‌ها: به این منظور 24 زن غیرفعال چاق 25 تا 37 ساله با BMI 30 تا 35 کیلوگرم بر مترمربع به‌طور تصادفی به دو گروه 12 نفره تمرین و کنترل تقسیم شدند. تمرین منتخب شامل تمرین مقاومتی با وزنه و دستگاه مخصوص بدنسازی با شدت 67 تا 80 درصد قدرت بیشینه و هوازی با دوچرخه ثابت و شدت 60 تا 85 درصد ضربان قلب بیشینه، به مدت 8 هفته و3 روز در هفته انجام گرفت. اندازه‌گیری‌های ترکیب بدن 24 ساعت قبل 24ساعت بعد از تمرین انجام شد. نمونه‌گیری خونی هم 24 ساعت قبل و48 ساعت بعد از آخرین جلسه تمرین بعد از 12 ساعت ناشتایی انجام شد. برای آنالیز آماری در بخش یافته‌های از آزمون تحلیل کواریانس یک راهه برای بررسی تغییرات بین گروهی استفاده گردید. یافته‌ها: نتایج این پژوهش نشان داد پس از هشت هفته تمرین مقاومتی و هوازی کاهش معنادری در BMI آزمودنی‌های گروه تمرین نسبت به گروه کنترل مشاهد شد(001/0>P). همچنین نتایج آزمون تحلیل کواریانس نشان داد بعد از هشت هفته تمرین منتخب( مقاومتی–هوازی) دو شاخصIGFBP3 IGF1, در گروه تمرین نسبت به گروه کنترل کاهش معناداری پیدا کردند( به ترتیب001/0>P و 006/0>P). نتیجه‌گیری: با توجه به نتایج این تحقیق، هر دو روش تمرینی مقاومتی و هوازی می‌تواند جهت کاهش وزن، BMI IGFBP3 وIGF1 مورد استفاده قرار گیرند.
کلیدواژه‌ها
موضوعات
عنوان مقاله [English]
The effect of eight weeks of resistance and aerobic training on the levels of IGFBP 3, IGF1, and BMI in obese women of Ahvaz city
نویسندگان [English]
- mina shakhi 1
- Aboalhamid habibi 2
- aliakbar alizadeh 3
1 Department of Sports Physiology, Faculty of Sports Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran
2 Departmant sport physiology، Shahid Chamran University، Ahvaz، Ahvaz،Iran
3 Department of Sports Physiology, Faculty of Sports Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran
چکیده [English]
Introduction and purpose: The purpose of this research is to investigate the effect of exercise (resistance-aerobic) on the levels of IGFBP3, IGF1, and BMI in obese wome .Materials and methods: For this purpose, 24 inactive obese women aged 25 to 37 years with a BMI of 30 to 35 kg/m2 were randomly divided into two groups of 12 people, training and control. The selected exercise included resistance training with weights and a special bodybuilding machine with an intensity of 67 to 80% of the maximum strength and aerobic exercise with a stationary bike and an intensity of 60 to 85% of the maximum heart rate, for 8 weeks and 3 days a week. Body composition measurements were taken 24 hours before and 24 hours after exercise. For statistical analysis in the findings section, one-way analysis of covariance test was used to examine inter-group changes. Findings: The results of this study showed that after eight weeks of resistance and aerobic training, a significant decrease in the BMI of subjects in the training group was observed compared to the control group (P<0.001). Also, the results of analysis of covariance showed that after eight weeks of selected training (resistance-aerobic) the two indexes of IGFBP3 and IGF1 in the training group decreased significantly compared to the control group (P<0.001 and P<0.006, respectively). Conclusion: According to the results of this research, both resistance and aerobic training methods can be used to reduce weight, BMI, IGFBP3 and IGF1.
