عنوان مقاله [English]
نویسندگان [English]چکیده [English]
Aim: The purpose of this study was to examine the effect of short term Beta-hydroxyl beta-methylbutyrate (HMB ) supplementation on plasma creatine phosphokinase (CPK) level after resistance training program, in untrained women.
Method: Sixteen untrained women, aged 24.3±1 years, height 163±2.35 cm and weight 61.5±2.25 kg were selected and randomly divided into two HMB supplementation (n=8) and placebo (n=8) groups. All subjects trained 3 times per week for 2 weeks. HMB group and placebo group received 3 gr/day of HMB and placebo, respectively.The muscle injury marker (CPK) and upper and lower body 1-RM were measured in pre and three post tests. To investigate the differences between pre and post-test results in each group Bonferroni test was used and the difference between two groups was determined by independent student t-test.
Results: The result showed that the mean of plasma CPK level was significantly (P<0.05) decreased in HMB supplementation group. This decrease, however, was not found in placebo group. Also upper and lower body 1-RM in HMB and placebo groups were increased, but these increases were not statistically significant.
Conclusion: Supplementation of 3 gr HMB result in a decrease creatine phosphokinase response after resistance training. This finding support the hypothesis that HMB supplementation prevents exercise induced muscle damage, specially in beginner female following resistance training.
Key words: HMB supplementation, Muscle injury, Creatine phosphokinase,