کلیدواژه‌ها [English]
- Resistance and aerobic training
- obese women
- IGFBP3
- IGF1
- BMI
- Calcaterra, V., Vandoni, M., Rossi, V., Berardo, C., Grazi, R., Cordaro, E., Zuccotti, G. (2022). Use of physical activity and exercise to reduce inflammation in children and adolescents with obesity. International Journal of Environmental Research and Public Health, 19(11), 6908.
- Waters, D. L., Aguirre, L., Gurney, B., Sinacore, D. R., Fowler, K., Gregori, G., ... & Villareal, D. T. (2022). Effect of aerobic or resistance exercise, or both, on intermuscular and visceral fat and physical and metabolic function in older adults with obesity while dieting. The Journals of Gerontology: Series A, 77(1), 131-139.
- Armstrong, A., Jungbluth Rodriguez, K., Sabag, A., Mavros, Y., Parker, H. M., Keating, S. E., & Johnson, N. A. (2022). Effect of aerobic exercise on waist circumference in adults with overweight or obesity: A systematic review and meta‐analysis. Obesity Reviews, 23(8), e13446.
- van Baak, M. A., Pramono, A., Battista, F., Beaulieu, K., Blundell, J. E., Busetto, L., ... Oppert, J. M. (2021). Effect of different types of regular exercise on physical fitness in adults with overweight or obesity: Systematic review and meta‐analyses. Obesity Reviews, 22, e13239.
- Silva-Reis, A., Brandao-Rangel, M. A. R., Moraes-Ferreira, R., Gonçalves-Alves, T. G., Souza-Palmeira, V. H., Aquino-Santos, H. C., ... & Vieira, R. P. (2022). Combined resistance and aerobic training improves lung function and mechanics and fibrotic biomarkers in overweight and obese women. Frontiers in Physiology, 13.
- Pazoki, A. R., & Arshadi, S. (2019). Effect of 8 week consumption flax seed supplementation with endurance training on BDNF and IGF-1 in obese women. Journal of Medicinal Plants, 18(70), 188-196.
- Mohammadyari, S., Hadi, H., & Zohrabi, A. R. (2021). The effect of intense intermittent exercise on plasma levels of myostatin and IGF-1 in obese adolescents. Journal of Applied Health Studies in Sport Physiology, 8(2), 18-24.
- Zarghami N.Bahrami A.Mobasseri M.Larijani B.Karimi P.Alanii B. Evaluation of correlation and healthy controls.Iran J Diabetes Lipid Disord 2006;5:187-196.(Persian).
- Boughanem, H., Yubero-Serrano, E. M., López-Miranda, J., Tinahones, F. J., & Macias-Gonzalez, M. (2021). Potential role of insulin growth-factor-binding protein 2 as therapeutic target for obesity-related insulin resistance. International Journal of Molecular Sciences, 22(3), 1133.
- Rashidi E,Hosseini kakhak , SAS, Askari R . The effect of 8 weeks resistance training with low load and high load on testosterone,insulin –like growth factor -1, insulin –like growth.
- Sood, S. (2010). Insulin-like growth factor 1 genotype and muscle power response to strength training in older men and women (Doctoral dissertation(.
- Rashidi E, Hosseini Kakhak SAR,Askari R,The effect of 8 weeks resistance training with low load and high load on testosterone,insulin-like growth factor binding protein-3 levels,and functional adaptations in older women.Iranian Journal of Ageing . 2019;14(3):356-67.(in Persian)
- BermonS,Ferrari P,Bernard P,Altre S,Dolisi C,Responses of total and insulin –like growth factor -1 and insulin-like growth factor binding protein -3 after resistance exercise and training in elderi subjects.Acta physiol Scand 1999;165:51-56
- Kraemer WJ,Gordon SE,Fleck SJ, Marchitlli LJ,Mello R, Dziadose JE, et al. Endogenous anabolic hormonal and growth factor responses to heavy resistance exercise in males and females .Int J Sports med 1991;12:228-235
15.Lavoie JM,Fillion Y, Couturier K,Corriveau P. Selected Contribation :evidence that the decrease in liver glycogen is associated with the exercise-induced increase in IGFBP-1.J Appl Physiol 2002; 93:798=804.
- Whal P,Zinner C,Achtzehn S,BlochW,Mester J.Effect of high and low –intensity exercise and metabolic and acidosis on levels of GH,IGF-1,IGFBP-3 and cortisol.Growth Horm IGF Res 2010;20:380-385.
- West DW,Burd NA,Staples AW,Phillips SM.Human exercise-mediated skeletal muscle hypertrophy is an intrinsic process.The International journal of Biochemistry and cell Biology.2010;42(9):1371-5.
- Nowruzpur; M, Marandi; M. Qanbarzadeh; farms; A. Combined exercise on serum concentration of inflammatory cytokines and factors related to metabolic disorder in elderly women with fatty liver. Journal of Exercise Physiology and Physical Activity. 2022, 15, 2, 75-67.
- Cassilhas RS,Vinna VA,Grassmann V,Santos RT,Santos RF,Tufik S,et al,The impact of resistance exercise on the cognitivw function of eldery .Medicine and Science in Sports and Exercise.2007;39(8):1401-7.
- Saranavard;A. Ghofrani;M, Amiri;s.The effect of eight weeks of combined aerobic training on visfatin serum levels and anthropometric indices of obese young girls.(2013), biquarterly journal of applied health studies in exercise physiology, 6(2), 65-72.
- Mardanpour-Shahrekordi, Z., Banitalebi, E., Faramarzi, M., Bagheri, L., & Mardanpour-Shahrekordi, E. The effect of sequence order of combined training (resistance and endurance) on strength, aerobic capacity and body composition in older women: a randomized clinical trial. Journal of Shahrekord University of Medical Sciences, 2015, 17(3).
- Green JS,Stanforth PR , Rankinen T ,Leon AS,Rao Dc Dc,Skinner JS,et al.The effects of exercise training on abdominal visceral fat ,body composition ,and indicators of the metabolic syndrome in postmenopausal women with and without estrogen replacement therapy :the HERITAGE family study.Metabolism 2004;53:1192-1196.
- Jafari, A., Arazi, H., Ghadian, A., & Hesrak, K. (2019). The Impact of Combined (Aerobic-resistance) Training on Serum Levels of IGF-I and IGFBP-3 in Men with Prostate Cancer. Journal of Advances in Medical and Biomedical Research, 27(122), 35-41.
- Santa Mina D, Connor KM, Alibhai Sh, et al. Exerciseeffects on adipokines and the IGF axis in men with prostatecancer treated with androgen deprivation: A randomizedstudy. Can Urol Assoc J. 2013; 7(11-12): E692-E698.
- David A, Hwa V, Metherell LA, Netchine I, Camacho-Hübner C, Clark AJ, et al. Evidence for a continuum of genetic, phenotypic, and biochemical abnormalities in children with growth hormone insensitivity. Endocr rev. 2011 Aug; 32(4):472-497..
- Azadi, B., Boboli, L., Khani, M., Siahkohian, M., & Pourrahim, A. (2021). The Effect of Eight Weeks of Polarized Training on GH/IGF-1 Axis Hormones Response in Active Young Male. Journal of Ardabil University of Medical Sciences, 21(1), 113-122.
- Zinner C, Wahl P, Achtzehn S, Reed J, Mester J. Acute hormonal responses before and after 2 weeks of HIT in well trained junior triathletes. Int J Sports Med. 2014 Sep; 35(4):316-22.
- Rosenblat MA, Perrotta AS, Vicenzino B. Polarized vs. threshold training intensity distribution on endurance sport performance: a systematic review and meta-analysis of randomized controlled trials. J Strength Cond Res. 2019 Dec; 33(12):3491-3500.
- Schmitz KH, Ahmed RL, Hannan PJ, Yee D. Safety and efficacy of weight training in recent breast cancer survivors to alter body composition, insulin, and insulin-like growth factor axis proteins. Cancer Epid Prev Biom. 2005; 14(7): 1672-80.
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